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公开(公告)号：DE69209698T2
公开(公告)日：1996-08-08
申请号：DE69209698
申请日：1992-02-18
Applicant: SHIMADZU CORP
Inventor： TAMURA TOMOMI , EDA HIDEO
Abstract: Disclosed herein is an optical organism measuring apparatus in which cables provided on both light transmission and receiving sides are sufficiently reduced in diameter and provided with flexibility for attaining handleability while light can be transmitted and received in high efficiency so that information can be obtained from a deep portion in an organism. Semiconductor lasers (2-1, 2-2, 2-3) are coupled with incident ends of a plurality of single core optical fibers which are contained in a flexible probe (12), so that laser light guided by the single core optical fibers is applied to an organism (8) from a forward end portion of the probe (12). A light receiving probe (18) is provided on its forward end with a silicon photodiode (14), which is attached in close contact to the organism (8) to receive light transmitted through or reflected by the organism (8). This silicon photodiode (14) is integrated with a preamplifier (16). A cable for transmitting a detection signal which is amplified by the preamplifier (16) is formed by a flexible shielding wire.
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公开(公告)号：DE69209698D1
公开(公告)日：1996-05-15
申请号：DE69209698
申请日：1992-02-18
Applicant: SHIMADZU CORP
Inventor： TAMURA TOMOMI , EDA HIDEO
Abstract: Disclosed herein is an optical organism measuring apparatus in which cables provided on both light transmission and receiving sides are sufficiently reduced in diameter and provided with flexibility for attaining handleability while light can be transmitted and received in high efficiency so that information can be obtained from a deep portion in an organism. Semiconductor lasers (2-1, 2-2, 2-3) are coupled with incident ends of a plurality of single core optical fibers which are contained in a flexible probe (12), so that laser light guided by the single core optical fibers is applied to an organism (8) from a forward end portion of the probe (12). A light receiving probe (18) is provided on its forward end with a silicon photodiode (14), which is attached in close contact to the organism (8) to receive light transmitted through or reflected by the organism (8). This silicon photodiode (14) is integrated with a preamplifier (16). A cable for transmitting a detection signal which is amplified by the preamplifier (16) is formed by a flexible shielding wire.
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公开(公告)号：JPH10179558A
公开(公告)日：1998-07-07
申请号：JP27819997
申请日：1997-09-25
Applicant: SHIMADZU CORP
Inventor： KUMAZAWA YOSHIHIKO , EDA HIDEO , TSUNASAWA YOSHIO , ODA ICHIRO , KUMAGAI HIROAKI
Abstract: PROBLEM TO BE SOLVED: To obtain data on the concentration of an absorbent contained in a subject without measuring the intensity of incident light. SOLUTION: Fine laser beams are irradiated from a laser beam irradiation device 10 to a subject 71, and the beams transmitted through the subject 71 and outgoing therefrom are made incident on a solid image pickup element 12. At the same time, the beams are scanned, and picture element data along an optical axis obtainable from a solid image pickup element 12 as well as picture element group data around the optical axis are stored in an image processing memory 17 via an image collection memory 14. Also, an absorbance difference is obtained from the two types of data with a CPU 18, thereby calculating data on the concentration of an absorbent contained in the subject 71.
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公开(公告)号：JPH0838480A
公开(公告)日：1996-02-13
申请号：JP19739894
申请日：1994-07-30
Applicant: SHIMADZU CORP
Inventor： TSUNASAWA YOSHIO , NAKAMURA KAN , EDA HIDEO , ODA ICHIRO
Abstract: PURPOSE:To provide a living body measuring device by a photon counting method by counting the signal from a light detector for detecting the light from a testee, which is irradiated with high speed modulated light, by a counter connected to a plurality of time gate circuits operated in mutually different phases, respectively, through a discriminator. CONSTITUTION:The modulated light from a laser diode 22 is applied to a testee 2, and the diffuse-transmitted reflected light is detected by a photomultiplier 30. A high voltage power source 34 applies a high voltage to the photomultiplier 30 with a frequency according to the harmonic pulse signal from an oscillator 32, and the frequency of the harmonic pulse signal from the oscillator 32 is set slightly different from the frequency for driving the laser diode 22. The output signal of the photomultiplier 30 is inputted in parallel into n-pieces of time gate circuits 40-1 to 40-n, the gate signal from a gate signal generating circuit 42 formed on the basis of the reference pulse from the oscillator 20 is applied to a gate driving circuit 44, and the measured values of counters 46-1 to 46-n are taken into a CPU 50.
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公开(公告)号：JPH0588608B2
公开(公告)日：1993-12-22
申请号：JP19620989
申请日：1989-07-28
Applicant: SHIMADZU CORP
Inventor： EDA HIDEO
IPC: G01N21/31 , A61B5/145 , A61B5/1455 , A61B5/14
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Patent Agency Ranking
公开(公告)号：JPH04110756A
公开(公告)日：1992-04-13
申请号：JP23137690
申请日：1990-08-31
Applicant: SHIMADZU CORP
Inventor： TSUNASAWA YOSHIO , TAMURA TOMOMI , EDA HIDEO
Abstract: PURPOSE:To provide measurability for the absolute value of photo-absorptivity by performing auto zero processing of the photo-absorptivity including the auto gain setting to the standard of known photo-absorptivity in which the absorptivity is not zero, and using the absorptivity point-of-origin standard independent of patient. CONSTITUTION:Auto zero processing of photo-absorptivity including auto gain setting is conducted to the standard of known photo-absorptivity where the absorptivity is not zero, and thereupon the initial photo-absorptivity value of a vital body specimen is measured. Then a similar auto zero processing is made again, and change in the photo-absorptivity thereafter is measured. In the standard 1 of known photo- absorptivity where the absorptivity is not zero, a light sending part 4a of a absorption side light guide 4 is installed at an opening of a light input part 2, and there the light is projected over. This projected light 6 diffuses at the inner surface of the light input part 2. The photo-receiving part 10a of a reception side light guide 10 is installed at the outlet opening of the light output part 8, and the diffused light 12 by the output part 8 is put incident to this light guide 10. A junction 14 is provided between these light input and output parts 2, 8, and setting is made so that an appropriate reduction of light intensity is obtained.
