-
公开(公告)号：NZ623056A
公开(公告)日：2016-03-31
申请号：NZ62305612
申请日：2012-08-29
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , CHEN GUANGMING , GINZBURG OLYA , HUANG SONG , NARASIMHAN JANA , PEDDI SRINIVASA , SMITH SEAN WESLEY , WOLL MATTHEW G , ZHANG NANJING , ZHANG XIAOYAN , TURPOFF ANTHONY ALLAN
IPC: A61K31/473 , A61K31/435 , A61K31/4353 , A61K31/436 , A61K31/437 , A61K31/438 , A61K31/496 , A61K31/5377 , A61K31/55 , A61P31/04 , C07D221/10 , C07D221/14 , C07D221/16 , C07D401/04 , C07D471/04 , C07D471/14 , C07D491/044 , C07D491/048 , C07D491/052 , C07D491/14 , C07D495/04 , C07D519/00
Abstract: Provided are polycyclic quinolone derivative compounds of general formula (I), (II) or (III), wherein the variables are as defined in the specification. Examples of the compounds include 8-(dimethylamino)-2-oxo-1,2,5,6-tetrahydrobenzo[h]quinoline-3-carboxylic acid and 4-hydroxy-2-oxo-9-(pyrrolidin-1-yl)-1,2,5,6-tetrahydrobenzo[2,3]thiepino[4,5-b]pyridine-3-carboxylic acid. The compounds have antibacterial activity.
-
公开(公告)号：CL2014000469A1
公开(公告)日：2014-11-14
申请号：CL2014000469
申请日：2014-02-26
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , BAIRD JOHN DAVID , GINZBURG OLYA , NARASIMHAN JANA , PEDDI SRINIVASA , QI HONGYAN , YANG TIANLE , ZHANG XIAOYAN , CHEN GUANGMING , SMITH SEAN WESLEY , WOLL MATTHEW G , ZHANG NAJING
IPC: A01N43/40 , A61K31/4412 , A61K31/4427 , A61P31/04 , C07D213/60
-
公开(公告)号：MX2014002299A
公开(公告)日：2014-07-22
申请号：MX2014002299
申请日：2012-08-29
Applicant: PTC THERAPEUTICS INC
Inventor： JOSYULA VARA PRASAD VENKATA NAGENDRA , TURPOFF ANTHONY ALLAN , ZHANG XIAOYAN , CHEN GUANGMING , ZHANG NANJING , BRANSTROM ARTHUR , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , NARASIMHAN JANA , SMITH SEAN WESLEY , PEDDI SRINIVASA , GINZBURG OLYA , ARNOLD MICHAEL ANDREW , WOLL MATTEW G , HUANG SONG
IPC: A61K31/473
Abstract: La presente descripción se refiere a compuestos y formas y composiciones farmacéuticas de los mismos y métodos para usar los mismos para tratar o mejorar las infecciones bacterianas causadas por patógenos Gram-negativos y Gram-positivos resistentes a múltiples fármacos y de tipo silvestre; la presente descripción además se refiere a un compuesto que tiene actividad hacia las bacterias MDR y de tipo silvestre; la presente descripción también se refiere a un compuesto que tiene actividad contra cepas Gram-negativas resistentes a quinolona (incluyendo cepas MDR) como también actividad antibacteriana a patógenos Gram-positivos resistentes a MDR (incluyendo cepas MRSA).
-
公开(公告)号：ZA201402248B
公开(公告)日：2016-06-29
申请号：ZA201402248
申请日：2014-03-26
Applicant: PTC THERAPEUTICS INC
Inventor： ZHANG XIAOYAN , ZHANG NANJING , YANG TIANLE , WOLL MATTHEW G , SMITH SEAN WESLEY , QI HONGYAN , PEDDI SRINIVASA , NARASIMHAN JANA , GINZBURG OLYA , CHEN GUANGMING , BAIRD JOHN DAVID , WANG JIASHI , KARP GARY , GERASYUTO ALEKSEY I , ARNOLD MICHAEL ANDREW , JOSYULA VARA PRASAD VENKATA NAGENDRA , BRANSTROM ARTHUR
Abstract: The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens.
