公开(公告)号：CA2927612C

公开(公告)日：2022-08-30

申请号：CA2927612

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00 ,  C07D413/14

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

公开(公告)号：AU2014336917A1

公开(公告)日：2016-05-05

申请号：AU2014336917

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: C07D413/14 ,  A61K31/416 ,  A61K31/5377 ,  A61P35/00

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

公开(公告)号：CA2927612A1

公开(公告)日：2015-04-23

申请号：CA2927612

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00 ,  C07D413/14

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

公开(公告)号：EP3057593A4

公开(公告)日：2017-03-08

申请号：EP14853347

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00

CPC classification number: A61K31/5377 ,  A61K31/7068 ,  A61K33/24 ,  A61K45/06 ,  C07D403/08 ,  C07D413/14 ,  A61K2300/00

公开(公告)号：ES2908200T3

公开(公告)日：2022-04-28

申请号：ES14853347

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00

Abstract: Un compuesto de fórmula estructural (I): **(Ver fórmula)** o una sal farmacéuticamente aceptable del mismo, en el que: cada Ra es independientemente -H o metilo; R1 es -H o metoxi; y R2 es -H o metilo, para uso en el tratamiento de cáncer de páncreas.

公开(公告)号：NZ718923A

公开(公告)日：2021-11-26

申请号：NZ71892314

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00 ,  C07D413/14

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

公开(公告)号：AU2014336917B2

公开(公告)日：2018-11-29

申请号：AU2014336917

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: C07D413/14 ,  A61K31/416 ,  A61K31/5377 ,  A61P35/00

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

公开(公告)号：EA030089B1

公开(公告)日：2018-06-29

申请号：EA201690763

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00 ,  C07D413/14

Abstract: Настоящееизобретениеотноситсяк применениюсоединения, представленногоструктурнойформулой (I)илиегофармацевтическиприемлемойсолидлялеченияракаподжелудочнойжелезы.

公开(公告)号：SG11201602882VA

公开(公告)日：2016-05-30

申请号：SG11201602882V

申请日：2014-10-03

Applicant: UNIV HEALTH NETWORK

Inventor： HEDLEY DAVID W ,  LOHSE INES ,  MASON JACQUELINE M ,  BRAY MARK R

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00 ,  C07D413/14

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.