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公开(公告)号：AU2008247439A1
公开(公告)日：2008-11-13
申请号：AU2008247439
申请日：2008-05-02
Applicant: PORTOLA PHARM INC
Inventor： HOMCY CHARLES J , ANDRE PATRICK , PHILLIPS DAVID R
IPC: C12N9/02
Abstract: The present invention provides new methods of treating thrombosis and cardiovascular diseases using of antithrombotic agents, as well as methods of determining therapeutically effective amounts of antithrombotic agents and unit dose formulations thereof.
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2.发明公开USE OF TP MODULATORS FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS IN ASPIRIN SENSITIVE AND OTHER POPULATIONS 审中-公开TP调节剂用于治疗心血管疾病的阿司匹林敏感数据和其它人群治疗
公开(公告)号：EP2144999A4
公开(公告)日：2010-06-16
申请号：EP08747593
申请日：2008-05-02
Applicant: PORTOLA PHARM INC
Inventor： PHILLIPS DAVID R , ANDRE PATRICK , HOMCY CHARLES J
CPC classification number: A61K31/422 , A61K31/20 , A61K31/405 , A61K31/4406 , A61K31/444 , A61K45/06
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公开(公告)号：CA2688317A1
公开(公告)日：2008-11-13
申请号：CA2688317
申请日：2008-05-02
Applicant: PORTOLA PHARM INC
Inventor： ANDRE PATRICK , PHILLIPS DAVID R , HOMCY CHARLES J
IPC: A61K31/4365 , A61K31/34 , A61K31/352 , A61K31/405 , A61K31/421 , A61K31/4406 , A61K31/616 , A61P7/02 , A61P9/00 , C12N9/02 , C12Q1/00
Abstract: The present invention provides methods and compositions useful in the tre atment or prevention of cardiovascular disorders in individuals for whom the rapy with a COX-1 enzyme inhibitor is not feasible due to sensitivity, intol erance, or resistance to the inhibitor. Additionally, the invention provides methods of treating cardiovascular disorders in an individual who is receiv ing a therapeutically effective dose of a TP modulator and is instructed or advised to avoid and/or not to take aspirin or another COX-1 inhibitor.
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公开(公告)号：MX2009011745A
公开(公告)日：2010-02-12
申请号：MX2009011745
申请日：2008-05-02
Applicant: PORTOLA PHARM INC
Inventor： PHILLIPS DAVID R , ANDRE PATRICK , HOMCY CHARLES J
IPC: C12N9/02
Abstract: La presente invención proporciona métodos y composiciones útiles en el tratamiento o prevención de trastornos cardiovasculares en individuos para quienes no es factible la terapia con un inhibidor de enzima COX-1, debido a sensibilidad, intolerancia, o resistencia al inhibidor. Adicionalmente, la invención proporciona métodos para tratar trastornos cardiovasculares en un individuo quien está recibiendo una dosis terapéuticamente efectiva de un modulador de TP y se instruye o aconseja evitar y/o no tomar aspirina u otro inhibidor de COX-1.
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