公开(公告)号：DE69131319T2

公开(公告)日：1999-12-16

申请号：DE69131319

申请日：1991-04-17

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO F ,  GIULIANI MARZIA M

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  A61K39/118 ,  G01N33/569

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：DE69131319D1

公开(公告)日：1999-07-15

申请号：DE69131319

申请日：1991-04-17

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO F ,  GIULIANI MARZIA M

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  A61K39/118 ,  G01N33/569

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：AT181104T

公开(公告)日：1999-06-15

申请号：AT91106110

申请日：1991-04-17

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO F ,  GIULIANI MARZIA M

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  A61K39/118 ,  G01N33/569

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：DK0499681T3

公开(公告)日：1999-11-15

申请号：DK91106110

申请日：1991-04-17

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO F ,  GIULIANI MARZIA M

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  A61K39/118 ,  C07K15/00 ,  G01N33/569

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：GR3030447T3

公开(公告)日：1999-09-30

申请号：GR990401491

申请日：1999-06-10

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO F ,  GIULIANI MARZIA M

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  A61K39/118 ,  G01N33/569

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：IT1224253B

公开(公告)日：1990-09-26

申请号：IT2013288

申请日：1988-04-08

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  RICCI STEFANO ,  GARUTI GIANCARLO ,  COSCO EGIDIO

IPC: C07K14/295 ,  C12Q1/68 ,  C12Q1/6841 ,  C12Q1/689 ,  C12Q

公开(公告)号：IT1244706B

公开(公告)日：1994-08-08

申请号：ITMI910314

申请日：1991-02-07

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO FELICE ,  GIULIANI MARZIA

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  C12K ,  A61K

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：ITMI910314D0

公开(公告)日：1991-02-07

申请号：ITMI910314

申请日：1991-02-07

Applicant: SCLAVO SPA ,  SCAVO

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO FELICE ,  GIULIANI MARZIA

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  C12K ,  A61K

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：ES2136062T3

公开(公告)日：1999-11-16

申请号：ES91106110

申请日：1991-04-17

Applicant: SCLAVO SPA

Inventor： RATTI GIULIO ,  COMANDUCCI MAURIZIO ,  TECCE MARIO F ,  GIULIANI MARZIA M

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74 ,  A61K39/118 ,  G01N33/569

Abstract: A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.

公开(公告)号：ITMI910314A1

公开(公告)日：1992-08-08

申请号：ITMI910314

申请日：1991-02-07

Applicant: SCLAVO SPA

Inventor： COMANDUCCI MAURIZIO ,  GIULIANI MARZIA ,  RATTI GIULIO ,  TECCE MARIO FELICE

IPC: A61K20060101 ,  A61K38/00 ,  A61K39/00 ,  C07K14/295 ,  C07K16/12 ,  C12N15/30 ,  C12N15/74