-
1.发明申请GRADIENT STRUCTURES INTERFACING MICROFLUIDICS AND NANOFLUIDICS, METHODS FOR FABRICATION AND USES THEREOF 审中-公开接触微流控和纳米级的梯度结构，其制造方法及其用途
公开(公告)号：WO2003106693A2
公开(公告)日：2003-12-24
申请号：PCT/US2003/011721
申请日：2003-04-16
Applicant: PRINCETON UNIVERSITY
Inventor： CAO, Han , TEGENFELDT, Jonas , CHOU, Stephen, Y.
IPC: C12Q
CPC classification number: G01N21/6486 , B01L3/502707 , B01L3/502715 , B01L3/502746 , B01L3/502761 , B01L2200/027 , B01L2200/0663 , B01L2200/12 , B01L2300/0654 , B01L2300/0896 , B01L2400/0415 , B01L2400/086 , B81B2201/058 , B81C1/00119 , B81C2201/0157 , B81C2201/0159 , B82Y30/00 , G01N33/48721 , G03F7/2008 , Y10T436/143333
Abstract: The present invention relates to a device for interfacing nanofluidic and microfluidic components suitable for use in performing high throughput macromolecular analysis. Diffraction gradient lithography (DGL) is used to form a gradient interface between a microfluidic area and a nanofluidic area. The gradient interface area reduces the local entropic barrier to anochannels formed in the nanofluidic area. In one embodiment, the gradient interface area is formed of lateral spatial gradient structures for narrowing the cross section of a value from the micron to the nanometer length scale. In another embodiment, the gradient interface area is formed of a vertical sloped gradient structure. Additionally, the gradient structure can provide both a lateral and vertical gradient.
Abstract translation: 本发明涉及适用于进行高通量大分子分析的纳米流体和微流体组分的界面装置。 衍射梯度光刻（DGL）用于在微流体区域和纳流体区域之间形成梯度界面。 梯度界面面积减小了在纳米流体区域中形成的各向异性的局部熵屏障。 在一个实施例中，梯度界面区域由横向空间梯度结构形成，用于使从微米到纳米长度尺度的值的横截面变窄。 在另一个实施例中，梯度界面区域由垂直倾斜梯度结构形成。 此外，梯度结构可以提供横向和垂直梯度。
-
2.发明申请
公开(公告)号：WO2003106693A3
公开(公告)日：2003-12-24
申请号：PCT/US2003/011721
申请日：2003-04-16
Applicant: PRINCETON UNIVERSITY
Inventor： CAO, Han , TEGENFELDT, Jonas , CHOU, Stephen, Y.
IPC: C12M1/34
Abstract: The present invention relates to a device for interfacing nanofluidic and microfluidic components suitable for use in performing high throughput macromolecular analysis. Diffraction gradient lithography (DGL) is used to form a gradient interface between a microfluidic area and a nanofluidic area. The gradient interface area reduces the local entropic barrier to anochannels formed in the nanofluidic area. In one embodiment, the gradient interface area is formed of lateral spatial gradient structures for narrowing the cross section of a value from the micron to the nanometer length scale. In another embodiment, the gradient interface area is formed of a vertical sloped gradient structure. Additionally, the gradient structure can provide both a lateral and vertical gradient.
-
公开(公告)号：EP1572860B1
公开(公告)日：2018-12-05
申请号：EP03751748.9
申请日：2003-04-16
Applicant: PRINCETON UNIVERSITY
Inventor： CAO, Han , TEGENFELDT, Jonas , CHOU, Stephen, Y.
CPC classification number: G01N21/6486 , B01L3/502707 , B01L3/502715 , B01L3/502746 , B01L3/502761 , B01L2200/027 , B01L2200/0663 , B01L2200/12 , B01L2300/0654 , B01L2300/0896 , B01L2400/0415 , B01L2400/086 , B81B2201/058 , B81C1/00119 , B81C2201/0157 , B81C2201/0159 , B82Y30/00 , G01N33/48721 , G03F7/2008 , Y10T436/143333
Abstract: The present invention relates to a device for interfacing nanofluidic and microfluidic components suitable for use in performing high throughput macromolecular analysis. Diffraction gradient lithography (DGL) is used to form a gradient interface between a microfluidic area and a nanofluidic area. The gradient interface area reduces the local entropic barrier to anochannels formed in the nanofluidic area. In one embodiment, the gradient interface area is formed of lateral spatial gradient structures for narrowing the cross section of a value from the micron to the nanometer length scale. In another embodiment, the gradient interface area is formed of a vertical sloped gradient structure. Additionally, the gradient structure can provide both a lateral and vertical gradient.
-
4.发明公开GRADIENT STRUCTURES INTERFACING MICROFLUIDICS AND NANOFLUIDICS, METHODS FOR FABRICATION AND USES THEREOF 有权梯度结构作为边界微流体与纳米流体，制造方法和应用
公开(公告)号：EP1572860A2
公开(公告)日：2005-09-14
申请号：EP03751748.9
申请日：2003-04-16
Applicant: PRINCETON UNIVERSITY
Inventor： CAO, Han , TEGENFELDT, Jonas , CHOU, Stephen, Y.
IPC: C12M1/34
CPC classification number: G01N21/6486 , B01L3/502707 , B01L3/502715 , B01L3/502746 , B01L3/502761 , B01L2200/027 , B01L2200/0663 , B01L2200/12 , B01L2300/0654 , B01L2300/0896 , B01L2400/0415 , B01L2400/086 , B81B2201/058 , B81C1/00119 , B81C2201/0157 , B81C2201/0159 , B82Y30/00 , G01N33/48721 , G03F7/2008 , Y10T436/143333
Abstract: The present invention relates to a device for interfacing nanofluidic and microfluidic components suitable for use in performing high throughput macromolecular analysis. Diffraction gradient lithography (DGL) is used to form a gradient interface between a microfluidic area and a nanofluidic area. The gradient interface area reduces the local entropic barrier to anochannels formed in the nanofluidic area. In one embodiment, the gradient interface area is formed of lateral spatial gradient structures for narrowing the cross section of a value from the micron to the nanometer length scale. In another embodiment, the gradient interface area is formed of a vertical sloped gradient structure. Additionally, the gradient structure can provide both a lateral and vertical gradient.
-
-
-
Search Results
4
records
(took 0.019 seconds)
