公开(公告)号：CA2917077A1

公开(公告)日：2015-01-08

申请号：CA2917077

申请日：2014-07-02

Applicant: UNIV HEALTH NETWORK

Inventor： MAK TAK W ,  LAI XIUQIU ,  TUSCHE MICHAEL W

IPC: C07K16/28

Abstract: The present invention provides methods and compositions for modulating Toso activity and treating diseases and disorders in which Toso is implicated. Such methods and compositions include the use of one or more antibodies that bind to a Toso protein or to a ligand of a Toso protein.

公开(公告)号：AU2014286869A1

公开(公告)日：2016-02-11

申请号：AU2014286869

申请日：2014-07-02

Applicant: UNIV HEALTH NETWORK

Inventor： MAK TAK W ,  LAI XIUQIU ,  TUSCHE MICHAEL W

IPC: C07K16/28 ,  A61K39/395 ,  C07K16/46 ,  C12N15/13 ,  C12N15/63 ,  C12P21/08

Abstract: The present invention provides methods and compositions for modulating Toso activity and treating diseases and disorders in which Toso is implicated. Such methods and compositions include the use of one or more antibodies that bind to a Toso protein or to a ligand of a Toso protein.

公开(公告)号：EP3016982A4

公开(公告)日：2017-02-22

申请号：EP14820663

申请日：2014-07-02

Applicant: UNIV HEALTH NETWORK

Inventor： MAK TAK W ,  LAI XIUQIU ,  TUSCHE MICHAEL W

IPC: C07K16/28 ,  A61K39/395 ,  C07K16/46 ,  C12N15/13 ,  C12N15/63 ,  C12P21/08

CPC classification number: C07K16/2803 ,  C07K2317/622