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公开(公告)号：CA3022683A1
公开(公告)日：2017-11-09
申请号：CA3022683
申请日：2017-05-02
Applicant: OCULEVE INC
Inventor： FRANKE MANFRED , SENCHYNA DIANE MICHELLE , HAMILTON DANIEL N
IPC: A61N1/36
Abstract: Described here are devices, systems, and methods for treating meibomian gland disease and/or blepharitis by providing intranasal stimulation. Generally, the devices may deliver electrical stimulation to the nasal mucosa. Intranasal stimulation may unblock obstructed meibomian glands and increase the lipid content of tears, both acutely during stimulation and subsequent to intranasal stimulation. The methods may include an initial round of stimulation to unblock obstructed meibomian glands, and subsequent shorter rounds of stimulation to cause meibum secretion and maintain the open glands.
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公开(公告)号：AU2015203275A1
公开(公告)日：2015-07-09
申请号：AU2015203275
申请日：2015-06-16
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health. WO 2014/172693 PCT/US2014/034733 100-% 118 0 o142
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公开(公告)号：AU2014253754A1
公开(公告)日：2015-02-26
申请号：AU2014253754
申请日：2014-04-18
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：WO2014172693A2
公开(公告)日：2014-10-23
申请号：PCT/US2014034733
申请日：2014-04-18
Applicant: OCULEVE INC
Inventor： ACKERMAN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JNAUSZ , STIVERS CHRISTOPHER WILLIAM
CPC classification number: A61N1/0546 , A61F7/12 , A61H1/00 , A61H9/0071 , A61H21/00 , A61H23/02 , A61H23/0218 , A61H23/0245 , A61H23/0263 , A61H2201/0153 , A61H2201/0173 , A61H2201/0207 , A61H2201/0214 , A61H2201/025 , A61H2201/10 , A61H2201/165 , A61H2201/5002 , A61H2201/5005 , A61H2201/5015 , A61H2201/5035 , A61H2201/5038 , A61H2201/5043 , A61H2205/023 , A61H2205/024 , A61M31/00 , A61N1/0456 , A61N1/36014 , A61N1/36046 , A61N1/36071 , A61N1/36132 , A61N1/36146 , A61N1/3615 , A61N1/36171 , A61N1/36175 , A61N1/3787 , A61N7/00 , A61N2007/0043 , H02J7/0044
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
Abstract translation: 这里描述了通过向鼻腔或鼻窦组织提供刺激来治疗一种或多种病症（如干眼症）或改善眼部健康的装置，系统和方法。 通常，设备可以是手持式的或可植入的。 在一些变型中，手持装置可以具有刺激器主体和具有一个或多个鼻插入尖端的刺激器探针。 当装置和系统用于治疗干眼症时，可以刺激鼻或鼻窦组织以增加泪液产生，减少干眼症状和/或改善眼部表面的健康。
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公开(公告)号：AU2019201088B2
公开(公告)日：2020-07-09
申请号：AU2019201088
申请日：2019-02-15
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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Patent Agency Ranking
公开(公告)号：CA2965514A1
公开(公告)日：2016-04-28
申请号：CA2965514
申请日：2015-10-22
Applicant: OCULEVE INC
Inventor： LOUDIN JAMES DONALD , FRANKE MANFRED , HAMILTON DANIEL N , DORAISWAMY ANAND , ACKERMANN DOUGLAS MICHAEL
IPC: A61N1/36
Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.
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公开(公告)号：AU2014253754C1
公开(公告)日：2015-07-30
申请号：AU2014253754
申请日：2014-04-18
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：AU2015335772B2
公开(公告)日：2020-07-09
申请号：AU2015335772
申请日：2015-10-22
Applicant: OCULEVE INC
Inventor： LOUDIN JAMES DONALD , FRANKE MANFRED , HAMILTON DANIEL N , DORAISWAMY ANAND , ACKERMANN DOUGLAS MICHAEL
IPC: A61N1/36
Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.
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公开(公告)号：AU2019201088A1
公开(公告)日：2019-03-07
申请号：AU2019201088
申请日：2019-02-15
Applicant: OCULEVE INC
Inventor： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：AU2015335772A1
公开(公告)日：2017-05-18
申请号：AU2015335772
申请日：2015-10-22
Applicant: OCULEVE INC
Inventor： LOUDIN JAMES DONALD , FRANKE MANFRED , HAMILTON DANIEL N , DORAISWAMY ANAND , ACKERMANN DOUGLAS MICHAEL
IPC: A61N1/36
Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.
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