公开(公告)号：IT1230712B

公开(公告)日：1991-10-29

申请号：IT1940889

申请日：1989-02-10

Applicant: SCLAVO SPA

Inventor： NENCIONI LUCIANO ,  PILERI PIERO ,  PEPPOLONI SAMUELE ,  SILVESTRI SERGIO

IPC: A61K39/00 ,  A61P37/00 ,  C07K5/02 ,  C07K16/00 ,  C12K

公开(公告)号：CA1338318C

公开(公告)日：1996-05-07

申请号：CA601098

申请日：1989-05-30

Applicant: SCLAVO SPA

Inventor： NENCIONI LUCIANO ,  PILERI PIERO ,  PEPPOLONI SAMUELE ,  SILVESTRI SERGIO

IPC: A61K39/00 ,  A61P37/00 ,  C07K5/02 ,  C07K16/00 ,  A61K39/39

Abstract: The invention is concerned with the use of a compound analogous to tuftsin, having the formula (I) (I) or of a pharmaceutically acceptable base-addition or acid-addition salt thereof, as an adjuvant in order to potentiate, in a living organism, the antibody response against either natural or synthetic antigens, as well as with the novel compositions for vaccines which comprise one or more of said antigens together with an adjuvating amount of the compound of formula (I) or of one of its addition salts.

公开(公告)号：DE68917907T2

公开(公告)日：1995-01-05

申请号：DE68917907

申请日：1989-05-30

Applicant: SCLAVO SPA

Inventor： NENCIONI LUCIANO ,  PILERI PIERO ,  PEPPOLONI SAMUELE ,  SILVESTRI SERGIO

IPC: A61K39/00 ,  A61P37/00 ,  C07K5/02 ,  C07K16/00 ,  A61K39/39

公开(公告)号：AT110739T

公开(公告)日：1994-09-15

申请号：AT89201371

申请日：1989-05-30

Applicant: SCLAVO SPA

Inventor： NENCIONI LUCIANO ,  PILERI PIERO ,  PEPPOLONI SAMUELE ,  SILVESTRI SERGIO

IPC: A61K39/00 ,  A61P37/00 ,  C07K5/02 ,  C07K16/00 ,  A61K39/39

公开(公告)号：IT8922791D0

公开(公告)日：1989-12-21

申请号：IT2279189

申请日：1989-12-21

Applicant: SCLAVO SPA

Inventor： BECHERUCCI CRISTINA ,  PERRETTI MAURO ,  SILVESTRI SERGIO ,  PARENTE LUCA

IPC: A61K38/07 ,  A61K38/00 ,  A61P29/00 ,  C07K5/10 ,  A61K

Abstract: The use of natural tuftsin (I) and retro-inverted tuftsin (II) or a pharmaceutically acceptable salt of basic or acid addition thereof as anti-inflammatory agents for the treatment of illnesses of inflammatory pathogenesis is described, together with pharmaceutical compositions comprising a therapeutically effective quantity of compound (I) or (II) or of their salts of addition.

公开(公告)号：DE68917907D1

公开(公告)日：1994-10-06

申请号：DE68917907

申请日：1989-05-30

Applicant: SCLAVO SPA

Inventor： NENCIONI LUCIANO ,  PILERI PIERO ,  PEPPOLONI SAMUELE ,  SILVESTRI SERGIO

IPC: A61K39/00 ,  A61P37/00 ,  C07K5/02 ,  C07K16/00 ,  A61K39/39

公开(公告)号：IT1239477B

公开(公告)日：1993-11-02

申请号：IT2279189

申请日：1989-12-21

Applicant: SCLAVO SPA

Inventor： BECHERUCCI CRISTINA ,  PERRETTI MAURO ,  SILVESTRI SERGIO ,  PARENTE LUCA

IPC: A61K38/07 ,  A61K38/00 ,  A61P29/00 ,  C07K5/10 ,  A61K

Abstract: The use of natural tuftsin (I) and retro-inverted tuftsin (II) or a pharmaceutically acceptable salt of basic or acid addition thereof as anti-inflammatory agents for the treatment of illnesses of inflammatory pathogenesis is described, together with pharmaceutical compositions comprising a therapeutically effective quantity of compound (I) or (II) or of their salts of addition.

公开(公告)号：IT1245867B

公开(公告)日：1994-10-25

申请号：ITRM910385

申请日：1991-06-03

Applicant: CONSIGLIO NAZIONALE RICERCHE ,  SCLAVO SPA

Inventor： BENATTI UMBERTO ,  DE FLORA ANTONIO ,  POLVANI CAROLINA ,  NENCIONI LUCIANO ,  SILVESTRI SERGIO

IPC: A61K9/50 ,  A61K39/05 ,  A61K39/08 ,  A61K39/10 ,  A61K39/385 ,  A61K

公开(公告)号：IT8919408D0

公开(公告)日：1989-02-10

申请号：IT1940889

申请日：1989-02-10

Applicant: SCLAVO SPA

Inventor： NENCIONI LUCIANO ,  PIERI PIERO ,  PEPPOLONI SAMUELE ,  SILVESTRI SERGIO

IPC: A61K39/00 ,  A61P37/00 ,  C07K5/02 ,  C07K16/00

公开(公告)号：ES2058473T3

公开(公告)日：1994-11-01

申请号：ES89201371

申请日：1989-05-30

Applicant: SCLAVO SPA

Inventor： NENCIONI LUCIANO ,  PILERI PIERO ,  PEPPOLONI SAMUELE ,  SILVESTRI SERGIO

IPC: A61K39/00 ,  A61P37/00 ,  C07K5/02 ,  C07K16/00 ,  A61K39/39