公开(公告)号：JPS5111946A

公开(公告)日：1976-01-30

申请号：JP8015874

申请日：1974-07-15

Applicant: TORAY INDUSTRIES

Inventor： OOTAKI YUKIO ,  MINEO MASANORI ,  NAKAGAWA KYOSHI ,  SAIKAI SHIRO ,  ARATANI YOSHIO

IPC: D02G1/00 ,  D02G1/18 ,  D02G3/24

公开(公告)号：JPS5929694B2

公开(公告)日：1984-07-23

申请号：JP5990077

申请日：1977-05-25

Applicant: Toray Industries

Inventor： ARAYA YOSHIO ,  SUZUKI MASAO ,  SAIKAI SHIRO

IPC: D04B1/14 ,  D01F6/54 ,  D03D15/00

公开(公告)号：JPH0533688B2

公开(公告)日：1993-05-20

申请号：JP22197884

申请日：1984-10-24

Applicant: TORAY INDUSTRIES

Inventor： KODAMA MASATOMO ,  TANI TOORU ,  SAIKAI SHIRO ,  SUZUKI JIRO ,  TERAMOTO KAZUO

IPC: A61K35/14 ,  A61K38/16 ,  A61K38/17 ,  A61P35/00

公开(公告)号：JPS589166B2

公开(公告)日：1983-02-19

申请号：JP8865874

申请日：1974-08-03

Applicant: TORAY INDUSTRIES

Inventor： UCHIDA AKIRA ,  SAIKAI SHIRO ,  ISHIBASHI HIDEO

IPC: D01F8/14

公开(公告)号：JPS51102325A

公开(公告)日：1976-09-09

申请号：JP2646275

申请日：1975-03-05

Applicant: TORAY INDUSTRIES

Inventor： TAKASE HIDEO ,  ISHII TOYOTA ,  SAIKAI SHIRO

IPC: B32B5/00 ,  A47G27/02 ,  B32B5/16 ,  B32B9/04

公开(公告)号：JPH0335974B2

公开(公告)日：1991-05-30

申请号：JP6328484

申请日：1984-04-02

Applicant: TORAY INDUSTRIES

Inventor： KODAMA MASATOMO ,  TANI TOORU ,  HANAZAWA KAZUYOSHI ,  OKA FUJITARO ,  TERAMOTO KAZUO ,  SAIKAI SHIRO

IPC: B01J20/26 ,  A61K38/00 ,  A61M1/36

公开(公告)号：JPS6214672B2

公开(公告)日：1987-04-03

申请号：JP9027377

申请日：1977-07-29

Applicant: TORAY INDUSTRIES

Inventor： TAKASE HIDEO ,  SAIKAI SHIRO

IPC: D06N7/00 ,  D06N7/04

公开(公告)号：JPS6014121B2

公开(公告)日：1985-04-11

申请号：JP4264477

申请日：1977-04-15

Applicant: TORAY INDUSTRIES

Inventor： HAYAKAWA KUNIAKI ,  ARAYA YOSHIO ,  SAIKAI SHIRO

IPC: D01F6/60 ,  D01F6/62 ,  D02J1/06 ,  D02J1/22

公开(公告)号：JPH05329207A

公开(公告)日：1993-12-14

申请号：JP262593

申请日：1993-01-11

Applicant: TORAY INDUSTRIES

Inventor： KODAMA MASATOMO ,  TANI TORU ,  HANAZAWA KAZUYOSHI ,  OKAFUJI TARO ,  TERAMOTO KAZUO ,  SAIKAI SHIRO

IPC: A61K47/00 ,  A61K9/70 ,  A61K47/30 ,  A61M1/14 ,  A61M1/36 ,  B01D15/08 ,  B01J20/28 ,  B01J20/32

Abstract: PURPOSE:To weaken a side effect while taking advantage of the endotoxin neutralizing effect of polymixin by immobilizing the polymixin on a fibrous carrier having the substituent selected from an alpha-acyl halide group, benzyl halide group and isocyanic acid group, thereby preparing the endotoxin neutralizer. CONSTITUTION:The endotoxin neutralizer is prepd. by immobilizing the polymixin to the fibrous carrier having the substituent selected from the alpha-acyl halide group, the benzyl halide group and the isocyanic acid group. The fibrous carrier is selected from polystyrene fibers or crosslinked polystyrene fibers, acrylic acid acrylonitride copolymer fibers and polyvinyl alcohol fibers having a carboxyl group. Since the endotoxin neutralizer is formed by immobilizing the polymixin at a high density, the neutralizer is capable of decomposing and nontoxicating the endotoxin in a soln. Since the polymixin does not elute into the soln., the soln. treated with the neutralizer does not exhibit toxicity.

公开(公告)号：JPS51102177A

公开(公告)日：1976-09-09

申请号：JP2645775

申请日：1975-03-05

Applicant: TORAY INDUSTRIES

Inventor： TAKASE HIDEO ,  ISHII TOYOTA ,  SAIKAI SHIRO

IPC: B05C11/08 ,  B05D1/28 ,  B05D1/40 ,  B05D3/12 ,  D06M15/00