公开(公告)号：DE602007005988D1

公开(公告)日：2010-06-02

申请号：DE602007005988

申请日：2007-02-12

Applicant: PHILIPS INTELLECTUAL PROPERTY

Inventor： BYSTROV DANIEL ,  NETSCH THOMAS ,  YOUNG STEWART

IPC: G06T17/40

Abstract: A function generator (MFG) formulates a query to a mapping database (DBM) based on a received planning geometry type (PGT) and receives corresponding function data (MFD) which is processed to create a function (MF). An evaluator (ELV) receives the function (MF) and an anatomical landmark set (LMS) and determines a computed planning geometry (CPG). A user interface (UI) displays a survey image (IMG), the landmark set (LMS), and the computer planning geometry (CPG) and allows the user to adjust the landmark set and/or the computer program geometry. A record generator (RG) creates a new record from the user adjusted landmarks (ULMS) and the user adjusted computer planning geometries (UPG) and loads the new records (NR) into the mapping database (DBM).

公开(公告)号：WO2009019630A3

公开(公告)日：2009-08-13

申请号：PCT/IB2008053042

申请日：2008-07-29

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  PEKAR VLADIMIR ,  BYSTROV DANIEL

Inventor： PEKAR VLADIMIR ,  BYSTROV DANIEL

IPC: G06T7/00

CPC classification number: G06K9/3216 ,  A61B6/503 ,  A61B6/504 ,  G06K2209/05 ,  G06T7/32 ,  G06T7/33 ,  G06T7/337 ,  G06T2207/10072 ,  G06T2207/20128 ,  G06T2207/30012

Abstract: The invention relates to a system (100) for registering an atlas image from an atlas of multidimensional images with an objective image, the system comprising a generation unit (105) for generating a candidate transformation for transforming a first region of the atlas image, a transformation unit (110) for transforming the first region of the atlas image using the candidate transformation, a similarity unit (120) for computing a measure of similarity of the transformed first region of the atlas image and a corresponding first region of the objective image, an evaluation unit (130) for evaluating the candidate transformation using a criterion based on the computed measure of similarity and determining an optimal transformation based on the evaluation of the candidate transformation, an extension unit (140) for extending the optimal transformation of the first region of the atlas image to a second region of the atlas image, wherein the second region comprises the first region, thereby creating a registration transformation and a registration unit (150) for transforming the second region using the registration transformation, thereby registering the atlas image with the objective image. Advantageously, the system (100) does not require setting landmark positions in the objective image. A further advantage of the system (100) is that since the similarity measure is computed locally, i.e., based on the first region of the atlas image, the registration is fast and thus attractive for clinical use.

Abstract translation: 本发明涉及一种用于将来自多维图像图集的阿特拉斯图像与目标图像配准的系统（100），所述系统包括：生成单元（105），用于生成用于变换所述图谱图像的第一区域的候选变换; 变换单元（110），用于使用所述候选变换来变换所述图谱图像的第一区域;相似度单元（120），其用于计算所述图谱图像的变换后的第一区域和所述目标图像的对应第一区域的相似性度量; 评估单元（130），用于使用基于所计算的相似性度量的准则评估所述候选变换并且基于所述候选变换的所述评估来确定最优变换;扩展单元（140），用于扩展所述第一区域的最优变换 将所述图谱图像的所述第二区域与所述图谱图像的第二区域相比较，其中所述第二区域包括所述第一区域，由此c 重新配准注册变换和配准单元（150），以使用配准变换来变换第二区域，由此将图谱图像与目标图像配准。 有利地，系统（100）不需要在目标图像中设置地标位置。 系统（100）的另一个优点是由于相似性度量是局部计算的，即基于图谱图像的第一区域，所以配准速度快，因此对于临床使用具有吸引力。

公开(公告)号：WO2008065598A3

公开(公告)日：2009-05-14

申请号：PCT/IB2007054788

申请日：2007-11-26

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  YOUNG STEWART ,  BYSTROV DANIEL ,  NETSCH THOMAS ,  KAUS MICHAEL ,  PEKAR VLADIMIR

