公开(公告)号：AT541237T

公开(公告)日：2012-01-15

申请号：AT02806828

申请日：2002-08-01

Applicant: OREGON STATE

Inventor： YAN MINGDI ,  BARTLETT MICHELE

IPC: B01J20/285 ,  G03F7/00 ,  B01J20/281 ,  B01J20/283 ,  C08K20060101 ,  C08K3/00 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N30/88 ,  G03F7/008 ,  G03F7/012 ,  G03F7/11 ,  H01L21/31

Abstract: Methods of adhering polymeric materials to a substrate, either directly or through linker molecules, are disclosed. Structures, for example microstructures, including microwells and arrays of microwells, may be readily formed using the methods. In some embodiments, microstructures formed completely from polymeric materials are provided, making it possible to tailor the chemical and physical properties of the microstructures. For example, microwells having a bottom comprising a polar polymeric material and well sides/top comprising a non-polar polymeric material are provided. Biochemical reagents may be easily delivered to such "smart wells" because the intrinsic attraction of the well bottom for the reagents and the intrinsic repulsion between the well sides/top combine to direct the reagents to the wells.

公开(公告)号：AU2002367868A1

公开(公告)日：2003-10-27

申请号：AU2002367868

申请日：2002-08-01

Applicant: OREGON STATE

Inventor： YAN MINGDI ,  BARTLETT MICHELE

IPC: B01J20/285 ,  B01J20/281 ,  B01J20/283 ,  C08K20060101 ,  C08K3/00 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N30/88 ,  H01L21/31

Abstract: Methods of adhering polymeric materials to a substrate, either directly or through linker molecules, are disclosed. Structures, for example microstructures, including microwells and arrays of microwells, may be readily formed using the methods. In some embodiments, microstructures formed completely from polymeric materials are provided, making it possible to tailor the chemical and physical properties of the microstructures. For example, microwells having a bottom comprising a polar polymeric material and well sides/top comprising a non-polar polymeric material are provided. Biochemical reagents may be easily delivered to such "smart wells" because the intrinsic attraction of the well bottom for the reagents and the intrinsic repulsion between the well sides/top combine to direct the reagents to the wells.

公开(公告)号：AU2002367868A8

公开(公告)日：2003-10-27

申请号：AU2002367868

申请日：2002-08-01

Applicant: OREGON STATE

Inventor： YAN MINGDI ,  BARTLETT MICHELE

IPC: B01J20/285 ,  G03F7/00 ,  B01J20/281 ,  B01J20/283 ,  C08K20060101 ,  C08K3/00 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N30/88 ,  G03F7/004 ,  H01L21/31

Abstract: Methods of adhering polymeric materials to a substrate, either directly or through linker molecules, are disclosed. Structures, for example microstructures, including microwells and arrays of microwells, may be readily formed using the methods. In some embodiments, microstructures formed completely from polymeric materials are provided, making it possible to tailor the chemical and physical properties of the microstructures. For example, microwells having a bottom comprising a polar polymeric material and well sides/top comprising a non-polar polymeric material are provided. Biochemical reagents may be easily delivered to such "smart wells" because the intrinsic attraction of the well bottom for the reagents and the intrinsic repulsion between the well sides/top combine to direct the reagents to the wells.

公开(公告)号：WO03087206A8

公开(公告)日：2005-03-17

申请号：PCT/US0224675

申请日：2002-08-01

Applicant: OREGON STATE ,  YAN MINGDI ,  BARTLETT MICHELE

Inventor： YAN MINGDI ,  BARTLETT MICHELE

IPC: B01J20/285 ,  B01J20/281 ,  B01J20/283 ,  C08K20060101 ,  C08K3/00 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N30/88 ,  H01L21/31 ,  C08K

CPC classification number: C40B60/14 ,  B01J2219/00432 ,  B01J2219/00443 ,  B01J2219/00531 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00619 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00711 ,  B01J2219/00722 ,  B01J2219/00725 ,  B82Y30/00 ,  C40B40/10 ,  G03F7/0035 ,  G03F7/008 ,  G03F7/012 ,  G03F7/11

Abstract: Methods of adhering polymeric materials to a substrate, either directly or through linker molecules, are disclosed. Structures, for example, microstructures, including microwells and arrays of microwells, may be readily formed using the methods. In some embodiments, microstructures formed completely from polymeric materials are provided, making it possible to tailor the chemical and physical properties of the microstructures. For example, microwells having a bottom comprising a polar polymeric material and well sides/top comprising a non-polar polymeric material are provided. Biochemical reagents may be easily delivered to such "smart wells" because the intrinsic attraction of the well bottom for the reagents and the intrinsic repulsion between the well sides/top combine to direct the reagents to the wells.

Abstract translation: 公开了将聚合物材料直接或通过连接分子粘附到基底上的方法。 可以使用这些方法容易地形成结构，例如微结构，包括微孔和微孔阵列。 在一些实施方案中，提供了由聚合材料完全形成的微结构，使得可以调整微结构的化学和物理性能。 例如，提供具有包含极性聚合物材料的底部的微孔和包含非极性聚合物材料的阱侧/顶部。 生物化学试剂可以很容易地传递到这种“智能井”，因为井底对于试剂的内在吸引力和阱侧/顶部之间的固有排斥结合起来将试剂引导到井。

公开(公告)号：EP1576040A4

公开(公告)日：2008-12-10

申请号：EP02806828

申请日：2002-08-01

Applicant: OREGON STATE

Inventor： YAN MINGDI ,  BARTLETT MICHELE

IPC: B01J20/285 ,  G03F7/00 ,  B01J20/281 ,  B01J20/283 ,  C08K20060101 ,  C08K3/00 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N30/88 ,  G03F7/008 ,  G03F7/012 ,  G03F7/11 ,  H01L21/31

CPC classification number: C40B60/14 ,  B01J2219/00432 ,  B01J2219/00443 ,  B01J2219/00531 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00619 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00711 ,  B01J2219/00722 ,  B01J2219/00725 ,  B82Y30/00 ,  C40B40/10 ,  G03F7/0035 ,  G03F7/008 ,  G03F7/012 ,  G03F7/11

Abstract: Methods of adhering polymeric materials to a substrate, either directly or through linker molecules, are disclosed. Structures, for example, microstructures, including microwells and arrays of microwells, may be readily formed using the methods. In some embodiments, microstructures formed completely from polymeric materials are provided, making it possible to tailor the chemical and physical properties of the microstructures. For example, microwells having a bottom comprising a polar polymeric material and well sides/top comprising a non-polar polymeric material are provided. Biochemical reagents may be easily delivered to such 'smart wells' because the intrinsic attraction of the well bottom for the reagents and the intrinsic repulsion between the well sides/top combine to direct the reagents to the wells.