公开(公告)号：WO2017066358A1

公开(公告)日：2017-04-20

申请号：PCT/US2016/056693

申请日：2016-10-12

Applicant: LOMA LINDA UNIVERSITY

Inventor： PAI, Ramdas, G. ,  SLATER, Jerry, D. ,  SCHULTE, Reinhard, W. ,  NIE, Ying ,  PAI, Sudha

IPC: A61B5/113 ,  A61B6/03 ,  A61B5/08 ,  A61B5/055 ,  A61N5/10 ,  H01J3/08 ,  H01J3/14

CPC classification number: A61B5/055 ,  A61B5/0044 ,  A61B5/0073 ,  A61B5/113 ,  A61B5/7207 ,  A61B6/032 ,  A61B6/4258 ,  A61B6/503 ,  A61B18/18 ,  H01J3/08 ,  H01J3/14

Abstract: Embodiments include methods and systems to perform computed tomography. Respiratory signal data and imaging data associated with a heart can be received, and a target area of the heart can be determined responsive to the imaging data. An initial energy and a direction of a proton beam to deliver a Bragg peak of the proton beam to the target area can be determined. The initial energy and the direction of the proton beam then can be modified responsive to the respiratory signal data to generate a modified initial energy and a modified direction. A proton computed tomography controller can be instructed to deliver the proton beam to the heart at the modified initial energy and the modified direction.

Abstract translation: 实施例包括执行计算机断层摄影的方法和系统。 可以接收与心脏相关联的呼吸信号数据和成像数据，并且可以响应于成像数据来确定心脏的目标区域。 可以确定质子束的初始能量和方向以将质子束的布拉格峰传送至目标区域。 然后可以响应于呼吸信号数据修改质子束的初始能量和方向，以生成修改的初始能量和修改的方向。 质子计算机断层扫描控制器可以被指示将质子束以改变的初始能量和修改的方向递送到心脏。