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Patent Agency Ranking
公开(公告)号：WO2014012107A2
公开(公告)日：2014-01-16
申请号：PCT/US2013050531
申请日：2013-07-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： LAGACE ROBERT
IPC: C12Q1/68
CPC classification number: C12Q1/6853 , C12Q1/6855 , C12Q2525/131
Abstract: The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids which belong to a panel of single nucleotide polymorphisms (SNPs) useful to identify a human. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences in the panel. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to identify a human.
Abstract translation: 本发明提供了可用于多属性PCR的多属性的方法，组合物，试剂盒，系统和装置，所述核酸属于用于鉴定人的单核苷酸多态性（SNP）的一组。 特别地，提供允许在面板中选择性扩增一个或多个靶序列的各种靶特异性引物。 在一些方面，使用所公开的方法，试剂盒，系统和装置获得的扩增靶序列可用于包括核酸测序在内的各种下游过程并用于鉴定人。
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公开(公告)号：WO2011066467A3
公开(公告)日：2011-10-27
申请号：PCT/US2010058111
申请日：2010-11-24
Applicant: LIFE TECHNOLOGIES CORP , GREEN ROBERT , MULERO JULIO , HENNESSY LORI , LAGACE ROBERT , CHANG CHIEN-WEI
Inventor： GREEN ROBERT , MULERO JULIO , HENNESSY LORI , LAGACE ROBERT , CHANG CHIEN-WEI
CPC classification number: C12Q1/6876 , C12Q2600/156 , C12Q2600/166
Abstract: Disclosed are rare short tandem repeat (STR) alleles within the D10S1248 and D12S391 loci in humans. Provided are representative allelic ladders for each locus, methods and assays using these alleles and kits containing allelic ladders comprising these alleles for accurate genotyping and identification of a wide range of individuals.
Abstract translation: 在人类D10S1248和D12S391位点内公开了罕见的短串联重复（STR）等位基因。 提供了每个基因座的代表性等位基因梯，使用这些等位基因的试剂盒和方法以及含有包含这些等位基因的等位基因梯的试剂盒，用于精确基因分型和鉴定各种个体。
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公开(公告)号：WO2011020075A3
公开(公告)日：2011-04-14
申请号：PCT/US2010045544
申请日：2010-08-13
Applicant: LIFE TECHNOLOGIES CORP
Inventor： MULERO JULIO , GREEN ROBERT , LAGACE ROBERT , HENNESSY LORI
CPC classification number: C07H21/04 , C12Q1/6879 , C12Q2600/156
Abstract: Disclosed are methods for gender determination in the intron 1 region of the amelogenin locus and a newly discovered single nucleotide polymorphism (SNP) within the X chromosome of the amelogenin locus which can cause allelic dropout. Also disclosed are kits useful in gender determination.
Abstract translation: 公开了用于在釉原蛋白基因座的内含子1区域中确定性别的方法以及可能导致等位基因辍学的釉原蛋白基因座的X染色体内新发现的单核苷酸多态性（SNP）的方法。 还公开了用于性别决定的试剂盒。
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公开(公告)号：EP2464754A4
公开(公告)日：2012-11-14
申请号：EP10808855
申请日：2010-08-13
Applicant: LIFE TECHNOLOGIES CORP
Inventor： MULERO JULIO , GREEN ROBERT , LAGACE ROBERT , HENNESSY LORI
CPC classification number: C07H21/04 , C12Q1/6879 , C12Q2600/156
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公开(公告)号：EP2504433A4
公开(公告)日：2013-06-19
申请号：EP10833985
申请日：2010-11-24
Applicant: LIFE TECHNOLOGIES CORP
Inventor： GREEN ROBERT , MULERO JULIO , HENNESSY LORI , LAGACE ROBERT , CHANG CHIEN-WEI
CPC classification number: C12Q1/6876 , C12Q2600/156 , C12Q2600/166
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