公开(公告)号：EP1737386A4

公开(公告)日：2012-01-04

申请号：EP05736870

申请日：2005-04-18

Applicant: PORTOLA PHARM INC

Inventor： ANDRE PATRICK ,  PHILLIPS DAVID R ,  HOMCY CHARLES

IPC: A61F2/02 ,  A61K31/473 ,  A61K31/4745 ,  A61K31/52 ,  A61L31/10 ,  A61L31/16

CPC classification number: A61K31/473 ,  A61K31/4745 ,  A61K31/52 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L2300/434

公开(公告)号：AU2005235289A1

公开(公告)日：2005-11-03

申请号：AU2005235289

申请日：2005-04-18

Applicant: PORTOLA PHARM INC

Inventor： ANDRE PATRICK ,  HOMCY CHARLES ,  PHILLIPS DAVID R

IPC: A61K31/4745 ,  A61F2/02 ,  A61K31/473 ,  A61K31/52

Abstract: The present invention provides novel compositions and methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient undergoing a vascular intervention. More particularly, the present invention provides intravascular devices coated with one or more spleen tyrosine kinase (Syk) inhibitors. Methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient by treatment with such intravascular devices are also provided. In addition, the present invention provides methods for treating sickle cell disease using Syk inhibitors.

公开(公告)号：AU2005235289B2

公开(公告)日：2010-10-28

申请号：AU2005235289

申请日：2005-04-18

Applicant: PORTOLA PHARM INC

Inventor： ANDRE PATRICK ,  HOMCY CHARLES ,  PHILLIPS DAVID R

IPC: A61K31/4745 ,  A61F2/02 ,  A61K31/473 ,  A61K31/52

Abstract: The present invention provides novel compositions and methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient undergoing a vascular intervention. More particularly, the present invention provides intravascular devices coated with one or more spleen tyrosine kinase (Syk) inhibitors. Methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient by treatment with such intravascular devices are also provided. In addition, the present invention provides methods for treating sickle cell disease using Syk inhibitors.

公开(公告)号：CA2562734A1

公开(公告)日：2005-11-03

申请号：CA2562734

申请日：2005-04-18

Applicant: PORTOLA PHARM INC

Inventor： ANDRE PATRICK ,  PHILLIPS DAVID R ,  HOMCY CHARLES

IPC: A61F2/02 ,  A61K31/473 ,  A61K31/4745 ,  A61K31/52

Abstract: The present invention provides novel compositions and methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient undergoing a vascul ar intervention. More particularly, the present invention provides intravascula r devices coated with one or more spleen tyrosine kinase (Syk) inhibitors. Methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient by treatment with such intravascular devices are also provided. In addition, the present invention provides methods for treating sickle cell disease using Syk inhibitors.