公开(公告)号：WO1989012461A1

公开(公告)日：1989-12-28

申请号：PCT/US1989002404

申请日：1989-06-01

Applicant: ST. LOUIS UNIVERSITY

Inventor： ST. LOUIS UNIVERSITY ,  GREEN, Maurice ,  LOEWENSTEIN, Paul, M.

IPC: A61K39/12

CPC classification number: C07K14/005 ,  A61K38/00 ,  C12N2710/10322 ,  C12N2710/20022 ,  C12N2740/16322

Abstract: A method for preparing antagonists of viral transactivating proteins is disclosed. In one aspect the method involves the preparation of antagonists from active domains of the viral transactivating protein. Pharmaceutical compositions comprising the antagonists which compositions are useful in treating an individual suffering from viral infection are also disclosed.

Abstract translation: 公开了一种制备病毒反式激活蛋白质的拮抗剂的方法。 在一个方面，该方法涉及从病毒反式激活蛋白的活性结构域制备拮抗剂。 还公开了包含该组合物可用于治疗患有病毒感染的个体的拮抗剂的药物组合物。