Abstract:
A method of treating a first chemical species in a gas using a plasma, the method including the steps of providing an array of micro-scale cavity discharge devices capable of sustaining the plasma where the first chemical species is capable of flowing proximate to the array of micro-scale cavity discharge devices, wherein the first chemical species is converted to a second chemical species within the plasma.
Abstract:
The present invention is directed to devices and methods for manipulating polarizable analytes via dielectrophoresis to allow for improved detection of target analytes. Microfluidic devices are configured such that the application of a voltage between field-generating electrodes results in the generation of an asymmetric electric field within the device. Some embodiments of the invention provide a physical constriction, and electrically floating conductive material or a combination of the two techniques to generating an asymmetrical field. Using dielectrophoresis, target analytes are concentrated or separated from contaminant analytes and transported to a detection module.
Abstract:
The present invention is directed to devices and methods for manipulating polarizable analytes via dielectrophoresis to allow for improved detection of target analytes. Microfluidic devices are configured such that the application of a voltage between field-generating electrodes results in the generation of an asymmetric electric field within the device. Some embodiments of the invention provide a physical constriction, and electrically floating conductive material or a combination of the two techniques to generating an asymmetrical field. Using dielectrophoresis, target analytes are concentrated or separated from contaminant analytes and transported to a detection module.
Abstract:
The present invention is directed to devices and methods for manipulating polarizable analytes via dielectrophoresis to allow for improved detection o f target analytes. Microfluidic devices (405) are configured such that the application of a voltage between field-generating electrodes (420, 421) results in the generation of an asymmetric electric field within the device (405). Some embodiments of the invention provide a physical constriction (410), and electrically floating conductive material (430) or a combination of the two techniques to generate an asymmetrical field. Using dielectrophoresi s, target analytes are concentrated or separated from contaminant analytes and transported to a detection module (440).
Abstract:
An exemplary system and method for detecting at least one analyte in a sample comprises inter alia a source of radiation (300), a near-field aperture array (315), a chromatographic field (330), a detector (350), and a data processor (370). Disclosed features and specifications may be variously controlled, adapted or otherwise optionally modified to improve detection of any sub-diffraction-limited scale phenomena. Exemplary embodiments of the present invention representatively provide for improved S/N, increased sample throughput, refined spectral resolution and enhanced detection sensitivity.
Abstract:
The present invention is directed to devices and methods for manipulating polarizable analytes via dielectrophoresis to allow for improved detection of target analytes. Microfluidic devices (405) are configured such that the application of a voltage between field-generating electrodes (420, 421) results in the generation of an asymmetric electric field within the device (405). Some embodiments of the invention provide a physical constriction (410), and electrically floating conductive material (430) or a combination of the two techniques to generate an asymmetrical field. Using dielectrophoresis, target analytes are concentrated or separated from contaminant analytes and transported to a detection module (440).
Abstract:
An electrochemical analysis device and method for analyzing biomolecular samples, including a means for holding a sample on a substrate platform, a thermal sensor, a biosensor formed having a specific spatial resolution as related to the thermal sensor, and a means for providing radiation to the biomolecular sample. The means for holding the sample, the thermal sensor, the biosensor, and the means for providing radiation all three-dimensionally integrated with the substrate platform, thereby defining a compact biomolecular analysis device having a volume resolution of less than 50 micro liters. During operation, radiation is provided to the biomolecular sample to provide for a constant temperature at which hybridization of the biomolecules takes place. The temperature of the biomolecular sample is monitored and controlled by the integrated thermal sensor and the integrated heater. Once hybridization takes place, the change in electric condition (e.g. voltage, current and/or power) is recorded and identification of the molecule within biomolecular sample is made by utilizing an exterior reader.
Abstract:
The present invention is directed to devices and methods for manipulating polarizable analytes via dielectrophoresis to allow for improved detection of target analytes. Microfluidic devices (405) are configured such that the application of a voltage between field-generating electrodes (420, 421) results in the generation of an asymmetric electric field within the device (405). Some embodiments of the invention provide a physical constriction (410), and electrically floating conductive material (430) or a combination of the two techniques to generate an asymmetrical field. Using dielectrophoresis, target analytes are concentrated or separated from contaminant analytes and transported to a detection module (440).
Abstract:
An exemplary system and method for providing substantially uniform mixing of fluid phases, wherein the frequency of operation, flow velocities and/or device dimensions generally correspond to otherwise substantially diffusion limited applications, is disclosed as comprising inter alia: a mixing chamber; a plurality of electrodes (150) for generating an electric field; an electromagnet (200) for generating a magnetic field; and a controller for oscillating the electric field and the magnetic field in order to produce a periodic frequency-difference phase cycling of the electric and magnetic fields. Disclosed features and specifications may be variously controlled, adapted or otherwise optionally modified to improve mixing operation in any diffusion limited application. Exemplary embodiments of the present invention representatively provide for efficient mixing of fluid phases at relatively high frequencies and may be readily integrated with existing micro-scale technologies for the improvement of device package form factors, weights and other manufacturing and/or device performance metrics.