公开(公告)号：JPH11130708A

公开(公告)日：1999-05-18

申请号：JP29829597

申请日：1997-10-30

Applicant: TOSOH CORP

Inventor： AWANO YUTAKA ,  SHIMODA ATSUSHI ,  KUBO MASAJI

IPC: B01J31/02 ,  C07B39/00 ,  C07B61/00 ,  C07C17/14 ,  C07C22/08 ,  C07C25/02 ,  C07C63/70 ,  C07C201/12 ,  C07C205/11 ,  C07C255/50

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing a monobromomethylated aromatic compound, capable of solving a problem that the selectivity of the monobromomethylated product is low by conventional methods, and capable of efficiently obtaining the monobromomethylated aromatic compound by an industrially simple method without using a special device such as a photoreactor or the like. SOLUTION: This method for producing a monobromomethylated aromatic compound comprises brominating a methyl group bound to the aromatic ring of a substituted aromatic compound of the formula (R is at least one electron- attracting substituent selected from nitro group, a halogen atom, trifluoromethyl group, cyano group, carboxyl group, an alkoxycarbony group and phenoxy group). Therein, the reaction is carried out in the presence of water and one or more kinds of radical initiators selected from the group consisting of dialkyl peoxides, diacyl peroxide and azo compounds.

公开(公告)号：JPH11199536A

公开(公告)日：1999-07-27

申请号：JP147798

申请日：1998-01-07

Applicant: TOSOH CORP

Inventor： SHIMODA ATSUSHI ,  KUBOTA MASAHIRO ,  AWANO YUTAKA ,  KUBO MASAJI

IPC: B01J31/02 ,  C07B61/00 ,  C07C45/43 ,  C07C45/80 ,  C07C47/54 ,  C07C47/542 ,  C07C47/55 ,  C07C47/575 ,  C07C201/12 ,  C07C205/44

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing a benzaldehyde compound, capable of improving a hydrolysis rate, when a (non)substituted benzal halide compound and water are mixed and heated, by using a specific catalyst without using a metal salt catalyst. SOLUTION: This method for producing a benzaldehyde compound comprises hydrolyzing a (non)substituted benzal halide compound. Therein, the hydrolysis reaction is carried out in the presence of a catalyst (preferably toluenesulfonic acid) having affinity with water and/or the benzal halide compound. Preferably, a benzal halide compound of formula I [X is a halogen; Y is a halogen, nitro or the like; (n) is 0-5] such as benzal chloride is hydrolyzed to obtain a benzaldehdye of formula II. The catalyst is preferably added in an amount of 0.1-30 mol.% per mole of the benzal halide compound, and the water is allowed to coexist in an amount of 150-300 g on the hydrolysis reaction. The reaction is preferably performed in an atmosphere of nitrogen, because the product is easily oxidized. The reaction temperature is preferably 80-160 deg.C.

公开(公告)号：JP2002179600A

公开(公告)日：2002-06-26

申请号：JP2000379783

申请日：2000-12-08

Applicant: TOSOH CORP

Inventor： SHIMODA ATSUSHI ,  TABAKOTANI HIROSHI ,  AWANO YUTAKA ,  KUBO MASAJI

IPC: C07C29/62 ,  C07B61/00 ,  C07C29/80 ,  C07C29/86 ,  C07C31/36

Abstract: PROBLEM TO BE SOLVED: To provide a method for easily, industrially and efficiently producing high-purity 3-chloro-1-propanol free from impurities including its ether modification by selectively chlorinating 1,3-propanediol with hydrochloric acid or a hydrogen chloride gas as the hydrogen chloride source. SOLUTION: This method for producing high-purity 3-chloro-1-propanol comprises the steps of reacting a hydrogen chloride source with 1,3-propanediol at 60-100 deg.C to obtain a reaction liquid containing 3-chloro-1-propanol and then extracting and removing impurities present in the reaction liquid with a hydrophobic organic solvent.