公开(公告)号：US20230257420A1

公开(公告)日：2023-08-17

申请号：US18011649

申请日：2021-06-22

Applicant: University of Houston System

Inventor： Bin Guo ,  Damith Gomika Udugamasooriya ,  Xinli Liu ,  Satya Prakash Shukla ,  Kwang Bog Cho ,  Xue Zhou

IPC: C07K7/06 ,  A61K47/64 ,  A61P25/00

CPC classification number: C07K7/06 ,  A61K47/645 ,  A61P25/00

Abstract: Compounds disclosed herein have been shown to bind to the transferrin receptor making them capable of crossing the blood-brain barrier (BBB) and useful for treating diseases or disorders of the brain, such as cancer, ischemic stroke, Alzheimer's disease, or Parkinson's disease.