-
公开(公告)号：NZ623063A
公开(公告)日：2016-04-29
申请号：NZ62306312
申请日：2012-08-29
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , KARP GARY , WANG JIASHI , CHEN GUANGMING , GINZBURG OLYA , NARASIMHAN JANA , PEDDI SRINIVASA , SMITH SEAN WESLEY , WOLL MATTHEW G , ZHANG NANJING , ZHANG XIAOYAN , BAIRD JOHN DAVID , QI HONGYAN , YANG TIANLE , GERASYUTO ALEKSEY I
IPC: A61K31/4412 , A61K31/437 , A61K31/4427 , A61K31/4439 , A61K31/4709 , A61K31/5377 , A61P31/04 , C07D401/04 , C07D401/14 , C07D405/14 , C07D413/04 , C07D471/04
Abstract: Provided are dihydropyridine derivative compounds of the general formula (I), wherein the variables are as defined in the specification. Examples of the compounds include 5-ethyl-6-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid and 5-ethyl-4-hydroxy-2-oxo-6-(1H-pyrrolo[2,3-b]pyridin-6-yl)-1,2-dihydropyridine-3-carboxylic acid. The compounds are antibacterial agents.
-
Patent Agency Ranking
公开(公告)号：CL2014000468A1
公开(公告)日：2014-10-17
申请号：CL2014000468
申请日：2014-02-26
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , ARASU TAMIL , BAIRD JOHN DAVID , DU WU , GINZBURG OLYA , GORSKE YI JIN KIM , NARASIMHAN JANA , PEDDI SRINIVASA , QI HONGYAN , SMITH SEAN WESLEY , TURPOFF ANTHONY ALLAN , WILDE RICHARD GERALD , YANG TIANLE , ZHANG NANJING , ZHANG XIAOYAN
IPC: C07D211/42 , A01N43/40 , A61K31/44 , A61P31/04
-
公开(公告)号：AU2012301953C1
公开(公告)日：2016-11-03
申请号：AU2012301953
申请日：2012-08-29
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , BAIRD JOHN DAVID , CHEN GUANGMING , GINZBURG OLYA , NARASIMHAN JANA , PEDDI SRINIVASA , QI HONGYAN , SMITH SEAN WESLEY , WOLL MATTHEW G , YANG TIANLE , ZHANG NANJING , ZHANG XIAOYAN
IPC: A01N43/40
Abstract: The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens.
-
公开(公告)号：AU2012302022A8
公开(公告)日：2014-03-20
申请号：AU2012302022
申请日：2012-08-29
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , ARASU TAMIL , BAIRD JOHN DAVID , DU WU , GINZBURG OLYA , GORSKE YI JIN KIM , NARASIMHAN JANA , PEDDI SRINVASA , QI HONGYAN , SMITH SEAN WESLEY , TURPOFF ANTHONY ALLAN , WILDE RICHARD GERALD , YANG TIANLE , ZHANG NANJING , ZHANG XIAOYAN
Abstract: The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens.
-
公开(公告)号：CA2846663A1
公开(公告)日：2013-03-07
申请号：CA2846663
申请日：2012-08-29
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , QI HONGYAN , PEDDI SRINIVASA , WOLL MATTHEW G , SMITH SEAN WESLEY , CHEN GUANGMING , YANG TIANLE , ZHANG NANJING , GINZBURG OLYA , NARASIMHAN JANA , ZHANG XIAOYAN , BAIRD JOHN DAVID
IPC: A01N43/40
Abstract: The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens.
-
公开(公告)号：CA2846659A1
公开(公告)日：2013-03-07
申请号：CA2846659
申请日：2012-08-29
Applicant: PTC THERAPEUTICS INC
Inventor： BRANSTROM ARTHUR , JOSYULA VARA PRASAD VENKATA NAGENDRA , ARNOLD MICHAEL ANDREW , GERASYUTO ALEKSEY I , KARP GARY , WANG JIASHI , BAIRD JOHN DAVID , DU WU , ZHANG XIAOYAN , PEDDI SRINIVASA , TURPOFF ANTHONY ALLAN , WILDE RICHARD GERALD , QI HONGYAN , GINZBURG OLYA , GORSKE YI JIN KIM , ZHANG NANJING , NARASIMHAN JANA , SMITH SEAN WESLEY , ARASU TAMIL , YANG TIANLE
Abstract: The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens.
-
-
-
-
-
-
-
-
-
Search Results
25
records
(took 0.025 seconds)
