公开(公告)号：EP3146534A4

公开(公告)日：2018-04-18

申请号：EP15795336

申请日：2015-05-18

Applicant: UNIV CALIFORNIA

Inventor： PEGAN JONATHAN ,  KHINE MICHELLE ,  BACHMAN MARK ,  KIM JOSHUA ,  PARK SUN JUN

IPC: H01B7/06 ,  G01L1/22

CPC classification number: G01B7/20 ,  A61B5/113 ,  A61B2562/0261 ,  A61B2562/0285 ,  A61B2562/164 ,  G01L1/2287

Abstract: A sensor apparatus including a flexible substrate and a wrinkled conductor disposed on the flexible substrate. In some embodiments, the conductor includes micro-scale invaginations. Also disclosed are methods of making a sensor apparatus, including: placing a mask over a polymeric sheet, wherein the mask is configured to block regions of the polymeric sheet, depositing a conductive structure on the polymeric sheet at regions exposed through the mask, shrinking the polymeric sheet with conductive structure patterned on its surface by heating, and transferring the conductive structure to a flexible substrate. Also disclosed are methods of sensing a health condition of a user or patient. The methods include coupling a sensor apparatus to a surface of a user or patient overlying structures to be monitored. The sensor apparatus may include a crumpled conductor capable of detecting strain. Strain is detected by directing current through the sensor apparatus during flexing of the surface and measuring a characteristic of the sensor apparatus based on the strain to generate an output for a user, indicative of the condition of the user or patient.

公开(公告)号：WO2015179322A2

公开(公告)日：2015-11-26

申请号：PCT/US2015031442

申请日：2015-05-18

Applicant: UNIV CALIFORNIA ,  FORDE GARETH ,  LIGON DORSEY

Inventor： FORDE GARETH ,  LIGON DORSEY ,  KHINE MICHELLE ,  PEGAN JONATHAN ,  LEE EUGENE ,  BACHMAN MARK ,  KIM JOSHUA ,  PARK SUN-JUN

IPC: A61B5/02 ,  G06F19/00

CPC classification number: A61B5/11 ,  A61B5/6833 ,  A61B2503/02 ,  A61B2562/0261 ,  G06F19/3418 ,  G06F19/345 ,  G16H50/20

Abstract: A wearable sensor apparatus is disclosed that includes a flexible substrate adapted to be coupled with a skin surface of an expectant mother, A conductor is disposed on the flexible substrate. The conductor can include micron-scale invaginations. The conductor can be capable of repeatable variation in resistance when subject to a strain. Also disclosed is a system for monitoring the health of a fetus in utero that includes a wearable sensor apparatus. The wrearable sensor apparatus is configured to output a signal responsive to an electrical input. The system includes a computing system with one or more hardware processors. The computing system is programmed to implement a signal processing module configured to access the output, signal from the wearable strain gauge and generate an output indicative of health of the baby in utero. The output can be based in part on the received output signal and previously stored correlations between signal data from the wearable strain gauge and observations of the system or of the mother. A user interface module can be provided and can be configured to display an output indicative of health of the baby in utero.

Abstract translation: 公开了一种可穿戴传感器装置，其包括适于与预期母亲的皮肤表面耦合的柔性基底.A导体设置在柔性基底上。 导体可以包括微米级的内陷。 当受到应变时，导体能够具有可重复的电阻变化。 还公开了一种用于监测子宫内的胎儿的健康状况的系统，其包括可穿戴传感器装置。 可疑传感器装置被配置为响应于电输入而输出信号。 该系统包括具有一个或多个硬件处理器的计算系统。 计算系统被编程为实现信号处理模块，该信号处理模块被配置为访问来自可穿戴应变计的输出信号，并产生指示婴儿在子宫内的健康的输出。 输出部分可以部分地基于所接收的输出信号和先前存储的来自可穿戴应变计的信号数据与系统或母体的观察结果之间的相关性。 可以提供用户界面模块并且可以被配置为在子宫内显示指示婴儿健康的输出。

公开(公告)号：CA3119064A1

公开(公告)日：2020-05-14

申请号：CA3119064

申请日：2019-11-08

Applicant: UNIV CALIFORNIA

Inventor： WASHINGTON GREGORY ,  SMITH THERON FREDERICK LEE ,  ELLINGTON FLORANNE TAVAILAU ,  KHINE MICHELLE ,  KIM JOSHUA ,  GARCIA JOSEPH

IPC: G06F3/01 ,  A61B5/021

Abstract: Soft capacitive pressure sensors for continuous wearable health monitoring applications are described herein. Wrinkled gold thin films on elastomeric substrates are used as robust parallel plate electrodes to create a robust integration with the polymer, allowing repeated normal force to deform the thin film without failure. By incorporating micro-ridged structures that support the counter electrodes to create air cavities within the elastomeric dielectric layer, pressure sensitivity is further increased. The pressure sensors are configured to measure human physiological signals such as pressure exerted from a radial pulse on a skin's surface. The radial pulse pressure detected by the sensor can be correlated to an arterial blood pressure. Calibration of said pressure sensors using a neural network allows for determination of absolute blood pressure.