公开(公告)号：EP1667989A4

公开(公告)日：2008-08-20

申请号：EP04785303

申请日：2004-09-29

Applicant: PORTOLA PHARM INC

Inventor： SCARBOROUGH ROBERT M ,  KANE-MAGUIRE KIM A ,  MARLOWE CHARLES K ,  SMYTH MARK S ,  ZHANG XIAOMING

IPC: C07D401/02 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/506 ,  C07D217/24 ,  C07D401/04 ,  C07D409/12

CPC classification number: C07D409/14 ,  C07D217/24 ,  C07D401/04 ,  C07D409/12

公开(公告)号：CA2539882A1

公开(公告)日：2005-04-21

申请号：CA2539882

申请日：2004-09-29

Applicant: PORTOLA PHARM INC

Inventor： MARLOWE CHARLES K ,  KANE-MAGUIRE KIM A ,  SMYTH MARK S ,  SCARBOROUGH ROBERT M ,  ZHANG XIAOMING

IPC: C07D401/02 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/506 ,  C07D217/24 ,  C07D401/04 ,  C07D409/12

Abstract: Isoquinolinone compounds are provided that are useful for the inhibition of ADP-platelet aggregation, particularly in the treatment of thrombosis and thrombosis related conditions or disorders.

公开(公告)号：MXPA06003625A

公开(公告)日：2006-08-11

申请号：MXPA06003625

申请日：2004-09-29

Applicant: PORTOLA PHARM INC

Inventor： SMYTH MARK S

IPC: A61K31/47 ,  A61K31/4709 ,  A61K31/506 ,  C07D217/24 ,  C07D401/02 ,  C07D401/04 ,  C07D409/12

Abstract: Se proporcionan compuestos de isoquinolinona que son utiles para la inhibicion de agregacion de plaquetas-ADP, particularmente en el tratamiento de trombosis y condiciones o desordenes relacionados con trombosis.

公开(公告)号：AU2004279809B2

公开(公告)日：2010-07-15

申请号：AU2004279809

申请日：2004-09-29

Applicant: PORTOLA PHARM INC

Inventor： MARLOWE CHARLES K ,  SMYTH MARK S ,  KANE-MAGUIRE KIM A ,  ZHANG XIAOMING ,  SCARBOROUGH ROBERT M

IPC: C07D217/24 ,  A61K31/17 ,  A61K31/381 ,  A61K31/435 ,  A61K31/4709 ,  A61K31/506 ,  A61P9/00 ,  A61P9/10 ,  C07D401/04 ,  C07D409/12

Abstract: Isoquinolinone compounds are provided that are useful for the inhibition of ADP-platelet aggregation, particularly in the treatment of thrombosis and thrombosis related conditions or disorders.

公开(公告)号：AU2004279809A1

公开(公告)日：2005-04-21

申请号：AU2004279809

申请日：2004-09-29

Applicant: PORTOLA PHARM INC

Inventor： MARLOWE CHARLES K ,  SMYTH MARK S ,  KANE-MAGUIRE KIM A ,  ZHANG XIAOMING ,  SCARBOROUGH ROBERT M

IPC: C07D401/02 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/506 ,  C07D217/24 ,  C07D401/04 ,  C07D409/12

Abstract: Isoquinolinone compounds are provided that are useful for the inhibition of ADP-platelet aggregation, particularly in the treatment of thrombosis and thrombosis related conditions or disorders.