公开(公告)号：EP2446259A4

公开(公告)日：2015-04-01

申请号：EP10792732

申请日：2010-06-25

Applicant: UNIV NORTH CAROLINA

Inventor： SUPERFINE RICHARD ,  SPERO RICHARD CHASEN ,  SHIELDS ADAM RICHARD ,  EVANS BENJAMIN AARON ,  FISER BRIANA LEE

IPC: G01N33/48 ,  B01L3/00 ,  G01H11/02 ,  G01N21/25 ,  G01N21/47 ,  G01N27/00 ,  G01N29/02

CPC classification number: G01N11/16 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/0663 ,  B01L2300/0851 ,  B29C39/026 ,  B29K2083/00 ,  B29K2869/00 ,  B29L2031/756 ,  B82Y15/00 ,  C23F1/04 ,  G01N29/022 ,  G01N33/4905 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/02827

Abstract: Methods, systems, and computer readable media for using actuated surface-attached posts for assessing biofluid rheology are disclosed. According to one aspect, a method for testing properties of a biofluid specimen includes placing the specimen onto a micropost array having a plurality of microposts extending outwards from a substrate, wherein each micropost includes a proximal end attached to the substrate and a distal end opposite the proximal end, and generating an actuation force in proximity to the micropost array to actuate the microposts, thereby compelling at least some of the microposts to exhibit motion. The method further includes measuring the motion of at least one of the microposts in response to the actuation force and determining a property of the specimen based on the measured motion of the at least one micropost.