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    THERAPEUTIC PLACENTAL COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE
    3.
    发明申请
    THERAPEUTIC PLACENTAL COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE 审中-公开
    治疗性成分组合物，制备方法和使用方法

    公开(公告)号：US20150010506A1

    公开(公告)日：2015-01-08

    申请号：US14272339

    申请日：2014-05-07

    Applicant: OSIRIS THERAPEUTICS, INC.

    Inventor： Timothy Jansen ,  Samson Tom ,  Alla Danilkovitch ,  Dana Yoo ,  Jaime Zerhusen ,  Gabriele Putz Todd ,  Amy Elizabeth Johnson

    IPC: A61K35/50 ,  A61K38/21 ,  A61K38/17 ,  A61K38/19 ,  A61K38/18 ,  A61K38/22

    CPC classification number: A61K35/50 ,  A01N1/0221 ,  A61K38/1754 ,  A61K38/1808 ,  A61K38/1825 ,  A61K38/1833 ,  A61K38/1841 ,  A61K38/1858 ,  A61K38/1866 ,  A61K38/193 ,  A61K38/212 ,  A61K38/22 ,  A61K38/57 ,  C12N5/0605 ,  C12N2501/115

    Abstract: This invention provides a therapeutic placental composition comprising placental cells and other placental components derived from placental tissue. A cryopreserved placental composition is also provided. The placental compositions can be used to stimulate and promote angiogenesis, reduce inflammation, and to reduce scar formation, among others. The placental tissue can optionally be an amnion, chorion, a trophoblast-depleted chorion, umbilical cord, Wharton's jelly, placental cotyledon, and/or maternal decidua. The placental composition of the present invention is useful in treating a patient with a tissue injury (e.g., wound or burn) by applying the placental composition to the injury or in close proximity. Placental compositions may also be used to promote or increase regeneration of tissue. Similar application is useful with ligament and tendon repair and for engraftment procedures such as bone engraftment.

    Abstract translation: 本发明提供包含胎盘细胞和源自胎盘组织的其它胎盘组分的治疗性胎盘组合物。 还提供了一种冷冻保存的胎盘组合物。 胎盘组合物可用于刺激和促进血管发生，减少炎症，并减少瘢痕形成等。 胎盘组织可以任选地是羊膜，绒毛膜，滋养层细胞的绒毛膜，脐带，沃顿的果冻，胎盘子叶和/或母体的蜕膜。 本发明的胎盘组合物可用于通过将胎盘组合物施用于损伤或紧邻来治疗患有组织损伤（例如伤口或烧伤）的患者。 胎盘组合物也可用于促进或增加组织再生。 类似的应用可用于韧带和腱修复以及植入手术如骨移植。

    THERAPEUTIC PRODUCTS COMPRISING VITALIZED PLACENTAL DISPERSIONS
    4.
    发明申请
    THERAPEUTIC PRODUCTS COMPRISING VITALIZED PLACENTAL DISPERSIONS 审中-公开
    包装化妆品专用分散剂的治疗产品

    公开(公告)号：US20140037598A1

    公开(公告)日：2014-02-06

    申请号：US14056101

    申请日：2013-10-17

    Applicant: Osiris Therapeutics, Inc.

    Inventor： Timothy Jansen ,  Samson Tom ,  Alla Danilkovitch ,  Dana Yoo ,  Jaime Zerhusen

    IPC: A61K35/50 ,  A61K38/39 ,  A61K38/57 ,  A61K38/18

    CPC classification number: A61K35/28 ,  A01N1/0221 ,  A61K35/50 ,  A61K38/1825 ,  A61K38/1841 ,  A61K38/39 ,  A61K38/57 ,  C12N5/0605 ,  C12N2500/02 ,  C12N2501/115 ,  C12N2502/025

    Abstract: This invention provides a fluid therapeutic placental product comprising placental cells and a placental dispersion comprising placental factors. The placental cells and the placental dispersion are derived from placental tissue. A placental tissue can optionally be an amnion, chorion, or a trophoblast-depleted chorion. The placental product of the present invention is useful in treating a patient with a tissue injury (e.g. wound or burn) by applying the placental product to the injury. Similar application is useful with ligament and tendon repair and for engraftment procedures such as bone engraftment.

    Abstract translation: 本发明提供了包含胎盘细胞的流体治疗性胎盘产物和包含胎盘因子的胎盘分散体。 胎盘细胞和胎盘分散体来源于胎盘组织。 胎盘组织可以任选地是羊膜，绒毛膜或消化滋养层的绒毛膜。 本发明的胎盘产品可用于通过将胎盘产品应用于损伤来治疗患有组织损伤（例如伤口或烧伤）的患者。 类似的应用可用于韧带和腱修复以及植入手术如骨移植。

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