公开(公告)号：AT205602T

公开(公告)日：2001-09-15

申请号：AT91902046

申请日：1990-12-14

Applicant: SENSOR TECHNOLOGIES INC

Inventor： CHICK WILLIAM L ,  WOLF DAVID E ,  CARDULLO RICHARD A

IPC: G01N33/53 ,  A61K49/00 ,  G01N33/542 ,  G01N33/58 ,  G01N33/66 ,  G01N33/68 ,  G01N33/566

Abstract: A method for quantifying glucose concentration in blood, body fluids, and other samples within, below and above the normal physiological range, which relies on non-radiative fluorescence resonance energy transfer, as well as devices useful in quantifying blood glucose concentration using the present method.

公开(公告)号：EP0649476A4

公开(公告)日：1997-05-07

申请号：EP93916805

申请日：1993-06-28

Applicant: SENSOR TECHNOLOGIES INC

Inventor： CHICK WILLIAM L ,  WOLF DAVID E ,  CARDULLO RICHARD A

IPC: C12Q1/68 ,  G01N33/52 ,  G01N33/58

CPC classification number: C12Q1/6818 ,  C12Q1/6825 ,  G01N33/52 ,  G01N33/582 ,  C12Q2565/107 ,  C12Q2563/107

Abstract: An in vivo method and apparatus for detecting an analyte in an individual. A sensor that includes a fluorescence reagent is placed in communication with the body fluids of the individual suspected of containing the analyte in such a way that once in place said sensor does not exit the skin of the individual. The sensor is configured to retain the fluorescence reagent while allowing analyte to diffuse into and out of said sensor. The sensor is illuminated transdermally, and the fluorescence from the fluorescence reagent associated with the presence of the analyte is measured.