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公开(公告)号:MA41827A
公开(公告)日:2018-01-30
申请号:MA41827
申请日:2016-03-24
Applicant: PHARMACYCLICS LLC
Inventor: BONNAUD THIERRY , GOLDMAN ERICK , MUNOZ GARCIA ALBERTO , SMYTH MARK STEPHEN , WORRALL CHRISTOPHER PETER
IPC: A61K31/519 , A61P35/00 , C07D487/04
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公开(公告)号:HK1249736A1
公开(公告)日:2018-11-09
申请号:HK18109250
申请日:2018-07-17
Applicant: PHARMACYCLICS LLC
Inventor: GOLDMAN ERICK , SMYTH MARK STEPHEN , BONNAUD THIERRY , SULEIMAN OSAMA , WORRALL CHRISTOPHER PETER
IPC: A61K20060101 , A61P20060101 , C07D20060101
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公开(公告)号:HK1248147A1
公开(公告)日:2018-10-12
申请号:HK18107889
申请日:2018-06-19
Applicant: PHARMACYCLICS LLC
Inventor: GOLDMAN ERICK , SMYTH MARK STEPHEN , BONNAUD THIERRY , MUNOZ GARCIA ALBERTO , WORRALL CHRISTOPHER PETER
IPC: A61P20060101 , A61K20060101 , C07D20060101
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公开(公告)号:AU2016243122A1
公开(公告)日:2017-10-19
申请号:AU2016243122
申请日:2016-03-25
Applicant: PHARMACYCLICS LLC
Inventor: GOLDMAN ERICK , SMYTH MARK STEPHEN , BONNAUD THIERRY , SULEIMAN OSAMA , WORRALL CHRISTOPHER PETER
IPC: C07D487/04 , A61K31/519 , A61P35/00
Abstract: Disclosed are co-crystals of the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the co-crystals, as well as methods of using co-crystals, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
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公开(公告)号:ES2590905T8
公开(公告)日:2020-12-09
申请号:ES13166272
申请日:2010-10-12
Applicant: PHARMACYCLICS LLC
Inventor: CHEN WEI , LOURY DAVID J , MODY TARAK D , VERNER ERIK , SMYTH MARK STEPHEN , LUO WENCHEN
IPC: C07D487/04 , A61K31/519 , A61P19/02 , A61P19/10
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公开(公告)号:MA41828A
公开(公告)日:2018-01-30
申请号:MA41828
申请日:2016-03-24
Applicant: PHARMACYCLICS LLC
Inventor: BONNAUD THIERRY , GOLDMAN ERICK , SMYTH MARK STEPHEN , SULEIMAN OSAMA , WORRALL CHRISTOPHER PETER
IPC: A61K31/519 , A61P35/00 , C07D487/04
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公开(公告)号:AU2016243116A1
公开(公告)日:2017-10-19
申请号:AU2016243116
申请日:2016-03-25
Applicant: PHARMACYCLICS LLC
Inventor: GOLDMAN ERICK , SMYTH MARK STEPHEN , BONNAUD THIERRY , MUNOZ GARCIA ALBERTO , WORRALL CHRISTOPHER PETER
IPC: C07D487/04 , A61K31/519 , A61P35/00
Abstract: Described herein are solvates of the Bruton's tyrosine kinase (Btk) inhibitor l-((R)-3-(4-amino- 3 -(4-phenoxyphenyl)- lH-pyrazolo[3,4-d]pyrimidin- 1 -yl)piperidin- 1 -yl)prop-2-en- 1 -one, including crystalline forms, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the solvates, as well as methods of using the solvates, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
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公开(公告)号:CA2981046A1
公开(公告)日:2016-10-06
申请号:CA2981046
申请日:2016-03-25
Applicant: PHARMACYCLICS LLC
Inventor: GOLDMAN ERICK , SMYTH MARK STEPHEN , BONNAUD THIERRY , SULEIMAN OSAMA , WORRALL CHRISTOPHER PETER
IPC: A61K31/519 , A61P35/00 , C07D487/04
Abstract: Disclosed are co-crystals of the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the co-crystals, as well as methods of using co-crystals, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
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公开(公告)号:HK1249737A1
公开(公告)日:2018-11-09
申请号:HK18109251
申请日:2018-07-17
Applicant: PHARMACYCLICS LLC
Inventor: GOLDMAN ERICK , SMYTH MARK STEPHEN , BONNAUD THIERRY , MUNOZ GARCIA ALBERTO , WORRALL CHRISTOPHER PETER
IPC: A61P20060101 , A61K20060101 , C07D20060101
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公开(公告)号:HK1248148A1
公开(公告)日:2018-10-12
申请号:HK18107890
申请日:2018-06-20
Applicant: PHARMACYCLICS LLC
Inventor: GOLDMAN ERICK , SMYTH MARK STEPHEN , BONNAUD THIERRY , SULEIMAN OSAMA , WORRALL CHRISTOPHER PETER
IPC: A61K20060101 , A61P20060101 , C07D20060101
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