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公开(公告)号:AU4378400A
公开(公告)日:2001-01-04
申请号:AU4378400
申请日:2000-06-30
Applicant: SERVIER LAB
Inventor: NANTEUIL GUILLAUME DE , BENOIST ALAIN , BONNET JACQUELINE , SBATINI MASSIMO , ATASSI GHANEM , PIERRE ALAIN
IPC: C07D307/77 , A61K31/4355 , A61K31/4406 , A61K31/4409 , A61K31/4453 , A61K31/506 , A61K31/5377 , A61P9/10 , A61P19/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D491/04 , C07D491/048
Abstract: N-Arylsulfonyl tetrahydrofuropyridine carboxylic acid derivatives (I), their isomers and acid and base addition salts, their preparation and compositions containing them. N-Arylsulfonyl tetrahydrofuropyridine carboxylic acid derivatives of formula (I), their isomers and acid and base addition salts, their preparation and compositions containing them: R1 = H, halogen, 1-6C alkyl or alkoxy; R2 = OH, 1-6C alkoxy, or NHOH; Ar1 = phenylene or biphenylene; X = O, S, NR, -OC- or a bond; R = H, or 1-6C alkyl; n = 0-6; Ar2 = phenyl substituted by heteroaryl, biphenyl substituted by heteroaryl, pyridinyl substituted by heteroaryl, or a heterocycle
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公开(公告)号:AU770168B2
公开(公告)日:2004-02-12
申请号:AU4378400
申请日:2000-06-30
Applicant: SERVIER LAB
Inventor: NANTEUIL GUILLAUME DE , BENOIST ALAIN , BONNET JACQUELINE , SBATINI MASSIMO , ATASSI GHANEM , PIERRE ALAIN
IPC: C07D307/77 , A61K31/4355 , A61K31/4406 , A61K31/4409 , A61K31/4453 , A61K31/506 , A61K31/5377 , A61P9/10 , A61P19/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D491/04 , C07D491/048
Abstract: N-Arylsulfonyl tetrahydrofuropyridine carboxylic acid derivatives (I), their isomers and acid and base addition salts, their preparation and compositions containing them. N-Arylsulfonyl tetrahydrofuropyridine carboxylic acid derivatives of formula (I), their isomers and acid and base addition salts, their preparation and compositions containing them: R1 = H, halogen, 1-6C alkyl or alkoxy; R2 = OH, 1-6C alkoxy, or NHOH; Ar1 = phenylene or biphenylene; X = O, S, NR, -OC- or a bond; R = H, or 1-6C alkyl; n = 0-6; Ar2 = phenyl substituted by heteroaryl, biphenyl substituted by heteroaryl, pyridinyl substituted by heteroaryl, or a heterocycle
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