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    MEDICAL TAPE PREPARATION
    1.
    发明专利
    MEDICAL TAPE PREPARATION 未知

    公开(公告)号：HK1116099A1

    公开(公告)日：2008-12-19

    申请号：HK08105633

    申请日：2008-05-21

    Applicant: NIPRO PATCH CO LTD

    Inventor： KAWAMURA NAOHISA ,  SAWADA HIDENORI ,  KOBAYASHI TAKAYUKI

    IPC: A61K20060101 ,  A61L20060101 ,  C09J20060101

    Abstract: A medical tape preparation which comprises a support and, superposed on one side thereof in the following order, a pressure-sensitive adhesive layer and a release liner. The pressure-sensitive adhesive layer can contain a large amount of an oleophilic oily matter. The tape preparation is excellent in adhesion, cohesiveness, and stability even when no crosslinking agent is used. The pressure-sensitive adhesive layer in the medical tape preparation comprises a blend of two tacky polymers, which are a tacky polymer (A) comprising a copolymer obtained from 2-acetoacetoxyethyl methacrylate and other vinyl monomer(s) as constituent ingredients and a tacky polymer (B) comprising a copolymer which is obtained from a C 4-10 -alkyl (meth)acrylate and other vinyl monomer(s) as constituent ingredients and is different from the tacky polymer (A).

    Preparación de cinta médica
    2.
    发明专利
    Preparación de cinta médica 未知

    公开(公告)号：ES2416679T3

    公开(公告)日：2013-08-02

    申请号：ES05814768

    申请日：2005-12-12

    Applicant: NIPRO PATCH CO LTD

    Inventor： KAWAMURA NAOHISA ,  SAWADA HIDENORI ,  KOBAYASHI TAKAYUKI

    IPC: A61L15/58 ,  A61K9/70 ,  A61L15/22 ,  C09J7/02 ,  C09J133/08 ,  C09J133/14

    Abstract: Una preparación de cinta que tiene una capa de adhesivo sensible a la presión y un revestimiento de liberaciónlaminado en ese orden sobre una cara de un soporte, la preparación de cinta que está caracterizada porque el adhesivosensible a la presión de la capa de adhesivo sensible a la presión es una mezcla de dos adhesivos sensibles a la presión diferentes: (A) un polímero adhesivo A sensible a la presión que comprende un copolímero cuyos componentesconstituyentes comprenden éster de 2-acetoacetoxietil metacrilato y otro monómero vinílico, y (B) un polímero adhesivo B sensible a la presión que comprende un copolímero diferente del polímero adhesivoA sensible a la presión, cuyos componentes constituyentes comprenden un éster de alquil (met)acrilato con un grupoalquilo C4-10 y otro monómero vinílico, en la que el contenido del éster de 2-acetoacetoxietil metacrilato en el polímero adhesivo A sensible a lapresión es del 1%-50% en peso con respecto al peso del copolímero total del polímero adhesivo A sensible a la presión,y en la que la proporción del polímero adhesivo A sensible a la presión como componente (A) y del polímeroadhesivo B sensible a la presión como componente (B) es de 1:9-4:1.

    NONAQUEOUS ADHESIVE FOR MEDICINAL TAPE PREPARATION FOR PERCUTANEOUS ABSORPTION, MEDICINAL TAPE PREPARATION FOR PERCUTANEOUS ABSORPTION, AND PROCESS FOR PRODUCING THE SAME
    3.
    发明专利
    NONAQUEOUS ADHESIVE FOR MEDICINAL TAPE PREPARATION FOR PERCUTANEOUS ABSORPTION, MEDICINAL TAPE PREPARATION FOR PERCUTANEOUS ABSORPTION, AND PROCESS FOR PRODUCING THE SAME 未知

    公开(公告)号：HK1094677A1

    公开(公告)日：2007-04-04

    申请号：HK07100773

    申请日：2007-01-22

    Applicant: NIPRO PATCH CO LTD

    Inventor： KAWAMURA NAOHISA ,  SAWADA HIDENORI ,  KOBAYASHI TAKAYUKI

    IPC: A61K20100101 ,  A61K9/70

    Abstract: A nonaqueous pressure-sensitive adhesive for a medicinal tape preparation for percutaneous absorption comprising (a) a support, (b) a pressure-sensitive adhesive layer containing a drug and a nonaqueous pressure-sensitive adhesive and (c) a release film laminated in that order, and a medicinal tape preparation for percutaneous absorption comprising the adhesive. The nonaqueous pressure-sensitive adhesive may comprise a copolymer obtained by copolymerization of a (meth)acrylic monomer having an acetoacetyl group in the molecule and one or more monomers from among other (meth)acrylic monomers without acetoacetyl groups and copolymerizable vinyl monomers, in a nonaqueous solvent. Suitable (meth)acrylic monomers having an acetoacetyl group in the molecule are acetoacetoxyalkyl methacrylates, and especially 2-acetoacetoxyethyl methacrylate. The copolymer nonaqueous pressure-sensitive adhesive of the invention, comprising a (meth)acrylic monomer having an acetoacetyl group as a constituent monomer, is capable of containing large amounts of lipophilic oily substances in the pressure-sensitive adhesive layer, and during heat drying, the acetoacetyl groups undergo self-crosslinking to form a network structure as the solvent evaporates off, so that large amounts of oily substances such as the plasticizer can be included in the network structure. The pressure-sensitive adhesive of the invention uses no polyamine derivatives, isocyanate compounds, polyvalent metal chelate compounds, etc. as crosslinking agents, and therefore toxicity is not a concern and skin is not irritated. A medicinal tape preparation for percutaneous absorption of the invention has superior adhesive strength and cohesive strength, and is highly safe with low skin irritation. It also has excellent drug release and percutaneous absorption properties.

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