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公开(公告)号：JPH0360646A
公开(公告)日：1991-03-15
申请号：JP19620989
申请日：1989-07-28
Applicant: SHIMADZU CORP
Inventor： EDA HIDEO
IPC: G01N21/31 , A61B5/145 , A61B5/1455
Abstract: PURPOSE:To enhance the measuring accuracy by using two wavelength in which the degrees of photo-absorbance vary oppositely according to change in the degree of blood saturation with oxygen and also using a wavelength with an invariable phot- absorbance. CONSTITUTION:Two wavelengths lambda1, lambda2 have the degrees of photo-absorbance varying oppositely according to the change in the degree of blood saturation with oxygen (for ex., 780nm and 830nm) while a third wavelength has a degree of photo-absorbance not varying (for ex., 805nm), and the light with wavelength lambda1 from an LED 6 is cast onto an ear 1, and a light receiving part 9 emits a voltage according to the intensity of this light. This voltage is A/D converted and stored in a RAM 17 by a control part 3. Then the wavelength lambda2 is emitted from an LED 7, and the result from sensing is stored in the RAM 17. Then the wavelength lambda3 is emitted from an LED 8, and the result from sensing is stored in the RAM 17. Then an air pressure adjusting device 14 is driven, and a cuff 10 is swollen, and the ear 1 is stopped by pressure at a certain pressure level, and measurement is conducted using the wavelengths lambda1, lambda2, lambda3. The degree of oxygen saturation is calculated using [degree of oxygen saturation]=A-B(I780-I830)/I805, where A, B are factor and I is amount of penetrative light, and the result is displayed on LCD 4.
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公开(公告)号：JPH1019766A
公开(公告)日：1998-01-23
申请号：JP17652596
申请日：1996-07-05
Applicant: SHIMADZU CORP
Inventor： TAKEUCHI SADAO , IWAMOTO SHINICHI , TSUNEISHI SHOICHI , EDA HIDEO
IPC: G01N21/27 , A61B5/145 , A61B5/1455 , A61B5/14
Abstract: PROBLEM TO BE SOLVED: To achieve a higher safety by reducing disturbance as caused by a laser light and an automatic restarting of the measurement of temporary lifting or deviation of a probe for measurement when the lifting or deviation occur in a measuring apparatus for a light scattering body. SOLUTION: This apparatus is provided with a light emitting section 21 for irradiating a specimen with light, a probe 20 for measurement integrated with photodetecting sections 22 and 23 to detect light, light control means 18 and 19 to control the irradiation of light and signal processing means 16, 17 and 11 to process detection signals obtained by the photodetecting sections. The incoming state of disturbed light is detected by the signal processing means to alter the irradiated condition of the light by a light control means according to the admission of disturbed light. This achieves a higher safety by reducing disturbance as caused by a laser light when the probe for measurement happens to lift or deviate and enables automatically restarting of the measurement of temporary lifting or deviation of the probe for measurement.
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公开(公告)号：JPH0843295A
公开(公告)日：1996-02-16
申请号：JP19745794
申请日：1994-07-29
Applicant: SHIMADZU CORP
Inventor： ODA ICHIRO , TSUNASAWA YOSHIO , EDA HIDEO
Abstract: PURPOSE:To optically measure a biological organism dealing with the light quantity over a wide range, to relatively shorten the measuring time, and to realize a small size and a low cost. CONSTITUTION:Pulses of light from a light source 22 are emitted toward a specimen 28 to be detected, and a diffused transmitted reflected light to be emitted from the position separated from a light emitting point is received by a photomultiplier 32. The photomultiplier 32 is driven by a gate signal synchronized with the irradiation light, and the signal is set to shorter than the interval T of the irradiation light pulse train, delayed, and the delay is sequentially varied. The signal of the photomultiplier 32 is integrated by an integrator 44 via a preamplifier 40, and fetched, and the integrated signal is sequentially changed between 0 to T to the light propagating waveform.
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公开(公告)号：JPH05300887A
公开(公告)日：1993-11-16
申请号：JP13611092
申请日：1992-04-27
Applicant: SHIMADZU CORP
Inventor： EDA HIDEO
IPC: A61B5/026
Abstract: PURPOSE:To convert the state of blood in a brain with a simple construction by a method wherein a belt wound on a head part is provided with a transmitting/receiving section. an output of a photodetector converted into digital from analog is compared with an initial value set to determine a difference. which is outputted to a post display device to display changes in the photodetector output. CONSTITUTION:Light emitting elements 4 such as LED and photodetectors 6 such as photodiode are mounted in a plurality of sets on a belt 2 wound on a head part 16 and an A/D conversion circuit 10 is provided to convert detection outputs of a lighting circuit 8 for lighting the light emitting elements 4 and the photodetectors 6 into digital values. A display control section 12 compares the outputs of the photodetectors with an initial value to determine a difference and the results are outputted to the display device 14, which 14 displays changes in the outputs of the photodetectors on a display screen according to an output from the display control section 12. The display of the difference is performed by color coding or the like. When the sets of the LEDs and the photodiodes are arranged at equal intervals as predetermined beforehand, initialization is accomplished simply by winding the head part with the belt 2.
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