公开(公告)号：US12121897B2

公开(公告)日：2024-10-22

申请号：US16769103

申请日：2018-12-21

Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY

Inventor： Hairong Zheng ,  Fei Li ,  Feiyan Cai ,  Long Meng ,  Yang Xiao ,  Fei Yan

IPC: B01L3/00 ,  B06B1/06 ,  B82Y35/00

CPC classification number: B01L3/502753 ,  B06B1/06 ,  B01L2400/0409 ,  B01L2400/0436 ,  B82Y35/00

Abstract: A microfluidic system, including: a container, an ultrasound transmitter assembly, and a phononic crystal plate. The container is configured to accommodate a solution containing microparticles. The ultrasound transmitter assembly is configured to transmit ultrasonic waves to the phononic crystal plate, where the ultrasonic waves have a frequency which is the same as a resonance frequency of the phononic crystal plate. The phononic crystal plate is placed in the solution, and configured to generate a local acoustic field on a surface of the phononic crystal plate under excitation of the ultrasonic waves, and induce an acoustic microstreaming vortex to generate an acoustic streaming shear stress on the microparticles. The phononic crystal plate defines therein cavities, the respective cavities are arranged periodically in the phononic crystal plate, and all the respective cavities are filled with gas.

公开(公告)号：US10780437B2

公开(公告)日：2020-09-22

申请号：US15742491

申请日：2015-10-10

Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY, CHINESE ACADEMY OF SCIENCES

Inventor： Hairong Zheng ,  Fei Li ,  Feiyan Cai ,  Long Meng ,  Chen Wang ,  Chengxiang Zhang ,  Weibao Qiu ,  Yongchuan Li ,  Fei Yan ,  Lili Niu ,  Liufeng Geng ,  Chaowei Xu

IPC: B01L3/00 ,  C12N13/00 ,  G01N15/10 ,  G01N15/00

Abstract: Disclosed is a microfluidic system based on an artificially structured acoustic field, comprising a microcavity used to accommodate a solution containing particles and a ultrasonic emission device used to emit ultrasound, and further comprising a phononic crystal plate placed in the microcavity. The phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. Also disclosed is a method of controlling microfluid particles based on an artificially structured acoustic field. In the particular embodiments, since a microcavity, an ultrasonic emission device and a phononic crystal plate are comprised, the ultrasonic emission device is used to emit ultrasound, and the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles.