公开(公告)号：DE60228081D1

公开(公告)日：2008-09-18

申请号：DE60228081

申请日：2002-06-19

Applicant: POSTECH FOUNDATION

Inventor： KIM BYEANG ,  KIM SU JEONG

IPC: C07H19/06 ,  C07H19/073 ,  C07F7/18 ,  C07H21/00

Abstract: The present invention relates to calix[4]arene-nucleoside hybrids containing calix[4]arene moieties and calix[4]arene-oligonucleotide hybrids as a DNA hairpin structure mimics synthesized by using the calix[4]arene-nucleoside as a key building block. Calix[4]arene-nucleoside and calix[4]arene-oligonucleotide hybrids of the present invention can effectively recognize DNA or RNA through triplex formation by bonding between calix[4]arene containing cavity and biologically active substance.