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    DEVICE SUITABLE FOR DISPENSING LIQUID MEDICAMENT
    3.
    发明申请
    DEVICE SUITABLE FOR DISPENSING LIQUID MEDICAMENT 审中-公开
    适用于分配液体药物的装置

    公开(公告)号：WO2012085937A1

    公开(公告)日：2012-06-28

    申请号：PCT/IN2011/000872

    申请日：2011-12-20

    Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD. ,  KANE, Prashant ,  GOKHALE, Satish Madhukar ,  GOLE, Nachiket

    Inventor： KANE, Prashant ,  GOKHALE, Satish Madhukar ,  GOLE, Nachiket

    IPC: B65D83/76

    CPC classification number: B65D83/0072

    Abstract: The present invention describes a device suitable for dispensing multiple doses of a liquid medicament, the device comprising a) a container having a liquid medicament therein, comprising at least one collapsible wall (3) b) a rotating plunger (7) connected to a push button (8) and c) locking means wherein upon pressing the push button (8), the rotating plunger (7) rotates and traverses from the first position to a traversed position causing preset compression of the collapsible wall of the container (3) to dispense a preset volume of the liquid medicament, and wherein the rotating plunger (7) is locked from returning to the first position by the locking means, thereby preventing air from entering back into the container to maintain a sterile environment within the container (3).

    Abstract translation: 本发明描述了一种适于分配多剂量液体药物的装置，该装置包括a）在其中具有液体药物的容器，包括至少一个可折叠壁（3），b）连接到推动件的旋转柱塞（7） 按钮（8）和c）锁定装置，其中在按压按钮（8）时，旋转柱塞（7）从第一位置旋转并且从第一位置移动到穿过位置，从而使容器（3）的可折叠壁的预设压缩 分配液体药物的预设体积，并且其中旋转柱塞（7）通过锁定装置被锁定以返回到第一位置，从而防止空气返回到容器中以将无菌环境保持在容器（3）内， 。

    NANOPARTICULATE COMPOSITION
    4.
    发明申请
    NANOPARTICULATE COMPOSITION 审中-公开
    纳米颗粒组合物

    公开(公告)号：WO2016135754A1

    公开(公告)日：2016-09-01

    申请号：PCT/IN2016/050068

    申请日：2016-02-25

    Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD

    Inventor： BOMMAGANI, Madhusudhan ,  BHOWMICK, Subhas Balaram ,  KANE, Prashant ,  DUBEY, Vaibhav

    IPC: A61K9/00 ,  A61K9/06 ,  A61K9/12 ,  A61K9/51 ,  A61K31/65

    CPC classification number: A61K9/146 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/10 ,  A61K9/122 ,  A61K31/65 ,  A61K47/14 ,  Y02A50/473

    Abstract: The present invention relates to a nanoparticulate topical composition comprising (i) nanoparticles of a water soluble and water susceptible active ingredient or its pharmaceutically acceptable salt, having a particle size distribution such that 90% of the particles are less than 1000 nm, (ii) one or more wetting agent and (iii) a non-aqueous liquid vehicle, wherein the composition is free of water. The present invention also relates to a method of treating acne, rosacea, impetigo or a skin disease caused by a bacteria, by topical application of a nanoparticulate topical composition comprising nanoparticles of a water soluble and water susceptible active ingredient or its pharmaceutically acceptable salt, having a particle size distribution such that 90% of the particles are less than 1000 nm.

    Abstract translation: 本发明涉及纳米颗粒局部组合物，其包含（i）水溶性和水易感活性成分或其药学上可接受的盐的纳米颗粒，其粒度分布使得90％的颗粒小于1000nm，（ii） 一种或多种润湿剂和（iii）非水液体载体，其中所述组合物不含水。 本发明还涉及通过局部施用包含水溶性和水敏感活性成分或其药学上可接受的盐的纳米颗粒的纳米颗粒局部组合物来治疗由细菌引起的痤疮，红斑痤疮，脓疱病或皮肤病的方法，其具有 使得90％的颗粒小于1000nm的粒度分布。

    DRY POWDER INHALATION COMPOSITION
    9.
    发明公开
    DRY POWDER INHALATION COMPOSITION 审中-公开
    TROCKENPULVERINHALATIONSZUSAMMENSETZUNG

    公开(公告)号：EP2571486A1

    公开(公告)日：2013-03-27

    申请号：EP11783170.1

    申请日：2011-05-13

    Applicant: Sun Pharma Advanced Research Company Ltd

    Inventor： BHOWMICK, Subhas ,  KANE, Prashant ,  S, Ganesh ,  PATEL, Tarun ,  CHUDIWAL, Swapnil

    IPC: A61K9/00 ,  A61K31/137

    CPC classification number: A61K31/137 ,  A61K9/0075 ,  A61K9/145

    Abstract: The dry powder inhalation composition comprising (1) salmeterol xinafoate having mean particle size in range of 2.0μ-6μ microns and a tapped density in the range of 0.20 g·cm−3 to 0.45 g·cm−3 and (2) optionally, one or more other active ingredients and pharmaceutically acceptable carrier.

    Abstract translation: 所述干粉吸入组合物包含（1）平均粒径为2.0μ-6μ微米的海洛英醇海绵酸新甲酯，并且在0.20g·cm -3〜0.45g·cm -3的范围内的抽头密度和（2）任选地， 一种或多种其它活性成分和药学上可接受的载体。

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