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    A HIGH FLOW NASAL THERAPY SYSTEM
    1.
    发明申请
    A HIGH FLOW NASAL THERAPY SYSTEM 审中-公开
    高流量NASAL治疗系统

    公开(公告)号：WO2015155342A1

    公开(公告)日：2015-10-15

    申请号：PCT/EP2015/057866

    申请日：2015-04-10

    Applicant: STAMFORD DEVICES LIMITED

    Inventor： MACLOUGHLIN, Ronan ,  SMITH, Niall

    IPC: A61M11/00 ,  A61M15/00 ,  A61M16/00 ,  A61M16/06 ,  A61M16/10 ,  A61M16/14 ,  A61M16/16 ,  A61M16/08 ,  A61M16/20 ,  A61M15/08

    CPC classification number: A61M16/16 ,  A61M11/00 ,  A61M15/08 ,  A61M16/0666 ,  A61M16/0833 ,  A61M16/0866 ,  A61M16/0875 ,  A61M16/1095 ,  A61M16/14 ,  A61M16/202 ,  A61M2016/0018 ,  A61M2016/0027 ,  A61M2016/0033 ,  A61M2016/0036 ,  A61M2205/33 ,  A61M2205/3334

    Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.

    Abstract translation: 高流量鼻腔治疗系统（1）具有气体供应（2），雾化器（12）和鼻部接口（7）。 有两个分支（11,10）和与控制器连接的阀（6），分支包括用于输送气溶胶的第一分支（11）和用于输送非气雾化气体的第二分支（10）。 控制器控制从气体供应朝向鼻部界面的分支（11,10）中的输送，其中流动在第一和第二分支中是单向的。 第一分支（11）包括雾化器（12）和配置成在通过第二分支（10）的流动期间存储气溶胶团的管线。 阀（6）包括一侧的气体入口与另一侧的分支之间的Y形结。

    END-OF-DOSE DETECTION IN NEBULIZERS
    3.
    发明申请
    END-OF-DOSE DETECTION IN NEBULIZERS 审中-公开
    NEBULIZERS中的终端检测

    公开(公告)号：WO2017055166A1

    公开(公告)日：2017-04-06

    申请号：PCT/EP2016/072541

    申请日：2016-09-22

    Applicant: STAMFORD DEVICES LIMITED

    Inventor： GREHAN, Joseph ,  CASEY, Michael ,  PORTER, Shaun ,  SMITH, Niall

    IPC: B05B17/06 ,  A61M11/00

    CPC classification number: B05B17/0646 ,  A61M11/005 ,  A61M2205/3317 ,  A61M2205/3386 ,  B05B12/081 ,  B05B15/14 ,  B05B17/0669 ,  B06B1/0253 ,  B06B2201/77

    Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.

    Abstract translation: 喷雾器控制器的数字处理器控制和监视施加到孔板的驱动电流（I）。 驱动电流被检测为多个测量点中的每一个的一系列离散值，每个测量点具有特定的驱动频率。处理器实时地计算驱动电流与频率的斜率或速率，并另外确定驱动电流的最小值 导致峰值。 处理器在扫描期间使用最小驱动电流的值，并且当孔板变干时也使用最大斜率值来实现剂量结束的可靠预测。

    NEBULIZER VIBRATING APERTURE PLATE DRIVE FREQUENCY CONTROL AND MONITORING
    4.
    发明申请
    NEBULIZER VIBRATING APERTURE PLATE DRIVE FREQUENCY CONTROL AND MONITORING 审中-公开
    NEBULIZER振动孔板驱动频率控制和监测

    公开(公告)号：WO2015010809A1

    公开(公告)日：2015-01-29

    申请号：PCT/EP2014/060723

    申请日：2014-05-23

    Applicant: STAMFORD DEVICES LIMITED

    Inventor： GREHAN, Joseph ,  SMITH, Niall

    IPC: B05B17/06 ,  B05B12/08

    CPC classification number: A61M11/005 ,  A61M11/001 ,  A61M2205/33 ,  A61M2205/3317 ,  B05B12/004 ,  B05B12/081 ,  B05B15/14 ,  B05B17/0646 ,  B05B17/0669 ,  B06B1/0253 ,  G01N29/22 ,  G01N29/42 ,  G06F19/00 ,  G06F19/3456 ,  G16H20/13

    Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2- 4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.

