公开(公告)号：WO2004085992A3

公开(公告)日：2005-03-24

申请号：PCT/US2004008424

申请日：2004-03-19

Applicant: STC UNM ,  ENKE CHRISTIE

Inventor： ENKE CHRISTIE

IPC: G01N20060101 ,  G01N27/64 ,  H01J49/00 ,  H01J49/40 ,  H01J49/42

CPC classification number: H01J49/40 ,  G01N27/622 ,  H01J49/0045

Abstract: A distance of flight (DOF) approach to mass spectroscopy in which the resolution among the various ion masses is accomplished in space rather than time. A separate detector is associated with each ion mass resolution element. The DOF mass spectrometer can serve as one element in a tandem arrangement, which has the capability to produce a full two-dimensional precursor/product spectrum for each bunch of ions extracted from the source. A "distance-of-flight" (DOF) mass analyzer, having an ion storage device (21) means for applying an ion extraction voltage pulse to said storage device (22, 23), a field free region, and detectors (29), is used in combination with time-of-flight (TOF) mass analysis for precursor and product dispersion. All the precursor ions can undergo a mass changing reaction simultaneously, while still retaining the essential information about the particular precursor m/z value from which each product m/z value emanated. Through the use of a two-dimensional detector, all the products ions from all the precursors can be detected for each batch of ions analyzed.

Abstract translation: 距离飞行（DOF）方法到质谱法，其中各种离子质量的分辨率在空间而不是时间内完成。 单独的检测器与每个离子质量分辨率元件相关联。 DOF质谱仪可以作为串联布置的一个元件，其能够为从源提取的每束离子产生完整的二维前体/产物光谱。 具有离子存储装置（21）的“距离飞行”（DOF）质量分析器，用于向所述存储装置（22,23）施加离子提取电压脉冲的装置，无场区域和检测器（29）， ，与前体和产品分散体的飞行时间（TOF）质量分析结合使用。 所有的前体离子可以同时进行质量变化反应，同时仍然保留关于每个产物m / z值发射的特定前体m / z值的基本信息。 通过使用二维检测器，可以对分析的每批离子检测来自所有前体的所有产物离子。

公开(公告)号：EP1618593A4

公开(公告)日：2007-12-05

申请号：EP04757871

申请日：2004-03-19

Applicant: STC UNM

Inventor： ENKE CHRISTIE

IPC: H01J49/40 ,  G01N20060101 ,  G01N27/64 ,  H01J49/00 ,  H01J49/42

CPC classification number: H01J49/40 ,  G01N27/622 ,  H01J49/0045

Abstract: A distance of flight (DOF) approach to mass spectroscopy in which the resolution among the various ion masses is accomplished in space rather than time. A separate detector is associated with each ion mass resolution element. The DOF mass spectrometer can serve as one element in a tandem arrangement which has the capability to produce a full two-dimensional precursor/product spectrum for each bunch of ions extracted from the source. A "distance-of-flight" (DOF) mass analyzer is used in combination with time-of-flight (TOF) mass analysis for precursor and product dispersion. All the precursor ions can undergo a mass changing reaction simultaneously, while still retaining the essential information about the particular precursor m/z value from which each product m/z value emanated. Through the use of a two-dimensional detector, all the products ions from all the precursors can be detected for each batch of ions analyzed.