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    TISSUE EVALUATION USING GLOBAL TISSUE CHARACTERISTICS OF NON-INVASIVE IMAGING AND SYSTEMS FOR DETERMINING GLOBAL TISSUE CHARACTERISTICS OF IMAGES
    5.
    发明专利
    TISSUE EVALUATION USING GLOBAL TISSUE CHARACTERISTICS OF NON-INVASIVE IMAGING AND SYSTEMS FOR DETERMINING GLOBAL TISSUE CHARACTERISTICS OF IMAGES 未知

    公开(公告)号：CA2555373C

    公开(公告)日：2014-04-29

    申请号：CA2555373

    申请日：2005-02-04

    Applicant: UNIV WAKE FOREST HEALTH SCIENCES

    Inventor： HUNDLEY WILLIAM GREGORY ,  HAMILTON CRAIG A ,  LANE KIMBERLY ,  MORGAN TIM ,  TORTI FRANK

    IPC: A61B5/00 ,  A61B5/05 ,  A61B5/055 ,  A61B6/03 ,  G01R33/28 ,  G01R33/56 ,  G06T7/00

    Abstract: Evaluating tissue characteristics including identification of injured tissue or alteration of the ratios of native tissue components such as shifting the amounts of normal myocytes and fibrotic tissue in the heart, identifying increases in the amount of extracellular components or fluid (like edema or extracellular matrix proteins), or detecting infiltration of tumor cells or mediators of inflammation into the tissue of interest in a patient, such as a human being, is provided by obtaining a first image of tissue including a region of interest from a first acquisition, for example, after administration of a contrast agent to the patient, and obtaining a second image of the tissue including the region of interest during a second, subsequent acquisition, for example, after administration of a contrast agent to the patient. The subsequent acquisition may be obtained after a period of time to determine if injury has occurred during that period of time. The region of interest may include heart, blood, muscle, brain, nerve, skeletal, skeletal muscle, liver, kidney, lung, pancreas, endocrine, gastrointestinal and/or genitourinary tissue. A global characteristic of the region of interest of the first image and of the second image is determined to allow a comparison of the global characteristic of the first image and the second image to determine a potential for a change in global tissue characteristics. Such a comparison may include comparison of mean, average characteristics, histogram shape, such as skew and kurtosis, or distribution of intensities within the histogram.

    Non-invasive imaging and for determining global tissue characteristics
    9.
    发明专利
    Non-invasive imaging and for determining global tissue characteristics 未知

    公开(公告)号：AU2005212310B2

    公开(公告)日：2010-11-18

    申请号：AU2005212310

    申请日：2005-02-04

    Applicant: UNIV WAKE FOREST HEALTH SCIENCES

    Inventor： MORGAN TIM ,  TORTI FRANK ,  HAMILTON CRAIG A ,  HUNDLEY WILLIAM GREGORY ,  LANE KIMBERLY

    IPC: A61B5/055 ,  A61B5/05 ,  A61B6/03 ,  G01R33/28 ,  G01R33/56 ,  G06T7/00

    Abstract: Evaluating tissue characteristics including identification of injured tissue is provided by obtaining a first image of tissue including a region of interest from a first acquisition, for example, after administration of a contrast agent, and obtaining a second image of the tissue including the region of interest during a second, subsequent acquisition, for example, after administration of a contrast agent. A global characteristic of the region of interest of the first image and of the second image is determined to allow a comparison of the global characteristic of the first image and the second image to determine a potential for a change in global tissue characteristics. Such a comparison may include comparison of mean, average characteristics, histogram shape, such as skew and kurtosis, or distribution of intensities within the histogram.

    TISSUE EVALUATION USING GLOBAL TISSUE CHARACTERISTICS OF NON-INVASIVE IMAGING AND SYSTEMS FOR DETERMINING GLOBAL TISSUE CHARACTERISTICS OF IMAGES
    10.
    发明专利
    TISSUE EVALUATION USING GLOBAL TISSUE CHARACTERISTICS OF NON-INVASIVE IMAGING AND SYSTEMS FOR DETERMINING GLOBAL TISSUE CHARACTERISTICS OF IMAGES 未知

    公开(公告)号：CA2555373A1

    公开(公告)日：2005-08-25

    申请号：CA2555373

    申请日：2005-02-04

    Applicant: UNIV WAKE FOREST HEALTH SCIENCES

    Inventor： HUNDLEY WILLIAM GREGORY ,  HAMILTON CRAIG A ,  TORTI FRANK ,  LANE KIMBERLY ,  MORGAN TIM

    IPC: A61B5/00 ,  A61B5/05 ,  A61B5/055 ,  A61B6/03 ,  G01R33/28 ,  G01R33/56 ,  G06T7/00

    Abstract: Evaluating tissue characteristics including identification of injured tissue or alteration of the ratios of native tissue components such as shifting the amounts of normal myocytes and fibrotic tissue in the heart, identifying increases in the amount of extracellular components or fluid (like edema or extracellular matrix proteins), or detecting infiltration of tumor cells or mediators of inflammation into the tissue of interest in a patient, such as a human being, is provided by obtaining a first image of tissue including a region of interest from a first acquisition, for example, after administrati on of a contrast agent to the patient, and obtaining a second image of the tiss ue including the region of interest during a second, subsequent acquisition, fo r example, after administration of a contrast agent to the patient. The subsequent acquisition may be obtained after a period of time to determine i f injury has occurred during that period of time. The region of interest may include heart, blood, muscle, brain, nerve, skeletal, skeletal muscle, liver , kidney, lung, pancreas, endocrine, gastrointestinal and/or genitourinary tissue. A global characteristic of the region of interest of the first image and of the second image is determined to allow a comparison of the global characteristic ofthe first image and the second image to determine a potential for a change in global tissue characteristics. Such a comparison m ay include comparison of mean, average characteristics, histogram shape, such a s skew and kurtosis, or distribution of intensities within the histogram.

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