    Abstract translation: 喷雾器具有孔板，安装件，致动器和孔板驱动电路（2-4）。 控制器测量多个测量点中的每一个的电驱动参数，每个测量点具有驱动频率; 并且基于测量点处的参数的值来确定最佳驱动频率以及剂量结束预测。 控制器以规定的次秒间隔执行短扫描，在两个间隔，在具有不同驱动频率的两个测量点处测量驱动电流。 根据这些点的驱动参数测量，控制器确定是否应执行扫描更大数量的测量点的全扫描。 全扫描可为设备提供最佳的驱动频率，同时也为剂量指示结束。

    A NEBULISER SYSTEM
    5.
    发明申请
    A NEBULISER SYSTEM 审中-公开
    NEBULISER系统

    公开(公告)号：WO2010035252A2

    公开(公告)日：2010-04-01

    申请号：PCT/IE2009/000068

    申请日：2009-09-28

    Applicant: STAMFORD DEVICES LIMITED ,  POWER, John ,  DUFFY, Conor ,  SMITH, Niall ,  CLANCY, Dermot, Joseph ,  HYLAND, Kieran

    Inventor： POWER, John ,  DUFFY, Conor ,  SMITH, Niall ,  CLANCY, Dermot, Joseph ,  HYLAND, Kieran

    IPC: A61M11/00 ,  A61M15/00

    CPC classification number: A61M11/005 ,  A61M15/0028 ,  A61M15/003 ,  A61M15/0031 ,  A61M15/0035 ,  A61M15/0085 ,  A61M2205/6045 ,  B05B12/081 ,  B05B17/0646

    Abstract: A nebuliser 1 particularly for home use comprises a housing 2 having an aerosol generator 3 mounted therein. The housing is closed by a hinged cap 4 and has an outlet 5 through which aerosol generated by the generator 3 is delivered. A suitable connector such as a mouthpiece 6 may be connected to the outlet 5. The housing 2 has a receiver for receiving a nebule 8. The receiver comprises a slot 7 which is sized and/or shaped to accommodate only a nebule 8 of predetermined shape and/or size. The nebuliser cap 4 has a nebule opening means which may be in the form of a puncture pin 10 projecting therefrom to pierce the nebule 8 when the cap is moved to the closed position. The pin 10 is hollow or splined to regulate flow from the nebule. The nebuliser 1 also has a switch means for enabling operation of the aerosol generator 3 when the nebule 8 is opened. The switch means comprises a microswitch 12 on the housing which is engageable by a trigger 13 on the cap 4 when the cap is moved to the closed position. Aerosol generated by the aerosol generator 3 is delivered into a chamber defined by the nebuliser housing 2. Air passes into the chamber through air inlets 30. The air entrains the aerosolised medicament and the entrained aerosolised medicament is delivered from the nebuliser through the outlet 5.

    Abstract translation: 特别用于家庭使用的雾化器1包括其中安装有气溶胶发生器3的壳体2。 壳体由铰接盖4封闭，并且具有出口5，由发生器3产生的气雾通过该出口5被输送。 诸如接口管6的合适的连接器可以连接到出口5.壳体2具有用于接收氖8的接收器。接收器包括槽7，槽7的尺寸和/或形状仅适于具有预定形状的氖8 和/或尺寸。 雾化器盖4具有ne形开口装置，其可以是当帽移动到关闭位置时从其突出的穿刺销10的形式刺穿氖8。 销10是中空的或花键的，以调节来自星云的流动。 雾化器1还具有开关装置，用于当氖8打开时能使气溶胶发生器3工作。 开关装置包括壳体上的微型开关12，当盖子移动到关闭位置时，该开关装置可由盖子4上的触发器13接合。 由气溶胶发生器3产生的气雾剂被输送到由雾化器壳体2限定的室中。空气通过空气入口30进入室。空气夹带雾化的药物，并且夹带的雾化的药物从喷雾器通过出口5输送。

    A NEBULISER FOR THE PRODUCTION OF AEROSOLIZED MEDICATION
    6.
    发明公开
    A NEBULISER FOR THE PRODUCTION OF AEROSOLIZED MEDICATION 审中-公开

    公开(公告)号：EP3718585A3

    公开(公告)日：2021-01-13

    申请号：EP20174258.2

    申请日：2004-07-06

    Applicant: Stamford Devices Limited

    Inventor： POWER, John ,  MORAN, Declan ,  DEVERY, Donal ,  O'SULLIVAN, Gavan ,  FINK, James ,  SMITH, Niall

    IPC: A61M11/00 ,  A61M15/00

    Abstract: A nebuliser has a housing (19) having a reservoir (2) for the medicament. An aerosol generator (7) receives the medicament by gravity flow and aerosolizes the medicament. A gas venting inlet (21) permits a gas to enter the nebuliser and forms a mixture with the aerosol. There is a passage (20, 24) through which the mixture of the aerosol and the gas is delivered to an outlet port (24) of the nebuliser. The housing has a baffle (25) to direct the mixture of the gas and the aerosol to the outlet port (24), the baffle having an inclined surface oriented to cause aerosol to flow through the outlet port, the baffle being inclined towards the outlet port

