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    CARBON DIOXIDE LIQUID PHASE
    1.
    发明申请
    CARBON DIOXIDE LIQUID PHASE 审中-公开
    二氧化碳液相

    公开(公告)号：WO2014204843A1

    公开(公告)日：2014-12-24

    申请号：PCT/US2014/042504

    申请日：2014-06-16

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： DUMAS, Robert J. ,  JOUDREY, Kurt ,  JACKSON, Michael R.

    IPC: F04B53/08 ,  F04B15/08 ,  F16K15/18

    CPC classification number: G01N30/16 ,  F04B13/00 ,  F04B15/06 ,  F04B15/08 ,  F04B19/22 ,  F04B23/06 ,  F04B49/065 ,  F04B53/06 ,  F04B53/08 ,  F04B53/10 ,  F04B53/14 ,  F04B53/16 ,  F04B2015/0818 ,  G01N30/68 ,  G01N30/7206 ,  G01N30/74 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2030/326

    Abstract: Systems and methods for pumping carbon dioxide in a chromatography system include an actuator that receives and compresses carbon dioxide at or above room temperature at a given pressure to put the carbon dioxide in or near supercritical form. This actuator can be a pre-pump disposed on the intake side of a pumping system. Alternatively, this actuator can be a primary actuator in the pumping system. The actuator includes an intake chamber that receives the carbon dioxide and a movable plunger extending into and closely received by the intake chamber. The plunger has a diameter and stroke length adapted to compress the carbon dioxide received by the intake chamber in sufficient volume at the given pressure to put the carbon dioxide in or near supercritical form at or above room temperature. A metered amount of the carbon dioxide in or near supercritical form can then be pumped.

    Abstract translation: 用于在色谱系统中抽取二氧化碳的系统和方法包括致动器，其在给定压力下接收和压缩室温或室温以上的二氧化碳，以将二氧化碳置于或接近超临界形式。 该致动器可以是设置在泵送系统的进气侧的预泵。 或者，该致动器可以是泵送系统中的主要致动器。 致动器包括进气室，其容纳二氧化碳和可移动的柱塞，该柱塞延伸到进气室中并且紧密地被进气室接收。 柱塞具有直径和冲程长度，其适于在给定压力下以足够的体积压缩由进气室接收的二氧化碳，以将二氧化碳置于室温或室温以上或接近超临界状态。 然后可以泵送超临界形式的或接近超临界形式的计量量的二氧化碳。

    FLUID MIXER
    3.
    发明申请
    FLUID MIXER 审中-公开

    公开(公告)号：WO2019050698A1

    公开(公告)日：2019-03-14

    申请号：PCT/US2018/047899

    申请日：2018-08-24

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： JACKSON, Michael R. ,  MACKINNON, Peter

    IPC: B01F5/06 ,  B01F13/00

    Abstract: A fluid mixer 300 includes a flow splitter 320, a plurality of channels 370, 360, 340 and a mixing chamber 330. The flow splitter includes an inlet 321 for receiving a flow of fluid and is configured to split the flow of fluid into a plurality of fluid streams 322. Each channel conveys a corresponding one of the fluid streams. The channels have dissimilar volumes and a substantially identical pressure drop across the length of each channel. The mixing chamber includes a plurality of inlets. Each of the inlets of the mixing chamber is connected to a corresponding one of the channels.

    EQUAL DISPERSION SPLIT-FLOW MIXER
    4.
    发明申请
    EQUAL DISPERSION SPLIT-FLOW MIXER 审中-公开

    公开(公告)号：WO2022245566A1

    公开(公告)日：2022-11-24

    申请号：PCT/US2022/028299

    申请日：2022-05-09

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： MACKINNON, Peter ,  JACKSON, Michael R.

    IPC: G01N30/34

    Abstract: Disclosed is a liquid chromatography system and mixer (100) for use therein that includes a first split 106 connected to an inlet (102), the first split branching the flow of fluid from the inlet into a first path (108) and a second path (110); a second split (112) connected to an outlet of the first path, the second split branching the first path into a third path (114) and a fourth path (116); and a third split (118) connected to an outlet of the second path, the third split branching the second path into a fifth path (120) and a sixth path (122). The first path and the second path are offset by a first predetermined volume, the third path and the fourth path are offset by a second predetermined volume, and the fifth path and the sixth path are also offset by the second predetermined volume.

    THERMALLY-CONTROLLED LOW PRESSURE MIXING SYSTEM FOR LIQUID CHROMATOGRAPHY
    5.
    发明申请
    THERMALLY-CONTROLLED LOW PRESSURE MIXING SYSTEM FOR LIQUID CHROMATOGRAPHY 审中-公开

    公开(公告)号：WO2022169710A1

    公开(公告)日：2022-08-11

    申请号：PCT/US2022/014555

    申请日：2022-01-31

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： RAYMOND, Timothy M. ,  MACKINNON, Peter ,  JACKSON, Michael R.

    IPC: G01N30/30 ,  G01N30/34 ,  G01N30/88

    Abstract: Described is a solvent manager for a liquid chromatography system. The solvent manager includes a temperature control module, a plurality of solvent reservoirs, a gradient proportioning valve and a degasser. The temperature control module maintains a substantially constant temperature of one or more of the plurality of solvent reservoirs, gradient proportioning valve and degasser. The temperature control module may include a thermal chamber having an enclosure with a thermally controlled internal environment and may also include an active thermal element such as one or more heaters. The enclosure may surround at least one of the plurality of solvent reservoirs, gradient proportioning valve and degasser. The temperature control module reduces the negative effects on solvent composition that result from temperature-dependent changes in solvent viscosities and solvent densities. Such changes affect the retention times of analytes eluted from the chromatographic column.

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