公开(公告)号：CA2947392A1

公开(公告)日：2015-11-05

申请号：CA2947392

申请日：2015-04-29

Applicant: THERALASE TECH INC

Inventor： DUMOULIN-WHITE ROGER ,  EMBREE WAYNE ,  MANDEL ARKADY

IPC: A61N5/06 ,  A61K41/00 ,  A61N5/08 ,  A61P35/00

Abstract: A method for treating a condition in a tissue, includes the steps: (1 ) providing a PS within the tissue; (2) irradiating the tissue containing the PS with a first light of a first wavelength; and (3) irradiating the tissue containing the PS with a second light of a second wavelength so as to treat the condition in the tissue, wherein: (a) the PS absorbs light at the first wavelength and the second wavelength; and (b) the second light is more strongly absorbed by the tissue than the first light or vice versa, so as to achieve a predetermined absorbed photon density gradient. An apparatus for conducting the method includes first and second light sources, a power supply, a focusing device, and a controller which adjusts light emission such that 1(d) = ?(?1 at d=0) x exp (µeff (?1) x d) + ?(?2 at d=0) x exp (µeff(?2) ? d).

公开(公告)号：CA3001273A1

公开(公告)日：2017-04-13

申请号：CA3001273

申请日：2016-10-10

Applicant: THERALASE TECH INC ,  UNIV HEALTH NETWORK ,  UNIV HEALTH NETWORK

Inventor： LIGLE LOTHAR ,  DUMOULIN-WHITE ROGER ,  EMBREE WAYNE ,  LEM DON ,  MANDEL ARKADY ,  WU JENNY

IPC: A61N5/06 ,  A61B1/07 ,  A61B1/307 ,  G02B6/42

Abstract: Apparatus for illuminating comprises one or more fibers, the one or more fibers including fiber portions meeting at an apex and a bottom location to form a three dimensional cage; a detector attached to each of the fiber portions for receiving light and transmitting light along each of the fiber portions, respectively; and an illumination member situated within the cage. A method for illuminating a hollow member includes the steps of inserting one or more fibers into the hollow member, wherein one or more fibers include fiber portions that meet at a location to form a three-dimensional cage; permitting light to emit from within the three-dimensional cage and towards the fiber portions; receiving light at distinct locations on each of said fibers; and allowing each of the fibers to transmit the light received on each of the fiber portions out of the hollow member.

公开(公告)号：CA2947392C

公开(公告)日：2022-11-01

申请号：CA2947392

申请日：2015-04-29

Applicant: THERALASE TECH INC

Inventor： DUMOULIN-WHITE ROGER ,  EMBREE WAYNE ,  MANDEL ARKADY

IPC: A61N5/06 ,  A61N5/08 ,  A61P35/00

Abstract: A method for treating a condition in a tissue, includes the steps: (1 ) providing a PS within the tissue; (2) irradiating the tissue containing the PS with a first light of a first wavelength; and (3) irradiating the tissue containing the PS with a second light of a second wavelength so as to treat the condition in the tissue, wherein: (a) the PS absorbs light at the first wavelength and the second wavelength; and (b) the second light is more strongly absorbed by the tissue than the first light or vice versa, so as to achieve a predetermined absorbed photon density gradient. An apparatus for conducting the method includes first and second light sources, a power supply, a focusing device, and a controller which adjusts light emission such that 1(d) = ?(?1 at d=0) x exp (µeff (?1) x d) + ?(?2 at d=0) x exp (µeff(?2) ? d).

公开(公告)号：EP3137165A4

公开(公告)日：2018-02-14

申请号：EP15786751

申请日：2015-04-29

Applicant: THERALASE TECH INC

Inventor： LILGE LOTHAR ,  MANDEL ARKADY ,  DUMOULIN-WHITE ROGER ,  EMBREE WAYNE

IPC: A61N5/06 ,  A61K41/00 ,  A61N5/08 ,  A61P35/00

CPC classification number: A61N5/062 ,  A61B2018/2035 ,  A61B2018/2065 ,  A61K41/0057 ,  A61N5/0616 ,  A61N2005/0626 ,  A61N2005/0651 ,  A61N2005/0652 ,  A61N2005/0659 ,  A61N2005/0662 ,  A61N2005/067

Abstract: A method for treating a condition in a tissue, includes the steps: (1) providing a PS within the tissue; (2) irradiating the tissue containing the PS with a first light of a first wavelength; and (3) irradiating the tissue containing the PS with a second light of a second wavelength so as to treat the condition in the tissue, wherein: (a) the PS absorbs light at the first wavelength and the second wavelength; and (b) the second light is more strongly absorbed by the tissue than the first light or vice versa, so as to achieve a predetermined absorbed photon density gradient. An apparatus for conducting the method includes first and second light sources, a power supply, a focusing device, and a controller which adjusts light emission such that I(d)=I(λ1 at d=0)×exp (μeff (λ1)×d)+I(λ2 at d=0)×exp (μeff(λ2)χd).