    HUMIDIFICATION IN BREATHING CIRCUITS
    7.
    发明公开
    HUMIDIFICATION IN BREATHING CIRCUITS 审中-公开
    呼吸回路中的加湿

    公开(公告)号：EP3254632A1

    公开(公告)日：2017-12-13

    申请号：EP17181918.8

    申请日：2009-03-27

    Applicant: Stamford Devices Limited

    Inventor： CLANCY, Dermot Joseph ,  DUFFY, Conor ,  GIBBONS, Keith ,  POWER, John ,  SMITH, Niall

    IPC: A61B17/34 ,  A61M16/16 ,  B05B17/06 ,  A61M15/00

    CPC classification number: A61B17/3474 ,  A61M11/005 ,  A61M11/042 ,  A61M15/0085 ,  A61M15/025 ,  A61M16/0833 ,  A61M16/147 ,  A61M16/16 ,  B05B12/081 ,  B05B17/0646 ,  B05B17/0669

    Abstract: A method for humidifying gas in a ventilator circuit 100, 101, 102, 105, 106 comprises aerosolising a humidifying agent such as water or saline using an aerosol generator 2 and delivering the aerosolised humidifying agent to the inspiration line 101 of the ventilator circuit coupled to the respiratory system of a patient. The aerosol generator 2 comprises a vibratable member 40 having a plurality of apertures extending between a first surface and a second surface. A controller 3 controls the operation of aerosol generator 2, for example in response to the flow of air in the inspiration line 101 as detected by a sensor 11.

    Abstract translation: 用于使呼吸机回路100,101,102,105,106中的气体增湿的方法包括使用气溶胶发生器2气雾化诸如水或盐水的增湿剂，并将气雾化的增湿剂递送至呼吸机回路的吸气管线101， 病人的呼吸系统。 气雾发生器2包括具有在第一表面和第二表面之间延伸的多个孔的可振动构件40。 控制器3例如响应于由传感器11检测到的吸气管线101中的空气流动来控制气雾发生器2的操作。

    A HIGH FLOW NASAL THERAPY SYSTEM
    8.
    发明公开
    A HIGH FLOW NASAL THERAPY SYSTEM 审中-公开

    公开(公告)号：EP3785754A1

    公开(公告)日：2021-03-03

    申请号：EP20203692.7

    申请日：2015-04-10

    Applicant: Stamford Devices Limited

    Inventor： MacLOUGHLIN, Ronan ,  SMITH, Niall

    IPC: A61M11/00 ,  A61M15/00 ,  A61M16/00 ,  A61M16/06 ,  A61M16/10 ,  A61M16/14 ,  A61M16/16 ,  A61M16/08 ,  A61M16/20 ,  A61M15/08

    Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.

    A NEBULISER SYSTEM
    10.
    发明公开
    A NEBULISER SYSTEM 有权
    保护BLER系统

    公开(公告)号：EP2349416A2

    公开(公告)日：2011-08-03

    申请号：EP09787422.6

    申请日：2009-09-28

    Applicant: STAMFORD DEVICES LIMITED

    Inventor： POWER, John ,  DUFFY, Conor ,  SMITH, Niall ,  CLANCY, Dermot, Joseph ,  HYLAND, Kieran

    IPC: A61M11/00 ,  A61M15/00

    CPC classification number: A61M11/005 ,  A61M15/0028 ,  A61M15/003 ,  A61M15/0031 ,  A61M15/0035 ,  A61M15/0085 ,  A61M2205/6045 ,  B05B12/081 ,  B05B17/0646

    Abstract: A nebulizer 1 particularly for home use includes a housing 2 having an aerosol generator 3 mounted therein. The housing is closed by a hinged cap 4 and has an outlet 5 through which aerosol generated by the generator 3 is delivered. A suitable connector such as a mouthpiece 6 may be connected to the outlet 5. The housing 2 has a receiver for receiving a nebule 8. The receiver includes a slot 7 which is sized and/or shaped to accommodate only a nebule 8 of predetermined shape and/or size. The nebulizer cap 4 has a nebule opening device which may be in the form of a puncture pin 10 projecting therefrom to pierce the nebule 8 when the cap is moved to the closed position. The pin 10 is hollow or splined to regulate flow from the nebule. The nebulizer 1 also has a switch device for enabling operation of the aerosol generator 3 when the nebule 8 is opened. The switch device comprises a microswitch 12 on the housing which is engageable by a trigger 13 on the cap 4 when the cap is moved to the closed position. Aerosol generated by the aerosol generator 3 is delivered into a chamber defined by the nebulizer housing 2. Air passes into the chamber through air inlets 30. The air entrains the aerosolized medicament and the entrained aerosolized medicament is delivered from the nebulizer through the outlet 5.

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