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    SINGLE-MOLECULE REAL-TIME ANALYSIS OF PROTEIN SYNTHESIS
    1.
    发明申请
    SINGLE-MOLECULE REAL-TIME ANALYSIS OF PROTEIN SYNTHESIS 审中-公开
    单分子实时分析蛋白质合成

    公开(公告)号：WO2010144151A3

    公开(公告)日：2011-05-12

    申请号：PCT/US2010001692

    申请日：2010-06-11

    Applicant: PACIFIC BIOSCIENCES CALIFORNIA ,  FLUSBERG BENJAMIN ,  TURNER STEPHEN ,  KORLACH JONAS ,  SCHADT ERIC

    Inventor： FLUSBERG BENJAMIN ,  TURNER STEPHEN ,  KORLACH JONAS ,  SCHADT ERIC

    IPC: C12Q1/68

    CPC classification number: G01N33/542 ,  G01N33/6818 ,  Y10T436/13 ,  Y10T436/143333

    Abstract: The present invention is generally directed to compositions, methods, and systems for performing single-molecule, real-time analysis of analytical reactions in which protein synthesis is occurring. The ability to analyze such reactions provides an opportunity to study those reactions as well as to potentially identify factors and/or approaches for impacting such reactions, e.g., to either enhance, inhibit, or otherwise affect such reactions including, but not limited to, affecting the reaction rate, processivity, fidelity, duration, and the like.

    Abstract translation: 本发明一般涉及用于进行蛋白质合成发生的分析反应的单分子实时分析的组合物，方法和系统。 分析这些反应的能力提供了研究这些反应的机会，并且潜在地鉴定影响这些反应的因素和/或方法，例如增强，抑制或以其他方式影响这些反应，包括但不限于影响 反应速度，持续性，持续时间等。

    Real-time sequencing methods and systems
    2.
    发明专利
    Real-time sequencing methods and systems 未知

    公开(公告)号：AU2010245304B2

    公开(公告)日：2015-06-04

    申请号：AU2010245304

    申请日：2010-04-26

    Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

    Inventor： KORLACH JONAS ,  TURNER STEPHEN ,  SCHADT ERIC

    IPC: C12N15/10 ,  C12Q1/68

    Abstract: The present invention is generally directed to compositions, methods, and systems for performing single-molecule, real-time analysis of a variety of different biological reactions. The ability to analyze such reactions provides an opportunity to study those reactions as well as to potentially identify factors and/or approaches for impacting such reactions, e.g., to either enhance or inhibit such reactions. In certain preferred embodiments, RNA templates are used in single-molecule real-time sequencing reactions.

    REAL-TIME SEQUENCING METHODS AND SYSTEMS
    3.
    发明专利
    REAL-TIME SEQUENCING METHODS AND SYSTEMS 未知

    公开(公告)号：CA2760155A1

    公开(公告)日：2010-11-11

    申请号：CA2760155

    申请日：2010-04-26

    Applicant: PACIFIC BIOSCIENCES CALIFORNIA

    Inventor： KORLACH JONAS ,  TURNER STEPHEN ,  SCHADT ERIC

    IPC: C12Q1/68 ,  C12N15/10

    Abstract: The present invention is generally directed to compositions, methods, and systems for performing single-molecule, real-time analysis of a variety of different biological reactions. The ability to analyze such reactions provides an opportunity to study those reactions as well as to potentially identify factors and/or approaches for impacting such reactions, e.g., to either enhance or inhibit such reactions. In certain preferred embodiments, RNA templates are used in single-molecule real-time sequencing reactions.

    REAL-TIME SEQUENCING METHODS AND SYSTEMS
    5.
    发明申请
    REAL-TIME SEQUENCING METHODS AND SYSTEMS 审中-公开
    实时测序方法和系统

    公开(公告)号：WO2010129019A3

    公开(公告)日：2011-03-31

    申请号：PCT/US2010001236

    申请日：2010-04-26

    Applicant: PACIFIC BIOSCIENCES CALIFORNIA ,  KORLACH JONAS ,  TURNER STEPHEN ,  SCHADT ERIC

    Inventor： KORLACH JONAS ,  TURNER STEPHEN ,  SCHADT ERIC

    IPC: C12Q1/68 ,  C12N15/10

    CPC classification number: C12Q1/6869 ,  C12Q1/702 ,  C12Q2565/518 ,  C12Q2547/101

    Abstract: The present invention is generally directed to compositions, methods, and systems for performing single-molecule, real-time analysis of a variety of different biological reactions. The ability to analyze such reactions provides an opportunity to study those reactions as well as to potentially identify factors and/or approaches for impacting such reactions, e.g., to either enhance or inhibit such reactions. In certain preferred embodiments, RNA templates are used in single-molecule real-time sequencing reactions.

    Abstract translation: 本发明一般涉及用于进行各种不同生物反应的单分子实时分析的组合物，方法和系统。 分析这些反应的能力提供了研究这些反应以及潜在鉴定影响这些反应的因素和/或方法的机会，例如增强或抑制这种反应。 在某些优选实施方案中，RNA模板用于单分子实时测序反应。

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