公开(公告)号：EP2926115A4

公开(公告)日：2016-07-06

申请号：EP13858774

申请日：2013-12-02

Applicant: UNIV NORTH CAROLINA

Inventor： SUPERFINE RICHARD ,  OBERHARDT BRUCE J ,  SPERO RICHARD CHASEN ,  FALVO MICHAEL RICHARD ,  FISER BRIANA LEE ,  TAYLOR RUSSELL MORTON ,  JUDITH ROBERT MICHAEL

IPC: G01N21/17 ,  G01N33/483

CPC classification number: G01N21/47 ,  G01N21/59 ,  G01N21/82 ,  G01N27/22 ,  G01N27/72 ,  G01N33/49 ,  G01N33/4905 ,  G01N2021/825 ,  G01N2201/02 ,  G01N2201/062

Abstract: Methods, systems, and computer readable media for determining physical properties of a specimen in a portable point of care device are disclosed. According to one aspect, a method includes placing a specimen onto an active surface that includes a plurality of microposts extending outwards from a substrate, wherein each micropost includes a proximal end attached to the substrate and a distal end opposite the proximal end and generating an actuation force in proximity to the micropost array that compels at least some of the microposts to exhibit motion. The method further includes detecting light that is emitted by an illumination source and interacts with the active surface while the at least some microposts exhibit motion in response to the actuation force, measuring data that represents the detected light interacting with the active surface, and determining at least one physical property of the specimen based on the measured data.

公开(公告)号：EP2446259A4

公开(公告)日：2015-04-01

申请号：EP10792732

申请日：2010-06-25

Applicant: UNIV NORTH CAROLINA

Inventor： SUPERFINE RICHARD ,  SPERO RICHARD CHASEN ,  SHIELDS ADAM RICHARD ,  EVANS BENJAMIN AARON ,  FISER BRIANA LEE

IPC: G01N33/48 ,  B01L3/00 ,  G01H11/02 ,  G01N21/25 ,  G01N21/47 ,  G01N27/00 ,  G01N29/02

CPC classification number: G01N11/16 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/0663 ,  B01L2300/0851 ,  B29C39/026 ,  B29K2083/00 ,  B29K2869/00 ,  B29L2031/756 ,  B82Y15/00 ,  C23F1/04 ,  G01N29/022 ,  G01N33/4905 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/02827

Abstract: Methods, systems, and computer readable media for using actuated surface-attached posts for assessing biofluid rheology are disclosed. According to one aspect, a method for testing properties of a biofluid specimen includes placing the specimen onto a micropost array having a plurality of microposts extending outwards from a substrate, wherein each micropost includes a proximal end attached to the substrate and a distal end opposite the proximal end, and generating an actuation force in proximity to the micropost array to actuate the microposts, thereby compelling at least some of the microposts to exhibit motion. The method further includes measuring the motion of at least one of the microposts in response to the actuation force and determining a property of the specimen based on the measured motion of the at least one micropost.