公开(公告)号：DE69839149T2

公开(公告)日：2009-02-26

申请号：DE69839149

申请日：1998-06-04

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: G01N33/542 ,  A61B5/00 ,  A61K49/00 ,  G01N33/53 ,  G01N33/66 ,  G01N33/68

公开(公告)号：DE69839149D1

公开(公告)日：2008-04-03

申请号：DE69839149

申请日：1998-06-04

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: G01N33/542 ,  A61B5/00 ,  A61K49/00 ,  G01N33/53 ,  G01N33/66 ,  G01N33/68

公开(公告)号：AT205602T

公开(公告)日：2001-09-15

申请号：AT91902046

申请日：1990-12-14

Applicant: SENSOR TECHNOLOGIES INC

Inventor： CHICK WILLIAM L ,  WOLF DAVID E ,  CARDULLO RICHARD A

IPC: G01N33/53 ,  A61K49/00 ,  G01N33/542 ,  G01N33/58 ,  G01N33/66 ,  G01N33/68 ,  G01N33/566

Abstract: A method for quantifying glucose concentration in blood, body fluids, and other samples within, below and above the normal physiological range, which relies on non-radiative fluorescence resonance energy transfer, as well as devices useful in quantifying blood glucose concentration using the present method.

公开(公告)号：AU5918799A

公开(公告)日：2000-04-03

申请号：AU5918799

申请日：1999-09-10

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: A61K49/00 ,  G01N33/53 ,  G01N33/66 ,  A61B5/00 ,  A61K38/39 ,  C07K14/78 ,  G01N33/542 ,  G01N33/566

公开(公告)号：AU1623300A

公开(公告)日：2000-06-05

申请号：AU1623300

申请日：1999-11-12

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: A61K9/00 ,  A61K9/50 ,  A61K49/00 ,  B01J13/02 ,  B32B3/00

Abstract: An article is disclosed that includes a core and a selectively permeable coating enclosing the core. The coating includes a monodisperse polymer.

公开(公告)号：AU8058798A

公开(公告)日：1998-12-21

申请号：AU8058798

申请日：1998-06-04

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: A61B5/00 ,  G01N33/53 ,  G01N33/66 ,  G01N33/68 ,  G01N33/566 ,  A61K49/00 ,  G01N33/542

公开(公告)号：WO0016099A9

公开(公告)日：2000-08-10

申请号：PCT/US9920853

申请日：1999-09-10

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: A61K49/00 ,  G01N33/53 ,  G01N33/66 ,  A61B5/00 ,  A61K38/39 ,  C07K14/78 ,  G01N33/542 ,  G01N33/566

CPC classification number: A61K49/0056 ,  A61K49/0021 ,  A61K49/0041 ,  A61K49/0043 ,  G01N33/5308 ,  G01N33/66 ,  Y02P20/582

Abstract: The invention is based on the discovery of reduced valency carbohydrate binding ligands (CBLs) that can be used to detect or quantitate (i.e., evaluate) carbohydrates in a sample. CBLs can be used with fluorescence resonance energy transfer (FRET) to evaluate free carbohydrates or those within a carbohydrate containing compound.

Abstract translation: 本发明基于可用于检测或定量（即评估）样品中碳水化合物的降低的价态碳水化合物结合配体（CBL）的发现。 CBL可以与荧光共振能量转移（FRET）一起使用，以评估游离碳水化合物或含碳水化合物的碳水化合物。

公开(公告)号：EP0986757A4

公开(公告)日：2004-08-25

申请号：EP98928894

申请日：1998-06-04

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: A61B5/00 ,  G01N33/53 ,  G01N33/66 ,  G01N33/68 ,  G01N33/542 ,  A61K49/00

CPC classification number: G01N33/6842 ,  A61B5/14532 ,  A61B5/1455 ,  G01N33/5308 ,  G01N33/66 ,  G01N33/68 ,  G01N2400/00 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/815 ,  Y10S436/827 ,  Y10T436/104998 ,  Y10T436/144444

Abstract: A method of evaluating a carbohydrate in a sample. The method includes providing a low valency carbohydrate binding ligand, providing a glycoconjugate which includes a label, and a carbohydrate moiety, contacting the low valency carbohydrate binding ligand and the glycoconjugate with the sample, determining the extent of binding of the low valency carbohydrate binding ligand with the glycoconjugate, the binding of the low valency carbohydrate binding ligand with the glycoconjugate being correlated with the amount of carbohydrate in the sample.

公开(公告)号：EP0649476A4

公开(公告)日：1997-05-07

申请号：EP93916805

申请日：1993-06-28

Applicant: SENSOR TECHNOLOGIES INC

Inventor： CHICK WILLIAM L ,  WOLF DAVID E ,  CARDULLO RICHARD A

IPC: C12Q1/68 ,  G01N33/52 ,  G01N33/58

CPC classification number: C12Q1/6818 ,  C12Q1/6825 ,  G01N33/52 ,  G01N33/582 ,  C12Q2565/107 ,  C12Q2563/107

Abstract: An in vivo method and apparatus for detecting an analyte in an individual. A sensor that includes a fluorescence reagent is placed in communication with the body fluids of the individual suspected of containing the analyte in such a way that once in place said sensor does not exit the skin of the individual. The sensor is configured to retain the fluorescence reagent while allowing analyte to diffuse into and out of said sensor. The sensor is illuminated transdermally, and the fluorescence from the fluorescence reagent associated with the presence of the analyte is measured.

公开(公告)号：EP1546675A4

公开(公告)日：2008-03-26

申请号：EP03767274

申请日：2003-08-01

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E ,  BULSECO DYLAN A

IPC: G01N33/58 ,  C12M1/00 ,  C12M1/34 ,  C12N15/09 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/68 ,  C12Q1/70 ,  G01J3/44 ,  G01J3/457 ,  G01N21/64 ,  G01N21/78

CPC classification number: G01N21/6428 ,  G01J3/4406 ,  G01J3/457 ,  G01N21/645 ,  G01N33/582 ,  G01N2021/6417 ,  G01N2021/6482 ,  G01N2021/6484

Abstract: The invention features a method of assaying for the interaction of a probe and an unknown target, said method including a) exciting a sample with radiation, the sample including at least one unknown target, at least one probe, and at least one fluorescent tag, b) measuring the fluorescence from a subvolume of the sample, and c) analyzing the fluctuations of the fluorescence.