公开(公告)号：WO2022006368A2

公开(公告)日：2022-01-06

申请号：PCT/US2021/040037

申请日：2021-07-01

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： KORE, Anilkumar ,  ANNAMALAI, Senthilvelan ,  MUTHIAN, Shanmugasundaram ,  POTTER, Robert ,  VONDERFECHT, Tyson

IPC: C07H21/00 ,  C07H1/00 ,  C12N15/00 ,  A61K31/7088 ,  A61K38/45 ,  A61K47/549 ,  C12N15/11 ,  C12N2310/3231 ,  C12N2310/3519 ,  C12N2320/32 ,  C12N9/1247 ,  C12Y207/07006

Abstract: This specification generally relates to trinucleotide RNA cap analogs, methods of use thereof, and kits comprising same. In particular, the trinucleotide cap analogs provided herein permit ready detection and/or isolation of capped RNA transcripts in vitro and translation of capped mRNAs in vivo.

公开(公告)号：EP4175967A2

公开(公告)日：2023-05-10

申请号：EP21746278.7

申请日：2021-07-01

Applicant: Life Technologies Corporation

Inventor： KORE, Anilkumar ,  ANNAMALAI, Senthilvelan ,  MUTHIAN, Shanmugasundaram ,  POTTER, Robert ,  VONDERFECHT, Tyson

IPC: C07H21/00 ,  C07H1/00 ,  C12N15/00