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公开(公告)号：WO2012139063A3
公开(公告)日：2012-12-27
申请号：PCT/US2012032629
申请日：2012-04-06
Applicant: OCULEVE INC , UNIV LELAND STANFORD JUNIOR , ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
IPC: A61N1/36
CPC classification number: A61N1/37205 , A61N1/0526 , A61N1/36046 , A61N1/37229
Abstract: Described here are stimulation systems and methods for stimulating one or more anatomical targets in a patient for treatment conditions such as dry eye. The stimulation system may include a controller and a micro stimulator. The components of the controller and micro stimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and micro stimulator may communicate wirelessly or via a wired connection. The micro stimulator may generate pulses from a signal received from the controller and apply the signal via one or more electrodes to an anatomical target. In some variations, the micro stimulator may include a passive generation circuit configured to generate a pulse based on a signal received from the controller.
Abstract translation: 这里描述了用于刺激患者中的一种或多种解剖靶的刺激系统和方法，用于诸如干眼症的治疗条件。 刺激系统可以包括控制器和微型刺激器。 控制器和微型激励器的组件可以在单个单元中或在单独的设备中实现。 当单独实现时，控制器和微型激励器可以无线地或经由有线连接进行通信。 微型刺激器可以从从控制器接收的信号产生脉冲，并通过一个或多个电极将信号施加到解剖靶上。 在一些变型中，微型激励器可以包括被配置为基于从控制器接收的信号产生脉冲的无源发生电路。
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公开(公告)号：AU2015335774A1
公开(公告)日：2017-05-18
申请号：AU2015335774
申请日：2015-10-22
Applicant: OCULEVE INC
Inventor： FRANKE MANFRED , LOUDIN JAMES DONALD , KUZMA JANUSZ , YUN PAUL TAEHYUN , ACKERMANN DOUGLAS MICHAEL
IPC: A61N1/36
Abstract: Described here are systems, devices, and methods for implanting a nasal stimulator into nasal tissue and electrically stimulating nasal tissue. In some variations, a nasal microstimulator implantation system may comprise an implantation tool and an implantable microstimulator. An implantation tool may comprise a shaft and features to releasably attach a microstimulator. A microstimulator may comprise a passive stimulation circuit and one or more electrodes. In other variations, a nasal implantation system may additionally comprise one or more additional devices, such as a controller, an electrical probe, and/or a dissection tool.
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公开(公告)号：AU2016201224A1
公开(公告)日：2016-03-24
申请号：AU2016201224
申请日：2016-02-26
Applicant: UNIV LELAND STANFORD JUNIOR , OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
IPC: A61N1/36
Abstract: Described here are stimulation systems and methods for stimulating one or more anatomical targets in a patient for treatment conditions such as dry eye. The stimulation system may include a controller and a microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a signal received from the controller and apply the signal via one or more electrodes to an anatomical target. In some variations, the microstimulator may include a passive generation circuit configured to generate a pulse based on a signal received from the controller. WO 2012/139063 PCT/US2012/032629 1608 ~ '"I 0) 1650- FIG. 16C
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公开(公告)号：CA2832463A1
公开(公告)日：2012-10-11
申请号：CA2832463
申请日：2012-04-06
Applicant: OCULEVE INC , UNIV LELAND STANFORD JUNIOR
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
Abstract: Described here are stimulation systems and methods for stimulating one or more anatomical targets in a patient for treatment conditions such as dry eye. The stimulation system may include a controller and a micro stimulator. The components of the controller and micro stimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and micro stimulator may communicate wirelessly or via a wired connection. The micro stimulator may generate pulses from a signal received from the controller and apply the signal via one or more electrodes to an anatomical target. In some variations, the micro stimulator may include a passive generation circuit configured to generate a pulse based on a signal received from the controller.
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公开(公告)号：AU2012239966B2
公开(公告)日：2015-11-26
申请号：AU2012239966
申请日：2012-04-06
Applicant: OCULEVE INC , UNIV LELAND STANFORD JUNIOR
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
Abstract: Described here are stimulation systems and methods for stimulating one or more anatomical targets in a patient for treatment conditions such as dry eye. The stimulation system may include a controller and a micro stimulator. The components of the controller and micro stimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and micro stimulator may communicate wirelessly or via a wired connection. The micro stimulator may generate pulses from a signal received from the controller and apply the signal via one or more electrodes to an anatomical target. In some variations, the micro stimulator may include a passive generation circuit configured to generate a pulse based on a signal received from the controller.
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Patent Agency Ranking
公开(公告)号：AU2015203275A1
公开(公告)日：2015-07-09
申请号：AU2015203275
申请日：2015-06-16
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health. WO 2014/172693 PCT/US2014/034733 100-% 118 0 o142
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公开(公告)号：AU2014253754A1
公开(公告)日：2015-02-26
申请号：AU2014253754
申请日：2014-04-18
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：AU2015335774B2
公开(公告)日：2020-07-16
申请号：AU2015335774
申请日：2015-10-22
Applicant: OCULEVE INC
Inventor： FRANKE MANFRED , LOUDIN JAMES DONALD , KUZMA JANUSZ , YUN PAUL TAEHYUN , ACKERMANN DOUGLAS MICHAEL
IPC: A61N1/36
Abstract: Described here are systems, devices, and methods for implanting a nasal stimulator into nasal tissue and electrically stimulating nasal tissue. In some variations, a nasal microstimulator implantation system may comprise an implantation tool and an implantable microstimulator. An implantation tool may comprise a shaft and features to releasably attach a microstimulator. A microstimulator may comprise a passive stimulation circuit and one or more electrodes. In other variations, a nasal implantation system may additionally comprise one or more additional devices, such as a controller, an electrical probe, and/or a dissection tool.
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公开(公告)号：AU2019201088B2
公开(公告)日：2020-07-09
申请号：AU2019201088
申请日：2019-02-15
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：ES2645204T3
公开(公告)日：2017-12-04
申请号：ES12768458
申请日：2012-04-06
Applicant: OCULEVE INC , UNIV LELAND STANFORD JUNIOR
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
Abstract: Sistema (2100) para tratar estados del ojo que comprende: un microestimulador implantable (2106, 3502, 4200) configurado para generar una señal de estimulación, que comprende un alojamiento (4202) que comprende un circuito de estimulación pasivo y una conexión interfacial; y una extensión flexible (4204) conectada al alojamiento y que comprende al menos un electrodo (4206), en el que la extensión flexible comprende un componente moldeado que tiene un grosor que es mayor que un grosor del alojamiento o menor que el grosor del alojamiento y que se estrecha hasta el grosor del alojamiento o que tiene un grosor que el igual que el grosor del alojamiento, y en el que el electrodo puede conectarse al circuito de estimulación pasivo a través de la conexión interfacial; un controlador portátil (2102, 2104) configurado para producir una señal de salida para proporcionar energía al microestimulador, en el que al menos uno de una amplitud, ancho de pulso o frecuencia de pulso de la señal de estimulación depende de al menos uno de una amplitud, ancho de pulso o frecuencia de pulso de la señal de salida; y un dispositivo de inserción (3500) configurado para sujetar de manera liberable el microestimulador cerca de un extremo distal del dispositivo de inserción.
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