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公开(公告)号：CZ20032496A3
公开(公告)日：2003-12-17
申请号：CZ20032496
申请日：2002-03-06
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： PATEL RAMESH , GOSWAMI ANIMESH , CHU LINDA N , NANDURI VENKATA B , GOLDBERG STEVEN L , JOHNSTON ROBERT M , DONOVAN MARY JO , MIRFAKHRAE K DAVID
Abstract: The present invention is directed to novel stereoselective processes for the preparation of (S)-1-arylethanols by the reduction of the corresponding keto group containing compounds by microorganisms. (S)-1-arylethanols are useful as intermediates in the synthesis of compounds that are inhibitors of gamma-secretase useful in the treatment of Alzheimer's disease.
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