Inventor： YOUNG STEWART ,  BYSTROV DANIEL ,  NETSCH THOMAS ,  KAUS MICHAEL ,  PEKAR VLADIMIR

IPC: G06T7/60

CPC classification number: G06T7/149 ,  G06T7/12 ,  G06T7/70 ,  G06T2207/30016

Abstract: The invention relates to a method for data processing. At stage 3 the position of the reference object in the reference image and its relation to a set of reference landmarks in the reference image is established at step 6. In order to enable this, the reference imaging of learning examples may be performed at step 2 and each reference image may be analyzed at step 4, the results may be stored in a suitably arranged database. In order to process the image under consideration, the image is accessed at step 11, the suitable landmark corresponding to the reference landmark in the reference image is identified at step 13 and the spatial relationship established at step 6 is applied to the landmark thereby providing the initial position of the object in the actual image. In case when for the object an imaging volume is selected, the method 1 according to the invention follows to step 7, whereby the scanning 17 is performed within the boundaries given by the thus established scanning volume. In case when for the object a model representative of the target is selected, the method 1 follows to the image segmentation step 19, whereby a suitable segmentation is performed. In case when for the model a deformable model is selected, the segmentation is performed by deforming the model thereby providing spatial boundaries of the target area. The invention further relates to an apparatus and a computer program for image processing.

Abstract translation: 本发明涉及一种数据处理方法。 在阶段3，在步骤6中建立参考图像中的参考对象的位置及其与参考图像中的一组参考标记的关系。为了实现这一点，可以在步骤2执行学习示例的参考成像 并且可以在步骤4分析每个参考图像，结果可以存储在适当布置的数据库中。 为了处理所考虑的图像，在步骤11访问图像，在步骤13识别与参考图像中的参考标记相对应的合适地标，并将在步骤6建立的空间关系应用于地标，从而提供 物体在实际图像中的初始位置。 在对于物体选择成像体积的情况下，根据本发明的方法1遵循步骤7，由此在由这样建立的扫描体积给出的边界内执行扫描17。 在针对对象的情况下，选择了表示目标的模型，则对图像分割步骤19进行方法1，由此执行适当的分割。 在为模型选择可变形模型的情况下，通过使模型变形从而提供目标区域的空间边界来执行分割。 本发明还涉及一种用于图像处理的装置和计算机程序。

公开(公告)号：WO2007031954A3

公开(公告)日：2009-05-07

申请号：PCT/IB2006053278

申请日：2006-09-14

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  BYSTROV DANIEL ,  PEKAR VLADIMIR

Inventor： BYSTROV DANIEL ,  PEKAR VLADIMIR

IPC: G06T7/00

CPC classification number: G06T7/38 ,  G06T7/33

Abstract: The invention relates to a registration method (100) of registering a second image dataset with a first image dataset on the basis of a set of landmarks, said registration method (100) comprising a weight-assigning step (125) for assigning a weight to each coordinate of each landmark from the set of landmarks and a registering step (145) for registering the second image dataset with the first image dataset on the basis of the weight assigned to the each coordinate. Choosing an appropriate set of landmarks and assigning an appropriate weight to each coordinate of each landmark from the set of landmarks can be used for optimizing selected displacements of a designated anatomical structure comprising elastic bodies and/or a plurality of independent rigid bodies in a sequence of image datasets. This enables rendering a sequence of views wherein the designated anatomical structure is not displaced off a viewing plane and/or a selected part of the designated anatomical structure is not displaced in a viewing plane.

Abstract translation: 本发明涉及一种基于一组地标登记第一图像数据集的第二图像数据集的登记方法（100），所述登记方法（100）包括权重分配步骤（125），用于将权重分配给 基于所述一组地标的每个地标的每个坐标和用于根据分配给每个坐标的权重将第二图像数据集与第一图像数据集进行登记的登记步骤（145）。 可以使用合适的地标集合并从该地标集合为每个地标的每个坐标分配适当的权重，以优化包括弹性体和/或多个独立刚体的指定解剖结构的选定位移 图像数据集。 这使得能够呈现一系列视图，其中指定的解剖结构不会离开观察平面，和/或指定的解剖结构的选定部分不会在观察平面中移位。

公开(公告)号：WO2010113050A3

公开(公告)日：2010-12-02

申请号：PCT/IB2010050893

申请日：2010-03-02

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  PEKAR VLADIMIR ,  BYSTROV DANIEL

Inventor： PEKAR VLADIMIR ,  BYSTROV DANIEL

IPC: G06F19/00 ,  A61N5/10

CPC classification number: A61N5/103 ,  G06F19/3481

Abstract: When delineating anatomical structures in a medical image of a patient for radiotherapy planning, a processor (18) detects landmarks (24) in a low-resolution image (e.g., MRI or low-dose CT) and maps the detected landmarks to reference landmarks (28) in a reference contour of the anatomical structure. The mapped landmarks facilitate adjusting the reference contour to fit the anatomical structure. The adjusted reference contour data is transformed and applied to a second image using a thin-plate spline, and the adjusted high-resolution image is used for radiotherapy planning.

