公开(公告)号：WO2013134431A1

公开(公告)日：2013-09-12

申请号：PCT/US2013/029452

申请日：2013-03-06

Applicant: LIFE TECHNOLOGIES CORPORATION ,  RAMACHANDRAN, Niroshan ,  MENG, Lihao ,  CHEN, Gengxin ,  BOURDON, David ,  VAN LE, Suzy

Inventor： RAMACHANDRAN, Niroshan ,  MENG, Lihao ,  CHEN, Gengxin ,  BOURDON, David ,  VAN LE, Suzy

IPC: G01N33/564 ,  G01N33/68

CPC classification number: G01N33/564 ,  G01N33/6893 ,  G01N2333/52 ,  G01N2333/523 ,  G01N2800/104 ,  G01N2800/52

Abstract: The disclosure provides novel SLE biomarkers. The disclosure further provides kits and methods of diagnosing, prognosing, and stratifying subjects with the disease by utilizing the novel SLE biomarkers.

Abstract translation: 本公开提供了新型SLE生物标志物。 本公开进一步提供了通过利用新型SLE生物标志物诊断，预测和分层患有疾病的受试者的试剂盒和方法。

公开(公告)号：WO2015039014A1

公开(公告)日：2015-03-19

申请号：PCT/US2014/055615

申请日：2014-09-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： SHIN, Hon Siu ,  KOO, Chin Yong ,  LEE, Way Xuang ,  LIM, Chee Kiong ,  CHING, Chee Wee ,  RAMACHANDRAN, Niroshan

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1822

Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.

Abstract translation: 公开了一种包括样品块和两个或更多个热电装置的热块组件。 样品块具有构造成容纳多个反应容器和相对的底表面的顶表面。 热电装置可操作地耦合到样品块，其中每个热电装置包括用于热传感器的壳体和具有控制器的热控制界面。 每个热电装置进一步构造成彼此独立地操作以在整个样品块中提供基本均匀的温度分布。

公开(公告)号：EP3046671A1

公开(公告)日：2016-07-27

申请号：EP14777985.4

申请日：2014-09-15

Applicant: Life Technologies Corporation

Inventor： SHIN, Hon Siu ,  KOO, Chin Yong ,  LEE, Way Xuang ,  LIM, Chee Kiong ,  CHING, Chee Wee ,  RAMACHANDRAN, Niroshan

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1822

Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.