中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

31 records (took 0.029 seconds)

    MOLECULAR CLONES PRODUCING RECOMBINANT DNA ANTIGENS OF THE HARDS VIRUS
    1.
    发明申请
    MOLECULAR CLONES PRODUCING RECOMBINANT DNA ANTIGENS OF THE HARDS VIRUS 审中-公开
    分子克隆生产重组DNA抗原的硬体病毒

    公开(公告)号：WO1995006250A1

    公开(公告)日：1995-03-02

    申请号：PCT/US1994009416

    申请日：1994-08-25

    Applicant: UNIVERSITY OF NEW MEXICO

    Inventor： UNIVERSITY OF NEW MEXICO ,  HJELLE, Brian ,  JENISON, Steve

    IPC: G01N33/53

    CPC classification number: C07K14/005 ,  A61K39/00 ,  C07K2319/00 ,  C12N2760/12122

    Abstract: The invention provides HARDS virus rDNA for expression in molecular clones. The expressed products are useful in immunodiagnostics, prophylactics, and therapeutics for the HARDS virus and related hantaviruses. Of particular interest are a type-specific epitope of the HARDS virus G1 protein, and dominant epitopes of the HARDS virus N protein cross-reactive with antibodies to the HARDS virus and the related hantavirus PHV, both expressed by cDNA clones according to the invention.

    Abstract translation: 本发明提供用于在分子克隆中表达的HARDS病毒rDNA。 表达的产品可用于HARDS病毒和相关的汉坦病毒的免疫诊断，预防和治疗。 特别感兴趣的是HARDS病毒G1蛋白的特异性表位，以及与针对本发明的cDNA克隆表达的HARDS病毒和相关汉坦病毒PHV的抗体交叉反应的HARDS病毒N蛋白质的优势表位。

    REGENERATIVE OPTICAL PULSE GENERATOR
    6.
    发明申请
    REGENERATIVE OPTICAL PULSE GENERATOR 审中-公开
    再生光学脉冲发生器

    公开(公告)号：WO1994015387A1

    公开(公告)日：1994-07-07

    申请号：PCT/US1993012731

    申请日：1993-12-22

    Applicant: UNIVERSITY OF NEW MEXICO

    Inventor： UNIVERSITY OF NEW MEXICO ,  YAN, Chi ,  REDDY, Kalidev'Apura, P., J. ,  JAIN, Ravinder, K. ,  McINERNEY, John, G.

    IPC: H01S03/098

    CPC classification number: H01S5/06216 ,  H01S5/06223 ,  H01S5/0658

    Abstract: Filtered regenerative feedback is used to modulate a laser or other source of electromagnetic radiation to generate optical pulses whose amplitudes and repetition rates are continuously tunable. The technique involves converting, by means of a photodetector (9), a portion of the radiation produced by a modulatable electromagnetic radiation source (1, 7) into a control signal, filtering the control signal through a bandpass filter (3, 10), and modulating the modulatable radiation source with the filtered control signal to produce pulses. This technique is in principle applicable to any source of electromagnetic radiation and is especially effective for semiconductor diode lasers.

    Abstract translation: 过滤的再生反馈用于调制激光或其他电磁辐射源，以产生振幅和重复率连续可调的光脉冲。 该技术涉及通过光电检测器（9）将由可调制电磁辐射源（1,7）产生的辐射的一部分转换成控制信号，通过带通滤波器（3,10）对控制信号进行滤波， 并用滤波的控制信号调制可调制的辐射源，以产生脉冲。 该技术原则上适用于任何电磁辐射源，对半导体二极管激光器尤为有效。

    BIOMODULATORS AS UNIVERSAL IMAGING AGENTS
    7.
    发明申请
    BIOMODULATORS AS UNIVERSAL IMAGING AGENTS 审中-公开
    生物体作为通用成像剂

    公开(公告)号：WO1992019264A1

    公开(公告)日：1992-11-12

    申请号：PCT/US1992003675

    申请日：1992-05-01

    Applicant: UNIVERSITY OF NEW MEXICO

    Inventor： UNIVERSITY OF NEW MEXICO ,  BORN, Jerry, L. ,  ESHIMA, Dennis ,  MANN, Paul, L. ,  MATWIYOFF, Nicholas, A. ,  KROH, Frank, O.

    IPC: A61K39/02

    CPC classification number: A61K49/085 ,  A61K47/6415 ,  A61K49/10 ,  A61K49/14 ,  A61K51/0497 ,  A61K51/08 ,  A61K51/081 ,  A61K2121/00 ,  A61K2123/00

    Abstract: Biomodulators, optionally linked to imaging-active moieties, can be administered to a host to enhance images thereof, e.g., NMR-, X-ray- or radio-images, preferably by increasing aberrant tissue signal intensity. Biomodulators can also condition tissue to enhance uptake of otherwise non-specific imaging agents. When linked to drugs, biomodulators can target the same to particular sites in the body. Biomodulators can be also administered together with an agent such as a drug or an imaging agent (specific or non-specific) structurally modified to take advantage of perturbations of cell oligosaccharide displays caused by biomodulators, to enhance images of a host, e.g., NMR-, X-ray- or radio-images, preferably by increasing aberrant tissue signal intensity. Biomodulators condition tissue to enhance or otherwise modify up-take of the drug or structurally modified agent.

