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1.发明申请BUNYAVIRUSES WITH SEGMENTED GLYCOPROTEIN PRECURSOR GENES AND METHODS FOR GENERATING THESE VIRUSES 审中-公开具有分离的GLYCOPROTEIN前体基因的芽孢杆菌和产生这些病毒的方法
公开(公告)号：WO2014189372A1
公开(公告)日：2014-11-27
申请号：PCT/NL2014/050321
申请日：2014-05-21
Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK
Inventor： KORTEKAAS, Jeroen Alexander , WICHGERS SCHREUR, Paulus-Jozef , ORESHKOVA, Nadia Dimitrova , MOORMANN, Robertus Jacobus Maria
IPC: C12N7/00
CPC classification number: A61K39/12 , A61K2039/525 , C12N7/00 , C12N2760/12034 , C12N2760/12221 , C12N2760/12234 , C12N2760/12243 , C12N2760/12262
Abstract: Title: Bunyaviruses with segmented glycoprotein precursor genes and methods for generating these viruses Abstract: The invention relates to a bunyavirus, in which separated (NSm)Gn and Gc coding regions are functionally present on two different genome segments, preferably a bunyavirus that comprises a total of at least 4 genome segments. The invention further relates to methods for producing said bunyavirus, and to a composition comprising said bunyavirus and a suitable excipient.
Abstract translation: 标题：具有分段糖蛋白前体基因的布尼亚病毒和产生这些病毒的方法摘要：本发明涉及一种布尼亚病毒，其中分离的（NSm）Gn和Gc编码区功能上存在于两个不同的基因组片段上，优选布尼亚病毒，其包含总数 至少4个基因组片段。 本发明还涉及用于生产所述布尼亚病毒的方法，以及包含所述布尼亚病毒和合适赋形剂的组合物。
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2.发明公开BUNYAVIRUSES WITH SEGMENTED GLYCOPROTEIN PRECURSOR GENES AND METHODS FOR GENERATING THESE VIRUSES 有权BUNYAVIREN MIT SEGMENTIGTENGLYCOPROTEINVORLÄUFERGENENUND VERFAHREN ZUR ERZEUGUNG DIESER VIREN
公开(公告)号：EP2999781A1
公开(公告)日：2016-03-30
申请号：EP14729458.1
申请日：2014-05-21
Applicant: Stichting Dienst Landbouwkundig Onderzoek
Inventor： KORTEKAAS, Jeroen Alexander , WICHGERS SCHREUR, Paulus-Jozef , ORESHKOVA, Nadia Dimitrova , MOORMANN, Robertus Jacobus Maria
IPC: C12N7/00
CPC classification number: A61K39/12 , A61K2039/525 , C12N7/00 , C12N2760/12034 , C12N2760/12221 , C12N2760/12234 , C12N2760/12243 , C12N2760/12262
Abstract: The invention relates to a bunyavirus, in which separated (NSm)Gn and Gc coding regions are functionally present on two different genome segments, preferably a bunyavirus that comprises a total of at least 4 genome segments. The invention further relates to methods for producing said bunyavirus, and to a composition comprising said bunyavirus and a suitable excipient.
Abstract translation: 本发明涉及布尼亚病毒，其中分离的（NSm）Gn和Gc编码区功能性地存在于两个不同的基因组片段上，优选包含总共至少4个基因组片段的布尼亚病毒。 本发明还涉及用于生产所述布尼亚病毒的方法，以及包含所述布尼亚病毒和合适赋形剂的组合物。
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