公开(公告)号：WO02065515A3

公开(公告)日：2003-03-06

申请号：PCT/US0204381

申请日：2002-02-14

Applicant: STC UNM ,  LOPEZ GABRIEL P ,  BRUECK STEVEN R J ,  ISTA LINNEA K ,  O'BRIEN MICHAEL J ,  HERSEE STEPHEN D

Inventor： LOPEZ GABRIEL P ,  BRUECK STEVEN R J ,  ISTA LINNEA K ,  O'BRIEN MICHAEL J ,  HERSEE STEPHEN D

IPC: B01D15/08 ,  B01D57/00 ,  B01L3/00 ,  B81B1/00 ,  C12Q1/00 ,  G01N27/447 ,  G01N30/02 ,  G01N30/52 ,  G01N30/60 ,  H01L21/00

CPC classification number: B01L3/502746 ,  B01L3/502753 ,  B01L2300/0636 ,  B01L2300/0822 ,  B01L2300/0877 ,  B01L2300/0896 ,  B01L2400/086 ,  B82Y15/00 ,  B82Y30/00 ,  G01N27/44791 ,  G01N30/02 ,  G01N30/6065 ,  G01N30/6095 ,  G01N2030/525 ,  Y10T137/2224 ,  Y10T428/249953 ,  Y10T428/249961 ,  Y10T436/2575 ,  B01D15/3833 ,  B01D15/327 ,  B01D15/3804 ,  B01D15/34

Abstract: The present invention provides a matrix comprising an array of nanostructures that exhibit a variation (gradient) in physical properties (such as size or pitch) in at least one direction of the plane containing said array. A method for forming an array having a gradient property is also provided. In addition, a separation method is provided comprising the steps of: providing a matrix comprising an array of nanostructures arranged so that the array has the property of a gradient; and conducting at least one biomolecule separation process to separate biomolecules in a composition containing a plurality of biomolecules using the matrix.

Abstract translation: 本发明提供一种包含纳米结构阵列的矩阵，其在包含所述阵列的平面的至少一个方向上表现出物理性质（例如尺寸或间距）的变化（梯度）。 还提供了一种形成具有梯度特性的阵列的方法。 另外，提供了一种分离方法，其包括以下步骤：提供包括纳米结构阵列的矩阵，所述纳米结构的阵列被布置成使得阵列具有梯度的性质; 并进行至少一个生物分子分离过程以使用该基质分离含有多个生物分子的组合物中的生物分子。

公开(公告)号：WO0239083A3

公开(公告)日：2002-07-11

申请号：PCT/US0142983

申请日：2001-11-06

Applicant: STC UNM ,  BURANDA TIONE ,  HUANG JINMAN ,  PEREZ-LUNA VICTOR H ,  LOPEZ GABRIEL P ,  SIMONS PETER ,  SKLAR LARRY A

Inventor： BURANDA TIONE ,  HUANG JINMAN ,  PEREZ-LUNA VICTOR H ,  LOPEZ GABRIEL P ,  SIMONS PETER ,  SKLAR LARRY A

IPC: G01N21/64 ,  G01N33/542 ,  G01N33/543 ,  C07K16/00 ,  C12M1/34 ,  C12M3/00 ,  C12Q1/00 ,  G01N21/00 ,  G01N33/53 ,  G01N33/544 ,  G01N33/545

CPC classification number: G01N33/542 ,  G01N33/54313

Abstract: The invention provides a sensing device comprising: a vessel; a plurality of sensor beads located within the vessel to form interstitial spaces there through; and a plurality of biomolecules bound to at least at portion of the plurality of beads, each of the biomolecules having a fluorescent tag. A sensing device comprised a suspension of a plurality of sensor beads. The invention also provides a method for detecting the binding of two biomolecules comprising the following steps: providing a plurality of first biomolecules, each of the first biomolecules having a first fluorescent tag; and providing a plurality of second biomolecules, each of the second biomolecules having a second fluorescent tag. The binding step have a pre-complexing total fluorescence and detecting any difference between the pre-complexing total fluorescence and the post-complexing total fluorescence.

Abstract translation: 本发明提供一种感测装置，包括：容器; 位于容器内的多个传感器珠，以在其间形成间隙空间; 并且多个生物分子结合到所述多个珠粒的至少一部分上，每个生物分子具有荧光标签。 感测装置包括多个传感器珠的悬架。 本发明还提供了检测两种生物分子的结合的方法，包括以下步骤：提供多个第一生物分子，每个第一生物分子具有第一荧光标记; 并且提供多个第二生物分子，每个第二生物分子具有第二荧光标记。 结合步骤具有预络合的总荧光并检测预络合总荧光和后络合总荧光之间的任何差异。

公开(公告)号：WO2007001334A3

公开(公告)日：2007-11-29

申请号：PCT/US2005028552

申请日：2005-08-11

Applicant: STC UNM ,  BREVNOV DMITRI A ,  OLSON TIM S ,  LOPEZ GABRIEL P ,  ATANASSOV PLAMEN B

Inventor： BREVNOV DMITRI A ,  OLSON TIM S ,  LOPEZ GABRIEL P ,  ATANASSOV PLAMEN B

IPC: C25D5/20 ,  C25D21/10

CPC classification number: C25D5/44 ,  C23C18/1844 ,  C23C18/54 ,  C23F1/20 ,  C25D11/18

Abstract: Method for treating an aluminum alloy surface for electrodeposition or electroless deposition of a metal or alloy on the surface, the surface is oxidized (e.g. anodized) to form aluminum oxide, and then the oxidized surface is chemically etched to render the surface amenable for electrodeposition or electroless deposition of the metal or alloy thereon. A metallic coating can be electrodeposited or electroless deposited on the treated surface.

Abstract translation: 用于处理铝合金表面以在表面上电沉积或无电沉积金属或合金的方法，表面被氧化（例如阳极氧化）以形成氧化铝，然后氧化表面被化学蚀刻以使表面适于电沉积或 在其上无电沉积金属或合金。 金属涂层可以被电沉积或无电沉积在经处理的表面上。

公开(公告)号：EP2864762A4

公开(公告)日：2016-01-20

申请号：EP13807610

申请日：2013-03-15

Applicant: STC UNM

Inventor： GRAVES STEVEN WAYDE ,  AUSTIN SUTHANTHIRARA PEARLSON PRASHANTH ,  SHREVE ANDREW P ,  LOPEZ GABRIEL P

IPC: G01N15/14 ,  C12Q1/02 ,  G01N21/27

CPC classification number: G01N15/1404 ,  G01N15/1459 ,  G01N2015/142