    Abstract translation: 优选通过增加异常组织信号强度，任选地与成像活性部分连接的生物调节剂可以施用于宿主以增强其图像，例如NMR-，X射线或放射图像。 生物调节剂还可以调节组织以增强非特异性成像剂的吸收。 当与药物相关时，生物调节剂可以将其靶向到身体中的特定部位。 生物调节剂还可与诸如药物或成像剂（特异性或非特异性）的试剂一起施用，其结构修饰以利用由生物调节剂引起的细胞寡糖显示的扰动，以增强宿主的图像，例如NMR- ，X射线或放射线图像，优选通过增加异常组织信号强度。 生物调节剂调节组织以增强或以其它方式改变药物或结构改性剂的摄取。

    TREATMENT OF ABERRANT CELLULAR STATES WITH BIOMODULATORS
    8.
    发明申请
    TREATMENT OF ABERRANT CELLULAR STATES WITH BIOMODULATORS 审中-公开
    用生物调节剂处理细胞细胞

    公开(公告)号：WO1992019240A1

    公开(公告)日：1992-11-12

    申请号：PCT/US1992003672

    申请日：1992-05-01

    Applicant: UNIVERSITY OF NEW MEXICO

    Inventor： UNIVERSITY OF NEW MEXICO ,  MANN, Paul, L. ,  MASH, Eugene ,  SCALLEN, Terence, J.

    IPC: A61K31/44

    CPC classification number: A61K31/445 ,  A61K31/19 ,  A61K31/4045 ,  A61K31/415 ,  A61K31/4164 ,  A61K2039/55511 ,  A61K2039/55594 ,  C12N2501/999 ,  Y10S514/883

    Abstract: Biomodulators, which regulate cellular differentiation and proliferation, as well as methods of use thereof, e.g., for treating various conditions, e.g., cancer, senescence, immunological disorders and vascular disease; for stimulating normal tissue architecture after injury; for vaccination; for stimulating the production of biologically important molecules by cells or organs in culture; for maintaining organs or tissues outside of a body after removal from the body and prior to transplantation; and for producing vascular grafts for transplantation; are provided.

    Abstract translation: 调节细胞分化和增殖的生物调节剂，以及其使用方法，例如用于治疗各种病症，例如癌症，衰老，免疫学疾病和血管疾病; 用于刺激损伤后的正常组织结构; 接种疫苗 用于刺激培养物中细胞或器官生物重要分子的生成; 用于在身体移除后和移植前将器官或组织保持在身体外部; 并用于生产用于移植的血管移植物; 被提供。

    EVERTING FORCEPS
    9.
    发明申请
    EVERTING FORCEPS 审中-公开
    勇敢的力量

    公开(公告)号：WO1991013590A1

    公开(公告)日：1991-09-19

    申请号：PCT/US1990001044

    申请日：1990-03-06

    Applicant: UNIVERSITY OF NEW MEXICO ,  CUSHMAN, Robert, M.

    Inventor： UNIVERSITY OF NEW MEXICO ,  KIRSCH, Wolff, Mayer ,  ZHU, Yong, Hua

    IPC: A61B17/28

    CPC classification number: A61B17/30 ,  A61B17/11

    Abstract: A forceps for holding and everting vessels in an anastomosis procedure includes three cooperating jaws (32, 34, 36) mounted at the ends of respective relatively movable legs (10, 12, 14). The legs (10, 12, 14) can be independently manipulated in order to secure and evert first one vessel, then another in apposition to the first, so that clips or sutures can be applied to complete the anastomosis.

    LONG-LIFE MEMBRANE ELECTRODE FOR NON-IONIC SPECIES
    10.
    发明申请
    LONG-LIFE MEMBRANE ELECTRODE FOR NON-IONIC SPECIES 审中-公开
    长寿命非电离子膜电极

    公开(公告)号：WO1989005605A1

    公开(公告)日：1989-06-29

    申请号：PCT/US1988004533

    申请日：1988-12-19

    Applicant: UNIVERSITY OF NEW MEXICO

    Inventor： UNIVERSITY OF NEW MEXICO ,  WILKINS, Ebtisam, S.

    IPC: A61B05/00

    CPC classification number: G01N27/3335

    Abstract: An improved membrane electrode (11) for measuring the concentration of a non-ionic species in an essentially aqueous medium comprising: an electrically conductive substrate (17); a first coating (13) surrounding said substrate (17) composed of a mixture of polymeric material, an anion exchange material, and a water-insoluble alkaline earth metal salt of said non-ionic species, and a hydrogel coating (15) of material surrounding said first coating (13) having a positive charge of sufficient potential to prevent leaching of the substantial amounts of the alkaline earth metal component of said salt.

Patent Agency Ranking