公开(公告)号：US20230408805A1

公开(公告)日：2023-12-21

申请号：US18205152

申请日：2023-06-02

Applicant: Trustees of Boston University

Inventor： Ji-Xin Cheng ,  Celalettin Yurdakul ,  Haonan Zong ,  M. Selim Ünlü

IPC: G02B21/16 ,  G02B21/02 ,  G02B21/36

CPC classification number: G02B21/16 ,  G02B21/025 ,  G02B21/361

Abstract: Microscopic analysis of a sample includes a system using dark-field illumination. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. A visible light source generates a light illuminating the sample on a substrate and creating a scattered field and a reflected field along a collection path of the system. A pupil mask is positioned along the collection path to block the reflected field while allowing the scattered field to pass therethrough. A camera is positioned at an end of the collection path to collect the scattered field and generate a dark-field image of the sample.

公开(公告)号：US11709352B2

公开(公告)日：2023-07-25

申请号：US17704896

申请日：2022-03-25

Applicant: Trustees of Boston University

Inventor： Ji-Xin Cheng ,  Celalettin Yurdakul ,  Haonan Zong ,  M. Selim Ünlü

IPC: G02B21/16 ,  G02B21/02 ,  G02B21/36

CPC classification number: G02B21/16 ,  G02B21/025 ,  G02B21/361

Abstract: Microscopic analysis of a sample includes a system using dark-field illumination. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. A visible light source generates a light illuminating the sample on a substrate and creating a scattered field and a reflected field along a collection path of the system. A pupil mask is positioned along the collection path to block the reflected field while allowing the scattered field to pass therethrough. A camera is positioned at an end of the collection path to collect the scattered field and generate a dark-field image of the sample.

公开(公告)号：US20250012557A1

公开(公告)日：2025-01-09

申请号：US18761623

申请日：2024-07-02

Applicant: Trustees of Boston University

Inventor： Ji-Xin Cheng ,  Haonan Zong ,  Celalettin Yurdakul ,  M. Selim Ünlü

IPC: G01B9/02091

Abstract: A wide-field bond-selective optical coherence tomography (OCT) system and method for imaging a sample includes generating infrared light and directing the infrared light onto the sample to selectively heat the sample. Probe light is also directed onto the sample. A first actuator provides sample depth scanning with respect to a first objective in a reference arm of the system, and a second actuator provides sample depth scanning with respect to a second objective in a sample arm of the system. A detection system receives scattered probe light reflected from the sample. A change in the received probe light from the sample that is indicative of absorption of infrared light.

公开(公告)号：US12147022B2

公开(公告)日：2024-11-19

申请号：US18205152

申请日：2023-06-02

Applicant: Trustees of Boston University

Inventor： Ji-Xin Cheng ,  Celalettin Yurdakul ,  Haonan Zong ,  M. Selim Ünlü

IPC: G02B21/16 ,  G02B21/02 ,  G02B21/36

Abstract: Microscopic analysis of a sample includes a system using dark-field illumination. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. A visible light source generates a light illuminating the sample on a substrate and creating a scattered field and a reflected field along a collection path of the system. A pupil mask is positioned along the collection path to block the reflected field while allowing the scattered field to pass therethrough. A camera is positioned at an end of the collection path to collect the scattered field and generate a dark-field image of the sample.

公开(公告)号：US20220308327A1

公开(公告)日：2022-09-29

申请号：US17704896

申请日：2022-03-25

Applicant: Trustees of Boston University

Inventor： Ji-Xin Cheng ,  Celalettin Yurdakul ,  Haonan Zong ,  M. Salim Unlü

IPC: G02B21/16 ,  G02B21/36 ,  G02B21/02

Abstract: Microscopic analysis of a sample includes a system using dark-field illumination. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. A visible light source generates a light illuminating the sample on a substrate and creating a scattered field and a reflected field along a collection path of the system. A pupil mask is positioned along the collection path to block the reflected field while allowing the scattered field to pass therethrough. A camera is positioned at an end of the collection path to collect the scattered field and generate a dark-field image of the sample.