公开(公告)号：DE19811092A1

公开(公告)日：1998-11-26

申请号：DE19811092

申请日：1998-03-13

Applicant: TOSOH CORP

Inventor： NAGAI RYUICHIRO ,  KUBO MASASHIGE ,  AWANO HIROSHI ,  MIYANO OSAMU

IPC: C07C209/62 ,  C07C211/27

公开(公告)号：GB2323087A

公开(公告)日：1998-09-16

申请号：GB9805300

申请日：1998-03-12

Applicant: TOSOH CORP

Inventor： NAGAI RYUICHIRO ,  KUBO MASASHIGE ,  AWANO HIROSHI ,  MIYANO OSAMU

IPC: C07C209/62 ,  C07C211/27 ,  C07C209/74

Abstract: A process for producing a benzylamine salt of the formula (1): wherein, R is hydrogen, halogen atom, trifluoromethyl group or lower alkyl group; and M is a counter-ion of the benzylammonium ion having a valency of n; comprising the step of hydrolysing a quaternary ammonium salt obtained by reacting benzyl bromide of the formula (2) wherein, R is hydrogen, halogen atom, trifluoromethyl group or lower alkyl group; with hexamethylenetetramine in an alcohol/water mixed solvent is provided. Crystals of above compounds of formula (1) having a short axis length of 10-30 mm and long axis length of 20-150 mm and a purity of 99% are also claimed.

公开(公告)号：GB2323087B

公开(公告)日：2000-09-06

申请号：GB9805300

申请日：1998-03-12

Applicant: TOSOH CORP

Inventor： NAGAI RYUICHIRO ,  KUBO MASASHIGE ,  AWANO HIROSHI ,  MIYANO OSAMU

IPC: C07C209/62 ,  C07C211/27 ,  C07C209/74

公开(公告)号：JPH0539240A

公开(公告)日：1993-02-19

申请号：JP21663091

申请日：1991-08-02

Applicant: TOSOH CORP

Inventor： NAGAI RYUICHIRO ,  MIYAKI KATSUYOSHI

IPC: B01J27/10 ,  B01J27/128 ,  B01J31/04 ,  C07B61/00 ,  C07C41/01 ,  C07C43/225

Abstract: PURPOSE:To produce fluoroalkoxybenzenes from bromofluorobenzenes having large reaction accelerating effect with both reduced metal alkoxide amount and catalyst amount while maintaining high yield. CONSTITUTION:Bromofluorobnezne is reacted with an aliphatic or aromatic metal alkoxide in the presence of a catalyst of copper and/or cobalt compounds in an aliphatic or aromatic alcohol solvent in the coexistence of at least one kind of compound selected between a beta-diketone compound and nitrogen- containing heteroaromatic compound to provide the objective fluoroalkoxybenzene.

公开(公告)号：JPH10310562A

公开(公告)日：1998-11-24

申请号：JP8049598

申请日：1998-03-13

Applicant: TOSOH CORP

Inventor： NAGAI RYUICHIRO ,  KUBO MASAJI ,  AWANO YUTAKA ,  MIYANO OSAMU

IPC: C07C209/08 ,  C07C211/63

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound large in the diameters of its crystals and useful as an intermediate for synthesizing dyestuffs, agrochemicals, medicines, etc., in a high yield and in a high purity by reacting a benzyl bromide with hexamethylenetetramine and subsequently hydrolyzing the obtained ammonium salt in the presence of an acid in an alcohol-water mixture solvent. SOLUTION: This method for producing a benzylamine salt of formula II (M is a counter ion of n-valent benylammonium ion) comprises thermally reacting a benzyl bromide of formula I (R is H, a halogen, trifluoromethyl, etc.) such as benzyl bromide or 2-bromobenyzl bromide with the equivalent amount of hexamethylenetetramine, hydrolyzing the obtained quaternary ammonium salt in the presence of an acid, e.g. an inorganic acid such as hydrochloric acid, nitric acid or sulfuric acid in the water mixture solvent with a low boiling point alcohol such as methanol, ethanol or propanol preferably at 15-50 deg.C, filtering off the generated crystals and subsequently washing the obtained crystals with water or a diluted acid.

公开(公告)号：JPH061729A

公开(公告)日：1994-01-11

申请号：JP17884692

申请日：1992-06-15

Applicant: TOSOH CORP

Inventor： NAGAI RYUICHIRO ,  SEKI KOJI ,  SATO MASAKATSU ,  YANAGIHARA TADAHISA ,  NODA MITSURU

IPC: B01J27/138 ,  C07B61/00 ,  C07C17/16 ,  C07C17/38 ,  C07C19/02

Abstract: PURPOSE:To provide a production method for alkyl chlorides raised in reaction rate with the inclusion of much water into the synthetic system avoided. CONSTITUTION:The production method is characterized by that reaction A is made continuously between a 4-8C alkyl alcohol and hydrogen chloride in the presence or absence of a catalyst, and the reaction product distilled off is separated B into an aqueous layer and an organic layer consisting mainly of an alkyl chloride followed by adding water to the aqueous layer in a hydrochloric acid concentration regulating tank C to regulate the hydrochloric acid concentration based on the water at