Abstract translation: 当在放射治疗计划的患者的医疗图像中描绘解剖结构时，处理器（18）检测低分辨率图像（例如，MRI或低剂量CT）中的界标（24），并将检测到的界标映射到参考界标 28）在解剖结构的参考轮廓中。 映射的界标便于调整参考轮廓以适应解剖结构。 调整后的参考轮廓数据被转换并且使用薄板样条线应用于第二图像，并且调整后的高分辨率图像用于放射治疗计划。

公开(公告)号：WO2007034346A3

公开(公告)日：2008-12-04

申请号：PCT/IB2006053141

申请日：2006-09-07

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  COCOSCO CHRISTIAN A ,  NETSCH THOMAS ,  BYSTROV DANIEL ,  YOUNG STEWART

Inventor： COCOSCO CHRISTIAN A ,  NETSCH THOMAS ,  BYSTROV DANIEL ,  YOUNG STEWART

IPC: G06T5/00 ,  G06T7/00

CPC classification number: G06T7/0012 ,  G06T7/11 ,  G06T7/149 ,  G06T2207/10072 ,  G06T2207/20081 ,  G06T2207/30004

Abstract: The invention relates to a method 1 of image segmentation where in step 2 a prior model representative of a structure conceived to be segmented in an image is accessed. Preferably, the image comprises a medical diagnostic image. Still preferably, the medical diagnostic image is prepared in a DICOM format, whereby supplementary information is stored besides diagnostic data. In these cases the method 1 according to the invention advantageously proceeds to step 3, where the supplementary information is extracted from electronic file 5, comprising for example suitable patient-related information 5a and/or suitable structure-related information 5b. Examples of the patient-related information comprise a patient's age, sex, group, etc., whereas examples of the structure-related information may comprise an anatomic location of the structure, such as rectum, bladder, lung etc, or the suspected / diagnosed pathology of the patient. In an alternative embodiment of the method 1 according to the invention, the supplementary information is provided by a human operator in step 7, where he can enter suitable supplementary information 9a, 9b using a user interface 9. When the supplementary information is loaded, the method 1 according to the invention proceeds to step 4 in which the prior model is being changed using the supplementary information yielding a further model. In step 6 the method 1 performs the image segmentation using the thus obtained further model and in step 8 the results of the segmentation step may be visualized on a suitable viewer.

Abstract translation: 本发明涉及一种图像分割的方法1，其中在步骤2中，访问代表在图像中被分割的结构的先前模型。 优选地，图像包括医学诊断图像。 更优选地，以DICOM格式准备医疗诊断图像，除了诊断数据之外还存储补充信息。 在这些情况下，根据本发明的方法1有利地进行到步骤3，其中从电子文件5中提取补充信息，包括例如合适的患者相关信息5a和/或合适的结构相关信息5b。 患者相关信息的示例包括患者的年龄，性别，组等，而结构相关信息的实例可以包括结构的解剖位置，例如直肠，膀胱，肺等或疑似/诊断的 患者病理。 在根据本发明的方法1的替代实施例中，补充信息由人类操作者在步骤7中提供，其中他可以使用用户界面9输入合适的补充信息9a，9b。当补充信息被加载时， 根据本发明的方法1进行到步骤4，其中使用产生另外的模型的补充信息来改变现有模型。 在步骤6中，方法1使用由此获得的另外的模型执行图像分割，并且在步骤8中，分割步骤的结果可以在合适的观看者上可视化。

公开(公告)号：WO2008007281A3

公开(公告)日：2008-06-19

申请号：PCT/IB2007052505

申请日：2007-06-28

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  BYSTROV DANIEL ,  PEKAR VLADIMIR ,  YOUNG STEWART ,  BERGMANS CORNELIS J F M ,  VAN MUISWINKEL ARIANNE

