公开(公告)号：DE69524238T2

公开(公告)日：2002-07-18

申请号：DE69524238

申请日：1995-09-04

Applicant: PHOTOCURE ASA OSLO OSLO

Inventor： BERG KRISTIAN ,  SANDVIK KIRSTEN ,  MOAN JOHAN

IPC: A61K47/00 ,  A61K41/00 ,  A61K47/48

Abstract: The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.

公开(公告)号：DE69524238D1

公开(公告)日：2002-01-10

申请号：DE69524238

申请日：1995-09-04

Applicant: PHOTOCURE ASA OSLO OSLO

Inventor： BERG KRISTIAN ,  SANDVIK KIRSTEN ,  MOAN JOHAN

IPC: A61K47/00 ,  A61K41/00 ,  A61K47/48

Abstract: The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.