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    DRY POWDER INHALER WITH AEROELASTIC DISPERSION MECHANISM
    1.
    发明申请
    DRY POWDER INHALER WITH AEROELASTIC DISPERSION MECHANISM 审中-公开
    干粉式吸入器与惰性分散机理

    公开(公告)号：WO2007103152A3

    公开(公告)日：2008-05-02

    申请号：PCT/US2007005312

    申请日：2007-03-01

    Applicant: STC UNM ,  SMYTH HUGH ,  TRUMAN CHARLES RANDALL

    Inventor： SMYTH HUGH ,  TRUMAN CHARLES RANDALL

    IPC: A61M15/00

    CPC classification number: A61M15/0065 ,  A61M15/0003 ,  A61M15/001 ,  A61M15/0028 ,  A61M15/0043 ,  A61M15/0045 ,  A61M15/0051 ,  A61M15/0055 ,  A61M15/0068 ,  A61M2202/064 ,  A61M2205/8275 ,  A61M2206/14 ,  A61M2206/16

    Abstract: The present invention comprises a dry powder inhaler (DPI) that uses a patient's inhalation flow to concentrate energy in an aeroelastic element for deaggregation and dispersion of a powder dose. The result is a DPI that delivers a dose independent of inspiratory abilities of the patient, solving a major problem of conventional DPIs. Increased tension on the aeroelastic element causes higher frequency vibrations and improved powder dispersion. The tension of the aeroelastic element can be modified prior to dispensing the DPI to the patient, allowing for individualization for single patients or groups of patients. In addition, the DPI has features that increase the turbulence of the airflow as it passes through the device, further increasing the dispersion and deaggregation of the powder. The DPI can hold a single dose or multiple doses. The powder doses can be dispensed directly onto the aeroelastic element, or may be in adjacent blister packaging.

    Abstract translation: 本发明包括干粉吸入器（DPI），其使用患者的吸入流将能量集中在气动弹性元件中用于粉末剂量的解聚和分散。 其结果是DPI能够独立于患者的吸气能力，解决常规DPI的主要问题。 气动弹性元件上的增加的张力会导致更高的频率振动和改善的粉末分散。 在将DPI分配给患者之前，可以修改气动弹性元件的张力，从而允许单个患者或患者组的个体化。 此外，DPI具有增加气流在通过装置时的湍流的特征，进一步增加了粉末的分散和解聚。 DPI可以持续单剂量或多剂量。 粉末剂量可以直接分配到气动弹性元件上，或者可以在相邻的吸塑包装中。

    Dry powder inhaler with flutter dispersion member
    3.
    发明专利
    Dry powder inhaler with flutter dispersion member 未知

    公开(公告)号：AU2010319328A1

    公开(公告)日：2012-05-31

    申请号：AU2010319328

    申请日：2010-11-12

    Applicant: STC UNM

    Inventor： SMYTH HUGH D C ,  SELVAM PARTHIBAN ,  TRUMAN CHARLES RANDALL

    IPC: A61M15/00 ,  A61M11/02

    Abstract: A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.

    DRY POWDER INHALER WITH FLUTTER DISPERSION MEMBER
    4.
    发明专利
    DRY POWDER INHALER WITH FLUTTER DISPERSION MEMBER 未知

    公开(公告)号：CA2779488A1

    公开(公告)日：2011-05-19

    申请号：CA2779488

    申请日：2010-11-12

    Applicant: STC UNM

    Inventor： SMYTH HUGH D C ,  SELVAM PARTHIBAN ,  TRUMAN CHARLES RANDALL

    IPC: A61M15/00 ,  A61M11/02

    Abstract: A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.

    DRY POWDER INHALER WITH FLUTTER DISPERSION MEMBER
    6.
    发明申请
    DRY POWDER INHALER WITH FLUTTER DISPERSION MEMBER 审中-公开
    干粉分散剂干粉

    公开(公告)号：WO2011060334A3

    公开(公告)日：2011-09-22

    申请号：PCT/US2010056628

    申请日：2010-11-12

    Applicant: STC UNM ,  SMYTH HUGH D C ,  SELVAM PARTHIBAN ,  TRUMAN CHARLES RANDALL

    Inventor： SMYTH HUGH D C ,  SELVAM PARTHIBAN ,  TRUMAN CHARLES RANDALL

    IPC: A61M15/00 ,  A61M11/02

    CPC classification number: A61M15/0028 ,  A61M11/003 ,  A61M15/0031 ,  A61M15/0038 ,  A61M15/0086 ,  A61M2202/064 ,  A61M2205/0233 ,  A61M2206/16

    Abstract: A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.

    Abstract translation: 一种干粉吸入器，包括限定用于接收一定剂量的粉末药物的腔室的壳体，与腔室流体连通的吸入口，至少一个气流入口，其提供腔室与外壳之间的流体连通，以及颤动元件 并且与一定剂量的粉末状药物相关联。 颤振元件具有靠近至少一个气流入口的张紧的远端和与入口的远端和下游相对的自由近端。 颤振元件构造成响应于通过腔室的气流而振动并使粉末状药物的剂量雾化。

    DRY POWDER INHALER WITH AEROELASTIC DISPERSION MECHANISM
    7.
    发明专利
    DRY POWDER INHALER WITH AEROELASTIC DISPERSION MECHANISM 未知

    公开(公告)号：CA2644679C

    公开(公告)日：2013-12-03

    申请号：CA2644679

    申请日：2007-03-01

    Applicant: STC UNM

    Inventor： SMYTH HUGH ,  TRUMAN CHARLES RANDALL

    IPC: A61M15/00

    Abstract: The present invention comprises a dry powder inhaler (DPI) that uses a patient's inhalation flow to concentrate energy in an aeroelastic element for deaggregation and dispersion of a powder dose. The result is a DPI that delivers a dose independent of inspiratory abilities of the patient, solving a major problem of conventional DPIs. Increased tension on the aeroelastic element causes higher frequency vibrations and improved powder dispersion. The tension of the aeroelastic element can be modified prior to dispensing the DPI to the patient, allowing for individualization for single patients or groups of patients. In addition, the DPI has features that increase the turbulence of the airflow as it passes through the device, further increasing the dispersion and deaggregation of the powder. The DPI can hold a single dose or multiple doses. The powder doses can be dispensed directly onto the aeroelastic element, or may be in adjacent blister packaging.

    Dry powder inhaler with aeroelastic dispersion mechanism
    8.
    发明专利
    Dry powder inhaler with aeroelastic dispersion mechanism 未知

    公开(公告)号：AU2007224178B2

    公开(公告)日：2013-03-07

    申请号：AU2007224178

    申请日：2007-03-01

    Applicant: STC UNM

    Inventor： TRUMAN CHARLES RANDALL ,  SMYTH HUGH

    IPC: A61M15/00

    Abstract: The present invention comprises a dry powder inhaler (DPI) that uses a patient's inhalation flow to concentrate energy in an aeroelastic element for deaggregation and dispersion of a powder dose. The result is a DPI that delivers a dose independent of inspiratory abilities of the patient, solving a major problem of conventional DPIs. Increased tension on the aeroelastic element causes higher frequency vibrations and improved powder dispersion. The tension of the aeroelastic element can be modified prior to dispensing the DPI to the patient, allowing for individualization for single patients or groups of patients. In addition, the DPI has features that increase the turbulence of the airflow as it passes through the device, further increasing the dispersion and deaggregation of the powder. The DPI can hold a single dose or multiple doses. The powder doses can be dispensed directly onto the aeroelastic element, or may be in adjacent blister packaging.

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