Inventor： BYSTROV DANIEL ,  PEKAR VLADIMIR ,  YOUNG STEWART ,  BERGMANS CORNELIS J F M ,  VAN MUISWINKEL ARIANNE

IPC: G06T7/00 ,  G01R33/54

CPC classification number: G01R33/54 ,  G01R33/543 ,  G06T7/74 ,  G06T2207/30004 ,  G06T2207/30244

Abstract: The invention relates to a method, an apparatus and a computer program for transferring scan geometry between a first region and a second region, similar to the first region. In the method according to the invention the first region and the second region are being identified (4), preferably in the overview image, followed by determination (6) of the first scan geometry corresponding to the first region. Then, the first scan geometry is being transferred into the second scan geometry corresponding to the second region, whereby information on geometrical correspondence between the first region and the second region is used. Preferably, the step of transferring comprises establishing corresponding mappings between similar regions and their respective scan geometries.

Abstract translation: 本发明涉及用于在第一区域和第二区域之间传送扫描几何的方法，装置和计算机程序，类似于第一区域。 在根据本发明的方法中，优选地在概览图像中识别（4）第一区域和第二区域，随后确定（6）对应于第一区域的第一扫描几何图形。 然后，将第一扫描几何图形转移到对应于第二区域的第二扫描几何图形中，由此使用关于第一区域和第二区域之间的几何对应关系的信息。 优选地，转移步骤包括在相似区域和它们各自的扫描几何结构之间建立对应的映射。

公开(公告)号：WO2006013499A8

公开(公告)日：2006-04-27

申请号：PCT/IB2005052404

申请日：2005-07-19

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  SPRINGORUM RUDOLF ,  MEETZ KIRSTEN ,  VISSER FREDERIK ,  BYSTROV DANIEL

Inventor： SPRINGORUM RUDOLF ,  MEETZ KIRSTEN ,  VISSER FREDERIK ,  BYSTROV DANIEL

IPC: G06T11/00 ,  G06T7/60

CPC classification number: G06T7/68 ,  G06T7/80 ,  G06T2207/30004

Abstract: The apparatus (1) comprises an input (2) for receiving a suitable source image data of an object. The core of the apparatus (1) is formed by a control unit (4) which is arranged to load image data from the input (2) and determine a spatial position and orientation of a portion of the object and to automatically calculate actual parameters (4a) of the imaging geometry based on said position and orientation and using default parameters if the imaging geometry, selected by the control unit (4) in accordance with the portion of the object. The apparatus (1) further comprises a storage unit (8) arranged to store at least one set of default parameters of the imaging geometry, which may be representative of an imaging protocol. The working memory (6) typically holds the (parts of) image data being processed and the instructions for the suitable image processing means used for processing those parts of the image data. The apparatus (1) according to the invention comprises a recognition module (7) arranged to determine a spatial position and orientation of the portion of the object with respect to a coordinate system of an imaging apparatus conceived to use the actual parameters of the imaging geometry provided by the apparatus (1). When the position and orientation (7a) of the portion of the object with respect to the coordinate system of the data acquisition module is established, the control unit calculates actual parameters (4) of the imaging geometry based on a suitable matching between the spatial position and orientation (7a) of the portion of the object conceived to be imaged and the default parameters of the imaging geometry (3). Preferably, the apparatus (1) further comprises a suitably arranged user interface (5) for allowing an adjustment of automatically established actual parameters of the imaging geometry by a user. Preferably, the output (9) comprises a result of the automatic planning of the imaging geometry, which may be directly converted into a suitable control signal for the data acquisition module and/or be made available in a suitable form for archiving purposes. The invention further relates to an imaging system, a method and a computer program for automatically generating scan parameters.

Abstract translation: 装置（1）包括用于接收对象的适当源图像数据的输入（2）。 装置（1）的核心由控制单元（4）形成，控制单元（4）被布置成从输入（2）加载图像数据，并确定对象的一部分的空间位置和方位并自动计算实际参数（ 基于所述位置和取向的成像几何的图4a），并且如果由控制单元（4）根据对象的部分选择的成像几何形状使用默认参数。 装置（1）还包括存储单元（8），其被设置为存储成像几何的至少一组默认参数，其可以代表成像协议。 工作存储器（6）通常保存被处理的图像数据的（部分）和用于处理图像数据的那些部分的合适的图像处理装置的指令。 根据本发明的装置（1）包括识别模块（7），该识别模块（7）被布置成确定对象的部分相对于使用成像几何的实际参数构思的成像装置的坐标系的空间位置和取向 由装置（1）提供。 当物体的相对于数据采集模块的坐标系的部分的位置和方向（7a）被建立时，控制单元基于空间位置之间的适当匹配来计算成像几何的实际参数（4） 和被摄体成像对象的部分的取向（7a）和成像几何（3）的默认参数。 优选地，装置（1）还包括适当布置的用户界面（5），用于允许用户自动建立成像几何的实际参数的调整。 优选地，输出（9）包括成像几何的自动计划的结果，其可以被直接转换成用于数据获取模块的合适的控制信号和/或以适当的形式可用于归档目的。 本发明还涉及一种用于自动生成扫描参数的成像系统，方法和计算机程序。

