COOLING OF PUMP HEADS IN CARBON DIOXIDE CHROMATOGRAPHY SYSTEMS
    1.
    发明申请
    COOLING OF PUMP HEADS IN CARBON DIOXIDE CHROMATOGRAPHY SYSTEMS 审中-公开
    泵头在二氧化碳色谱系统中的冷却

    公开(公告)号:WO2016164544A8

    公开(公告)日:2016-11-17

    申请号:PCT/US2016026386

    申请日:2016-04-07

    CPC classification number: F25B25/005 B01D15/40 G01N30/30

    Abstract: The present disclosure relates to methodologies, systems and apparatus for cooling pump heads and providing balanced cooling and heat transfer between multiple pump heads. Multi-pump systems that are used to pump fluids that vary greatly in density with minor changes in temperature, such as the mobile phase of a C02-based chromatography system, require highly stable temperature conditions. In order to achieve a substantially equal average heat transfer between multiple pump heads and a coolant fluid, coolant fluid may be flowed through coolant passageways within the pump heads in a recursive and/or parallel coolant flow patterns. Such recursive and/or parallel coolant fluid flow patterns provide increased stability in temperature, compressibility, and density of the fluids passing through a multi-pump system.

    Abstract translation: 本公开涉及用于冷却泵头并在多个泵头之间提供平衡的冷却和热传递的方法,系统和设备。 用于泵送密度变化很大且温度变化较小的流体的多泵系统(例如基于CO 2的色谱系统的流动相)需要高度稳定的温度条件。 为了在多个泵头与冷却剂流体之间实现基本相等的平均热传递,冷却剂流体可以以递归和/或平行冷却剂流动模式流过泵头内的冷却剂通路。 这种递归和/或平行的冷却剂流体流动模式提供了增加的温度稳定性,可压缩性和通过多泵系统的流体密度。

    SELECT VALVE FOR LIQUID CHROMATOGRAPHY SYSTEMS
    2.
    发明公开
    SELECT VALVE FOR LIQUID CHROMATOGRAPHY SYSTEMS 审中-公开
    液相色谱系统的换档阀

    公开(公告)号:EP2788639A4

    公开(公告)日:2015-09-02

    申请号:EP12856225

    申请日:2012-12-07

    Abstract: A liquid chromatography system includes a pumping system with a selector valve in fluidic communication with a pump inlet. The selector valve switches between a first position, in which the selector valve fluidically couples a solvent reservoir to the pump inlet, and a second position, in which the selector valve fluidically couples a pressurized source of liquefied carbon dioxide (for example) to the pump inlet. The liquid chromatography system can perform as a HPLC system (or as an UPLC system) when the selector valve is in the first position and as a CO2-based chromatography system when the selector valve is in the second position. The selector valve can have a third position in which both the fluidic pathway between the solvent reservoir and the pump inlet and the fluidic pathway between the pressurized source and the pump inlet are blocked. This shut-off position advantageously facilitates system maintenance.

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