公开(公告)号：WO2012176085A3

公开(公告)日：2013-03-07

申请号：PCT/IB2012052818

申请日：2012-06-05

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  BYSTROV DANIEL ,  VIK TORBJOERN ,  SCHULZ HEINRICH

Inventor： BYSTROV DANIEL ,  VIK TORBJOERN ,  SCHULZ HEINRICH

IPC: G06T7/00 ,  G06F9/44

CPC classification number: G06T15/00 ,  G06F19/321 ,  G06F19/3406 ,  G06T7/0012 ,  G16H40/63

Abstract: The invention relates to an image display apparatus for displaying an image like a three-dimensional medical image of an object. A template providing unit (3) provides a template defining display parameters for displaying the image based on anatomical features of the object, and an anatomical feature detecting unit (4) detects an anatomical feature in the image. A display parameter determining unit (5) determines a display parameter defining, for example, a desired view, based on the detected anatomical feature and the template, and a display unit (8) displays the image by displaying, for example, the desired view, in accordance with the determined display parameter. This allows the image display apparatus to show the image on the display in a desired usual way as defined by the template, even if in the originally provided image the object is shown in an unusual way.

Abstract translation: 本发明涉及一种用于显示像物体的三维医学图像的图像的图像显示装置。 模板提供单元（3）提供定义用于基于对象的解剖特征显示图像的显示参数的模板，以及解剖特征检测单元（4）检测图像中的解剖特征。 显示参数确定单元（5）基于检测到的解剖特征和模板来确定定义例如期望视图的显示参数，并且显示单元（8）通过显示例如期望视图来显示图像 ，根据确定的显示参数。 这允许图像显示装置以由模板定义的所需通常的方式在显示器上显示图像，即使在原始提供的图像中，对象以异常方式示出。

公开(公告)号：WO2012017375A2

公开(公告)日：2012-02-09

申请号：PCT/IB2011053411

申请日：2011-08-01

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  BYSTROV DANIEL ,  SCHADEWALDT NICOLE ,  SCHULZ HEINRICH ,  VIK TORBJOERN ,  KUMAR PRASHANT ,  MALLYA YOGISHA

Inventor： BYSTROV DANIEL ,  SCHADEWALDT NICOLE ,  SCHULZ HEINRICH ,  VIK TORBJOERN ,  KUMAR PRASHANT ,  MALLYA YOGISHA

IPC: G06T19/00

CPC classification number: G06T15/00 ,  G06T7/10 ,  G06T7/11 ,  G06T7/149 ,  G06T19/20 ,  G06T2207/10072 ,  G06T2210/41 ,  G06T2219/2021

Abstract: When segmenting a surface mesh diagnostic image, invertible transformations are facilitated by adjusting a Gaussian kernel size on the fly. Kernel size is adjusted as a function of distance traveled by a cursor during user selection of a contour to be adjusted. Additionally, surface mesh resolution is increased by iteratively subdividing mesh triangles (242) in the vicinity of a user-selected contour in a surface mesh (100, 220, 240, 318) until every pixel or voxel contains at least one triangle vertex. A fuzzy line change (FLC) algorithm (332) is then executed to snap the nearest mesh contour to a user- indicated position.

Abstract translation: 当分割表面网格诊断图像时，通过在飞行中调整高斯内核大小来促进可逆转换。 在用户选择要调整的轮廓的过程中，内核大小作为光标行进的距离的函数进行调整。 此外，通过在表面网格（100,220,240,318）中的用户选择的轮廓附近迭代地分割网格三角形（242）直到每个像素或体素包含至少一个三角形顶点，来增加表面网格分辨率。 然后执行模糊线变化（FLC）算法（332）以将最近的网格轮廓捕捉到用户指示的位置。